P36005 · KDX1_YEAST

Function

function

Serine/threonine-protein kinase involved in the SLT2 mitogen-activated (MAP) kinase signaling pathway that regulates cell wall integrity. May also be involved in the mating pheromone and the CWI MAPK pathways.

Catalytic activity

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site29-37ATP (UniProtKB | ChEBI)
Binding site55ATP (UniProtKB | ChEBI)
Active site153Proton acceptor

GO annotations

AspectTerm
Cellular Componentcyclin-dependent protein kinase holoenzyme complex
Cellular Componentcytoplasm
Cellular Componentnucleus
Molecular FunctionATP binding
Molecular Functioncyclin binding
Molecular Functioncyclin-dependent protein serine/threonine kinase activity
Molecular Functionprotein serine kinase activity
Molecular Functionprotein serine/threonine kinase activity
Biological ProcessG1/S transition of mitotic cell cycle
Biological Processregulation of G2/M transition of mitotic cell cycle
Biological Processregulation of gene expression
Biological Processsignal transduction

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Serine/threonine-protein kinase KDX1
  • EC number
  • Alternative names
    • Kinase dead X-talker protein 1
    • MPK1-like protein kinase 1

Gene names

    • Name
      KDX1
    • Synonyms
      MLP1
    • ORF names
      YKL615
    • Ordered locus names
      YKL161C

Organism names

Accessions

  • Primary accession
    P36005
  • Secondary accessions
    • D6VX38

Proteomes

Organism-specific databases

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00000861501-433Serine/threonine-protein kinase KDX1

Proteomic databases

PTM databases

Expression

Induction

Accumulates in large amounts when cell wall integrity is compromised.

Interaction

Subunit

Interacts with RLM1.

Protein-protein interaction databases

Miscellaneous

Structure

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain23-318Protein kinase

Sequence similarities

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    433
  • Mass (Da)
    49,633
  • Last updated
    1994-06-01 v1
  • Checksum
    BC27B76B7DB95822
MATDTERCIFRAFGQDFILNKHFHLTGKIGRGSHSLICSSTYTESNEETHVAIRKIPNAFGNKLSCKRTLRELKLLRHLRGHPNIVWLFDTDIVFYPNGALNGVYLYEELMECDLSQIIRSEQRLEDAHFQSFIYQILCALKYIHSANVLHCDLKPKNLLVNSDCQLKICNFGLSCSYSENHKVNDGFIKGYITSIWYKAPEILLNYQECTKAVDIWSTGCILAELLGRKPMFEGKDYVDHLNHILQILGTPPEETLQEIASQKVYNYIFQFGNIPGRSFESILPGANPEALELLKKMLEFDPKKRITVEDALEHPYLSMWHDIDEEFSCQKTFRFEFEHIESMAELGNEVIKEVFDFRKVVRKHPISGDSPSSSLSLEDAIPQEVVQVHPSRKVLPSYSPEFSYVSQLPSLTTTQPYQNLMGISSNSFQGVN

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
Z26877
EMBL· GenBank· DDBJ
CAA81493.1
EMBL· GenBank· DDBJ
Genomic DNA
Z28161
EMBL· GenBank· DDBJ
CAA82003.1
EMBL· GenBank· DDBJ
Genomic DNA
BK006944
EMBL· GenBank· DDBJ
DAA09004.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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