P32966 · UVRC_PSEPH
- ProteinUvrABC system protein C
- GeneuvrC
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids607 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Cellular Component | excinuclease repair complex | |
Molecular Function | DNA binding | |
Molecular Function | excinuclease ABC activity | |
Biological Process | nucleotide-excision repair | |
Biological Process | SOS response |
Keywords
- Molecular function
- Biological process
Names & Taxonomy
Protein names
- Recommended nameUvrABC system protein C
- Short namesProtein UvrC
- Alternative names
Gene names
Organism names
- Strains
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Pseudomonadales > Pseudomonadaceae > Pseudomonas
Accessions
- Primary accessionP32966
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000138327 | 1-607 | UvrABC system protein C | |||
Sequence: MTDPFDPSAFLSTCSGRPGVYRMFDSDTRLLYVGKAKNLKSRLASYFRKTGLAPKTAALVGRIAQIETTITANETEALLLEQTLIKEWRPPYNILLRDDKSYPYVFLSDGEFPRFSIHRGAKKQKGKYFGPYPSAGAIRESLSLLQKTFMVRQCEDSYYKNRTRPCLQYQIKRCKAPCVGLVEAEVYAEDVRHSVMFLEGRSNALTDELSAGMEQAASTLDFEKAAELRDQISLLRRVQDQQSMEGGSGDVDVVAAFVNPGGACVHLISVRGGRVLGSKNFFPQVGIEEEVAEVMSAFLGQYFLSSPERDLPSELIVNVVHEDFPALIAAIQELRGRELSISHRVRGTRARWQQLAVTNAEQALSARLANRQHVAARFEALAEVLNLDEPPQRLECYDISHSSGEATVASCVVFGPEGPLKSDYRRYNIEGVTAGDDYAAMHQALTRRFSKLKDGEGKLPDILLVDGGKGQLSMARDVLNELAVPDLILLGVAKGATRKTGFETLYLNDAAHEFTLKGDSPALHLIQQIRDEAHRFAITGHRARRGKTRRTSTLEDVAGVGPKRRRDLLKHFGGLQELSRASIEEIAKAPGISKKLAELIYANLHSE |
Interaction
Subunit
Interacts with UvrB in an incision complex.
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 16-94 | GIY-YIG | ||||
Sequence: GRPGVYRMFDSDTRLLYVGKAKNLKSRLASYFRKTGLAPKTAALVGRIAQIETTITANETEALLLEQTLIKEWRPPYNI | ||||||
Domain | 203-238 | UVR | ||||
Sequence: NALTDELSAGMEQAASTLDFEKAAELRDQISLLRRV |
Sequence similarities
Belongs to the UvrC family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length607
- Mass (Da)67,303
- Last updated1995-11-01 v2
- Checksum179D412EC0B4398C
Features
Showing features for sequence conflict.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Sequence conflict | 3-4 | in Ref. 2; AAA25822 | ||||
Sequence: DP → EQ | ||||||
Sequence conflict | 28 | in Ref. 2; AAA25822 | ||||
Sequence: T → A | ||||||
Sequence conflict | 41 | in Ref. 2; AAA25822 | ||||
Sequence: S → N | ||||||
Sequence conflict | 44 | in Ref. 2; AAA25822 | ||||
Sequence: A → S | ||||||
Sequence conflict | 52 | in Ref. 2; AAA25822 | ||||
Sequence: L → Q | ||||||
Sequence conflict | 61 | in Ref. 2; AAA25822 | ||||
Sequence: G → A | ||||||
Sequence conflict | 111 | in Ref. 2; AAA25822 | ||||
Sequence: E → D | ||||||
Sequence conflict | 123 | in Ref. 2; AAA25822 | ||||
Sequence: K → R | ||||||
Sequence conflict | 184 | in Ref. 2; AAA25822 | ||||
Sequence: A → P | ||||||
Sequence conflict | 211-212 | in Ref. 2; AAA25822 | ||||
Sequence: AG → TA | ||||||
Sequence conflict | 215 | in Ref. 2; AAA25822 | ||||
Sequence: Q → A |