Observational study of gene-disease association gene-environment interaction and pharmacogenomic / toxicogenomic. (HuGE Navigator); This reduced transcription rate for SPR promoter haplotypes 2 and 3 may impact on antidepressant response and susceptibility to bipolar disorder.
Although association of SPR to Parkinson's disease (PD) is not strong enough to support that this is the PARK3 gene this study further implicates a role for SPR in idiopathic PD.
Associated with NEUROLOGICAL: Parkinson's disease., Observational study of gene-disease association. (HuGE Navigator); Potentially modulates the onset of or risk for Parkinson's disease.
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