P35631 · AP1_ARATH

Function

function

Transcription factor that promotes early floral meristem identity in synergy with LEAFY. Is required subsequently for the transition of an inflorescence meristem into a floral meristem. Is indispensable for normal development of sepals and petals in flowers. Positively regulates the B class homeotic proteins APETALA3 and PISTILLATA with the cooperation of LEAFY and UFO. Interacts with SEPALLATA3 or AP3/PI heterodimer to form complexes that could be involved in genes regulation during floral meristem development. Positively regulates AGAMOUS in cooperation with LEAFY. Displays a redundant function with CAULIFLOWER in the up-regulation of LEAFY. Together with AGL24 and SVP, controls the identity of the floral meristem and regulates expression of class B, C and E genes. Represses flowering time genes AGL24, SVP and SOC1 in emerging floral meristems.

GO annotations

all annotationsall molecular functionnucleotide bindingmolecular_functionnucleic acid bindingdna bindingchromatin bindingdna-binding transcription factor activityrna bindingcytoskeletal motor activitycatalytic activitynuclease activitysignaling receptor bindingstructural molecule activitytransporter activitybindingprotein bindingtranslation factor activity, rna bindinglipid bindingkinase activitytransferase activityhydrolase activityoxygen bindingenzyme regulator activitycarbohydrate bindingsignaling receptor activitytranslation regulator activitytranscription regulator activityother molecular functionall biological processcarbohydrate metabolic processgeneration of precursor metabolites and energynucleobase-containing compound metabolic processdna metabolic processtranslationlipid metabolic processtransportresponse to stresscell cyclecell communicationsignal transductioncell-cell signalingmulticellular organism developmentcircadian rhythmbiological_processmetabolic processcatabolic processbiosynthetic processresponse to light stimulusresponse to external stimulustropismresponse to biotic stimulusresponse to abiotic stimulusresponse to endogenous stimulusembryo developmentpost-embryonic developmentfruit ripeningabscissionpollinationflower developmentcellular processprogrammed cell deathphotosynthesiscellular component organizationcell growthprotein metabolic processcellular homeostasissecondary metabolic processreproductive processcell differentiationprotein modification processgrowthepigenetic regulation of gene expressionresponse to chemicalanatomical structure developmentregulation of molecular functionother biological processall cellular componentcellular_componentextracellular regioncell wallintracellular anatomical structurenucleusnuclear envelopenucleoplasmnucleoluscytoplasmmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuscytosolribosomecytoskeletonplasma membranechloroplastplastidthylakoidmembraneexternal encapsulating structureother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentnucleus
Molecular FunctionDNA binding
Molecular FunctionDNA-binding transcription factor activity
Molecular Functionprotein heterodimerization activity
Molecular FunctionRNA polymerase II transcription regulatory region sequence-specific DNA binding
Molecular Functiontranscription cis-regulatory region binding
Biological Processcell differentiation
Biological Processfloral meristem determinacy
Biological Processflower development
Biological Processmeristem structural organization
Biological Processpositive regulation of DNA-templated transcription
Biological Processpositive regulation of transcription by RNA polymerase II

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Floral homeotic protein APETALA 1
  • Alternative names
    • Agamous-like MADS-box protein AGL7

Gene names

    • Name
      AP1
    • Synonyms
      AGL7
    • ORF names
      F4N2.9
    • Ordered locus names
      At1g69120

Organism names

  • Taxonomic identifier
  • Strains
    • cv. Landsberg erecta
    • cv. Columbia
    • cv. Bla-1
    • cv. Bretagny
    • cv. Bs-1
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis

Accessions

  • Primary accession
    P35631
  • Secondary accessions
    • Q680D4
    • Q8LA98
    • Q9LQA8

Proteomes

Organism-specific databases

Genome annotation databases

Subcellular Location

Keywords

Phenotypes & Variants

Disruption phenotype

Partial conversion of flowers into shoots and a disruption of sepal and petal development.

Features

Showing features for natural variant.

TypeIDPosition(s)Description
Natural variant85in strain: cv. Chi-1
Natural variant93in strain: cv. Bla-1
Natural variant99in strain: cv. Chi-1
Natural variant100in strain: cv. Landsberg erecta
Natural variant120in strain: cv. Jl-1
Natural variant125in strain: cv. Bla-1
Natural variant166in strain: cv. Jl-1
Natural variant212in strain: cv. Chi-1
Natural variant233in strain: cv. Co-1

Variants

We now provide the "Disease & Variants" viewer in its own tab.

The viewer provides 20 variants from UniProt as well as other sources including ClinVar and dbSNP.

Go to variant viewer

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00001994511-256Floral homeotic protein APETALA 1

Proteomic databases

Expression

Tissue specificity

Expressed in young flower primordia, later becomes localized to sepals and petals.

