P37061 · NAOX_ENTFA
- ProteinNADH oxidase
- Genenox
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids446 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score4/5
Function
function
Catalyzes the four-electron reduction of molecular oxygen to water.
Catalytic activity
NADH oxidase
2 NADH + O2 + 2 H+ = 2 NAD+ + 2 H2O
Cofactor
Note: Binds 1 FAD per subunit.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 7-11 | FAD (UniProtKB | ChEBI) | |||
Active site | 10 | Proton acceptor | |||
Binding site | 32 | FAD (UniProtKB | ChEBI) | |||
Active site | 42 | Redox-active | |||
Binding site | 42 | FAD (UniProtKB | ChEBI) | |||
Binding site | 79 | FAD (UniProtKB | ChEBI) | |||
Binding site | 110-113 | FAD (UniProtKB | ChEBI) | |||
Binding site | 132 | FAD (UniProtKB | ChEBI) | |||
Binding site | 150-165 | NAD+ (UniProtKB | ChEBI) | |||
Binding site | 157 | FAD (UniProtKB | ChEBI) | |||
Binding site | 177 | NAD+ (UniProtKB | ChEBI) | |||
Binding site | 186 | NAD+ (UniProtKB | ChEBI) | |||
Binding site | 243 | NAD+ (UniProtKB | ChEBI) | |||
Binding site | 271-281 | FAD (UniProtKB | ChEBI) | |||
Binding site | 298 | FAD (UniProtKB | ChEBI) | |||
Binding site | 299 | FAD (UniProtKB | ChEBI) | |||
Binding site | 300 | FAD (UniProtKB | ChEBI) | |||
Binding site | 328 | NAD+ (UniProtKB | ChEBI) | |||
Binding site | 424 | FAD (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | NADH dehydrogenase (ubiquinone) activity |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Protein family/group databases
Names & Taxonomy
Protein names
- Recommended nameNADH oxidase
- EC number
- Short namesNOXase
Gene names
Organism names
- Strains
- Taxonomic lineageBacteria > Bacillota > Bacilli > Lactobacillales > Enterococcaceae > Enterococcus
Accessions
- Primary accessionP37061
Proteomes
PTM/Processing
Features
Showing features for chain, modified residue.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000184701 | 1-446 | NADH oxidase | ||
Modified residue | 42 | Cysteine sulfinic acid (-SO2H) | |||
Post-translational modification
The N-terminus is blocked.
Keywords
- PTM
Interaction
Structure
Sequence
- Sequence statusComplete
- Length446
- Mass (Da)48,915
- Last updated1994-06-01 v1
- ChecksumD0762A47FC3DC071
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
X68847 EMBL· GenBank· DDBJ | CAA48728.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AE016830 EMBL· GenBank· DDBJ | AAO81372.1 EMBL· GenBank· DDBJ | Genomic DNA |