P33144 · BIMB_EMENI
- ProteinSeparin
- GenebimB
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids2067 (go to sequence)
- Protein existencePredicted
- Annotation score4/5
Function
function
Required for nuclear division. Could function in the mitotic spindle.
Catalytic activity
Features
Showing features for active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 1964 | ||||
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Cellular Component | mitotic spindle | |
Cellular Component | mitotic spindle pole body | |
Cellular Component | nucleus | |
Molecular Function | cysteine-type endopeptidase activity | |
Biological Process | cell division | |
Biological Process | meiotic chromosome separation | |
Biological Process | proteolysis |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameSeparin
- EC number
- Alternative names
Gene names
Organism names
- Strains
- Taxonomic lineageEukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Eurotiomycetes > Eurotiomycetidae > Eurotiales > Aspergillaceae > Aspergillus > Aspergillus subgen. Nidulantes
Accessions
- Primary accessionP33144
- Secondary accessions
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000205902 | 1-2067 | Separin | ||
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Region | 51-91 | Disordered | |||
Compositional bias | 52-91 | Polar residues | |||
Region | 140-167 | Disordered | |||
Compositional bias | 149-167 | Polar residues | |||
Region | 1316-1363 | Disordered | |||
Compositional bias | 1331-1363 | Polar residues | |||
Region | 1449-1478 | Disordered | |||
Domain | 1880-1975 | Peptidase C50 | |||
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length2,067
- Mass (Da)227,831
- Last updated2009-05-26 v2
- Checksum3D711A90E1C0E38E
Sequence caution
Features
Showing features for compositional bias, sequence conflict.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 52-91 | Polar residues | |||
Compositional bias | 149-167 | Polar residues | |||
Sequence conflict | 512 | in Ref. 1; AAA33297 | |||
Sequence conflict | 520 | in Ref. 1; AAA33297 | |||
Compositional bias | 1331-1363 | Polar residues | |||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
M83232 EMBL· GenBank· DDBJ | AAA33297.1 EMBL· GenBank· DDBJ | Genomic DNA | Frameshift | |
AACD01000161 EMBL· GenBank· DDBJ | EAA60576.1 EMBL· GenBank· DDBJ | Genomic DNA | Frameshift | |
BN001303 EMBL· GenBank· DDBJ | CBF78027.1 EMBL· GenBank· DDBJ | Genomic DNA | Frameshift |