Induction

Negatively regulated by TFL1 and by the C class floral homeotic protein AGAMOUS. Positively regulated by CAULIFLOWER.

Developmental stage

Expressed at an early stage of floral initiation.

Gene expression databases

Interaction

Subunit

Homodimer capable of binding to CArG-box sequences. Heterodimer with SEP3, AP1 and SVP. Binds AP3/PI to form a ternary complex. Interacts with the SEU-LUG corepressor complex when complexed to AGL24 or SVP. Interacts with AGL15 and AGL16 (PubMed:15805477, PubMed:16679456).
Interacts with TT16/AGL32 (PubMed:16080001).

Binary interactions

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for domain, coiled coil.

TypeIDPosition(s)Description
Domain1-61MADS-box
Domain88-178K-box
Coiled coil88-185

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    256
  • Mass (Da)
    30,182
  • Last updated
    2002-06-20 v2
  • Checksum
    01E26DE18CE3478C
MGRGRVQLKRIENKINRQVTFSKRRAGLLKKAHEISVLCDAEVALVVFSHKGKLFEYSTDSCMEKILERYERYSYAERQLIAPESDVNTNWSMEYNRLKAKIELLERNQRHYLGEDLQAMSPKELQNLEQQLDTALKHIRTRKNQLMYESINELQKKEKAIQEQNSMLSKQIKEREKILRAQQEQWDQQNQGHNMPPPLPPQQHQIQHPYMLSHQPSPFLNMGGLYQEDDPMAMRRNDLELTLEPVYNCNLGCFAA

Computationally mapped potential isoform sequences

There are 2 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0A1P8AMJ8A0A1P8AMJ8_ARATHAP1234
A0A1P8AML8A0A1P8AML8_ARATHAP1194

Features

Showing features for sequence conflict.

TypeIDPosition(s)Description
Sequence conflict139in Ref. 5; BAD43696
Sequence conflict184in Ref. 7; AAM28458
Sequence conflict189in Ref. 6; AAM65504
Sequence conflict236in Ref. 1; CAA78909

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
Z16421
EMBL· GenBank· DDBJ
CAA78909.1
EMBL· GenBank· DDBJ
mRNA
AC008262
EMBL· GenBank· DDBJ
AAF27070.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002684
EMBL· GenBank· DDBJ
AEE34887.1
EMBL· GenBank· DDBJ
Genomic DNA
BT004113
EMBL· GenBank· DDBJ
AAO42136.1
EMBL· GenBank· DDBJ
mRNA
BT004951
EMBL· GenBank· DDBJ
AAO50484.1
EMBL· GenBank· DDBJ
mRNA
AK175933
EMBL· GenBank· DDBJ
BAD43696.1
EMBL· GenBank· DDBJ
mRNA
AY087956
EMBL· GenBank· DDBJ
AAM65504.1
EMBL· GenBank· DDBJ
mRNA
AF466771
EMBL· GenBank· DDBJ
AAM28447.1
EMBL· GenBank· DDBJ
Genomic DNA
AF466772
EMBL· GenBank· DDBJ
AAM28448.1
EMBL· GenBank· DDBJ
Genomic DNA
AF466773
EMBL· GenBank· DDBJ
AAM28449.1
EMBL· GenBank· DDBJ
Genomic DNA
AF466774
EMBL· GenBank· DDBJ
AAM28450.1
EMBL· GenBank· DDBJ
Genomic DNA
AF466775
EMBL· GenBank· DDBJ
AAM28451.1
EMBL· GenBank· DDBJ
Genomic DNA
AF466776
EMBL· GenBank· DDBJ
AAM28452.1
EMBL· GenBank· DDBJ
Genomic DNA
AF466777
EMBL· GenBank· DDBJ
AAM28453.1
EMBL· GenBank· DDBJ
Genomic DNA
AF466778
EMBL· GenBank· DDBJ
AAM28454.1
EMBL· GenBank· DDBJ
Genomic DNA
AF466779
EMBL· GenBank· DDBJ
AAM28455.1
EMBL· GenBank· DDBJ
Genomic DNA
AF466780
EMBL· GenBank· DDBJ
AAM28456.1
EMBL· GenBank· DDBJ
Genomic DNA
AF466781
EMBL· GenBank· DDBJ
AAM28457.1
EMBL· GenBank· DDBJ
Genomic DNA
AF466782
EMBL· GenBank· DDBJ
AAM28458.1
EMBL· GenBank· DDBJ
Genomic DNA
AF466783
EMBL· GenBank· DDBJ
AAM28459.1
EMBL· GenBank· DDBJ
Genomic DNA
AF466784
EMBL· GenBank· DDBJ
AAM28460.1
EMBL· GenBank· DDBJ
Genomic DNA
AF466785
EMBL· GenBank· DDBJ
AAM28461.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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