P32966 · UVRC_PSEPH

Function

function

The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytoplasm
Cellular Componentexcinuclease repair complex
Molecular FunctionDNA binding
Molecular Functionexcinuclease ABC activity
Biological Processnucleotide-excision repair
Biological ProcessSOS response

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    UvrABC system protein C
  • Short names
    Protein UvrC
  • Alternative names
    • Excinuclease ABC subunit C

Gene names

    • Name
      uvrC

Organism names

Accessions

  • Primary accession
    P32966

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00001383271-607UvrABC system protein C

Interaction

Subunit

Interacts with UvrB in an incision complex.

Structure

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain16-94GIY-YIG
Domain203-238UVR

Sequence similarities

Belongs to the UvrC family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    607
  • Mass (Da)
    67,303
  • Last updated
    1995-11-01 v2
  • Checksum
    179D412EC0B4398C
MTDPFDPSAFLSTCSGRPGVYRMFDSDTRLLYVGKAKNLKSRLASYFRKTGLAPKTAALVGRIAQIETTITANETEALLLEQTLIKEWRPPYNILLRDDKSYPYVFLSDGEFPRFSIHRGAKKQKGKYFGPYPSAGAIRESLSLLQKTFMVRQCEDSYYKNRTRPCLQYQIKRCKAPCVGLVEAEVYAEDVRHSVMFLEGRSNALTDELSAGMEQAASTLDFEKAAELRDQISLLRRVQDQQSMEGGSGDVDVVAAFVNPGGACVHLISVRGGRVLGSKNFFPQVGIEEEVAEVMSAFLGQYFLSSPERDLPSELIVNVVHEDFPALIAAIQELRGRELSISHRVRGTRARWQQLAVTNAEQALSARLANRQHVAARFEALAEVLNLDEPPQRLECYDISHSSGEATVASCVVFGPEGPLKSDYRRYNIEGVTAGDDYAAMHQALTRRFSKLKDGEGKLPDILLVDGGKGQLSMARDVLNELAVPDLILLGVAKGATRKTGFETLYLNDAAHEFTLKGDSPALHLIQQIRDEAHRFAITGHRARRGKTRRTSTLEDVAGVGPKRRRDLLKHFGGLQELSRASIEEIAKAPGISKKLAELIYANLHSE

Features

Showing features for sequence conflict.

TypeIDPosition(s)Description
Sequence conflict3-4in Ref. 2; AAA25822
Sequence conflict28in Ref. 2; AAA25822
Sequence conflict41in Ref. 2; AAA25822
Sequence conflict44in Ref. 2; AAA25822
Sequence conflict52in Ref. 2; AAA25822
Sequence conflict61in Ref. 2; AAA25822
Sequence conflict111in Ref. 2; AAA25822
Sequence conflict123in Ref. 2; AAA25822
Sequence conflict184in Ref. 2; AAA25822
Sequence conflict211-212in Ref. 2; AAA25822
Sequence conflict215in Ref. 2; AAA25822

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
L29642
EMBL· GenBank· DDBJ
AAA98758.1
EMBL· GenBank· DDBJ
Genomic DNA
M80913
EMBL· GenBank· DDBJ
AAA25822.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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