P38085 · TAT1_YEAST
- ProteinValine/tyrosine/tryptophan amino-acid permease 1
- GeneTAT1
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids619 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score5/5
Function
function
High-affinity transport of valine and tyrosine. Low-affinity transport of tryptophan. Can also transport L-cysteine.
Miscellaneous
Present with 504 molecules/cell in log phase SD medium.
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | cell periphery | |
Cellular Component | endoplasmic reticulum | |
Cellular Component | membrane | |
Cellular Component | plasma membrane | |
Molecular Function | amino acid transmembrane transporter activity | |
Molecular Function | low-affinity tryptophan transmembrane transporter activity | |
Biological Process | amino acid transmembrane transport | |
Biological Process | amino acid transport | |
Biological Process | transmembrane transport | |
Biological Process | tryptophan transport | |
Biological Process | tyrosine transport |
Keywords
- Biological process
Enzyme and pathway databases
Protein family/group databases
Names & Taxonomy
Protein names
- Recommended nameValine/tyrosine/tryptophan amino-acid permease 1
- Alternative names
Gene names
Organism names
- Strains
- Taxonomic lineageEukaryota > Fungi > Dikarya > Ascomycota > Saccharomycotina > Saccharomycetes > Saccharomycetales > Saccharomycetaceae > Saccharomyces
Accessions
- Primary accessionP38085
- Secondary accessions
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Membrane ; Multi-pass membrane protein
Features
Showing features for topological domain, transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Topological domain | 1-99 | Cytoplasmic | |||
Transmembrane | 100-120 | Helical | |||
Topological domain | 121-122 | Extracellular | |||
Transmembrane | 123-143 | Helical | |||
Topological domain | 144-172 | Cytoplasmic | |||
Transmembrane | 173-193 | Helical | |||
Topological domain | 194-204 | Extracellular | |||
Transmembrane | 205-225 | Helical | |||
Topological domain | 226-233 | Cytoplasmic | |||
Transmembrane | 234-254 | Helical | |||
Topological domain | 255-281 | Extracellular | |||
Transmembrane | 282-302 | Helical | |||
Topological domain | 303-320 | Cytoplasmic | |||
Transmembrane | 321-341 | Helical | |||
Topological domain | 342-368 | Extracellular | |||
Transmembrane | 369-389 | Helical | |||
Topological domain | 390-422 | Cytoplasmic | |||
Transmembrane | 423-443 | Helical | |||
Topological domain | 444-446 | Extracellular | |||
Transmembrane | 447-467 | Helical | |||
Topological domain | 468-499 | Cytoplasmic | |||
Transmembrane | 500-520 | Helical | |||
Topological domain | 521-529 | Extracellular | |||
Transmembrane | 530-550 | Helical | |||
Topological domain | 551-619 | Cytoplasmic | |||
Keywords
- Cellular component
PTM/Processing
Features
Showing features for chain, modified residue, cross-link.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000054162 | 1-619 | Valine/tyrosine/tryptophan amino-acid permease 1 | ||
Modified residue | 13 | Phosphoserine | |||
Cross-link | 39 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) | |||
Modified residue | 80 | Phosphoserine | |||
Modified residue | 84 | Phosphoserine | |||
Keywords
- PTM
Proteomic databases
PTM databases
Structure
Family & Domains
Features
Showing features for region, compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Region | 1-57 | Disordered | |||
Compositional bias | 21-57 | Basic and acidic residues | |||
Sequence similarities
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length619
- Mass (Da)68,758
- Last updated1994-10-01 v1
- Checksum7A575A9BF2A084F8
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 21-57 | Basic and acidic residues | |||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
U10503 EMBL· GenBank· DDBJ | AAA50552.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
X79151 EMBL· GenBank· DDBJ | CAA55778.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
X76294 EMBL· GenBank· DDBJ | CAA53926.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
Z35938 EMBL· GenBank· DDBJ | CAA85013.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
BK006936 EMBL· GenBank· DDBJ | DAA07188.1 EMBL· GenBank· DDBJ | Genomic DNA |