P36267 · GGT_PSEUA

Function

Catalytic activity

Pathway

Sulfur metabolism; glutathione metabolism.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site100L-glutamate (UniProtKB | ChEBI)
Active site376Nucleophile
Binding site394L-glutamate (UniProtKB | ChEBI)
Binding site396L-glutamate (UniProtKB | ChEBI)
Binding site415L-glutamate (UniProtKB | ChEBI)
Binding site418L-glutamate (UniProtKB | ChEBI)
Binding site447-448L-glutamate (UniProtKB | ChEBI)
Binding site468-469L-glutamate (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentperiplasmic space
Molecular Functionglutathione hydrolase activity
Molecular Functionleukotriene C4 gamma-glutamyl transferase activity
Biological Processglutathione biosynthetic process
Biological Processglutathione catabolic process
Biological Processproteolysis

Keywords

Enzyme and pathway databases

Protein family/group databases

Names & Taxonomy

Protein names

Gene names

    • Name
      ggt

Organism names

Accessions

  • Primary accession
    P36267

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for signal, chain.

TypeIDPosition(s)Description
Signal1-24
ChainPRO_000001105425-375Glutathione hydrolase large chain
ChainPRO_0000011055376-575Glutathione hydrolase small chain

Post-translational modification

Cleaved by autocatalysis into a large and a small subunit.

Keywords

Interaction

Subunit

This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

Structure

Family & Domains

Sequence similarities

Belongs to the gamma-glutamyltransferase family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    575
  • Mass (Da)
    61,301
  • Last updated
    1994-06-01 v1
  • Checksum
    CF2EB69F02CD0201
MKNQTFSKALLATALSCALFNVHAASQAPVGAENGMVVTAQHIASKVGVEVLKSGGNAIDAAVAVGYALAVVYPAAGNIGGGGFMTIQLADGRKTFLDFREKAPLAATANMYLDKDGNVIKGASTTGYLAVGVPGTVSGMEYAREKYGTKTRQQLISPAITLADKGFVLEQGDVDMLWTSTKDFEKDRANSGAIFMNKGQPFQPGERLVQKDLARTLRLISAKGTDGFYKGEVADKLVASMKAGGGIITQADLDQYKTRELAPVECDYRGYHVVSAPPPSSGGVVICEIMNILEGYPMKELGYHSAQGVHYTIEAMRHAYVDRNSYLGDPDFVKNPLAHLLDKDYAAKIRAAINPQKAGISQEIKPGVPPHEGSNTTHYSIVDKDGNAVSVTYTLNDWFGAKVMANGTGVLLNDEMDDFTSKVGVPNMYGLIQGEANAIGPGRRPLSSMSPTIVTKDGKTVMVVGTPGGSRIITATLLTMLNMIDYGMNLQEAVDAPRFHQQWMPESTNIEAFALSPDTQKILESWGQKFAGPQPANHIAAILVGAPSLGGKPIGKNRFYGANDPRRNTGLALGY

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
S63255
EMBL· GenBank· DDBJ
AAC60442.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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