P32254 · RASS_DICDI
- ProteinRas-like protein rasS
- GenerasS
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids194 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score5/5
Function
function
Ras proteins bind GDP/GTP and possess intrinsic GTPase activity.
Catalytic activity
- GTP + H2O = GDP + phosphate + H+
Features
Showing features for binding site.
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | G protein activity | |
Molecular Function | GDP binding | |
Molecular Function | GTP binding | |
Molecular Function | GTPase activity | |
Molecular Function | phosphatidylinositol 3-kinase binding | |
Biological Process | actin filament organization | |
Biological Process | cell morphogenesis | |
Biological Process | cell motility | |
Biological Process | cortical actin cytoskeleton organization | |
Biological Process | macropinocytosis | |
Biological Process | negative regulation of cell migration | |
Biological Process | negative regulation of cell motility | |
Biological Process | pinocytosis | |
Biological Process | positive regulation of endocytosis | |
Biological Process | positive regulation of macropinocytosis | |
Biological Process | positive regulation of phagocytosis | |
Biological Process | Ras protein signal transduction | |
Biological Process | regulation of cell population proliferation | |
Biological Process | sexual reproduction |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameRas-like protein rasS
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Amoebozoa > Evosea > Eumycetozoa > Dictyostelia > Dictyosteliales > Dictyosteliaceae > Dictyostelium
Accessions
- Primary accessionP32254
- Secondary accessions
Proteomes
Organism-specific databases
Subcellular Location
PTM/Processing
Features
Showing features for chain, modified residue, lipidation, propeptide.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000082664 | 1-191 | Ras-like protein rasS | |||
Sequence: MFNFKLVLVGPGGVGKSCLTIQFIAQKFVDEYDPTLEDSYRKQTTVDGEECLLDIYDTAGQEDFSAVRDQYMRTGEGFLCVYSITYLQSFKEIHRLHNHLLKVKDLDSVPFVLVGNKCDLNEYREVSTAEGEELAKKLNCKFLETSAKERINVSESFYELVREVKKARQSNQHSNSQEQNTDQPIKKKKSC | ||||||
Modified residue | 191 | Cysteine methyl ester | ||||
Sequence: C | ||||||
Lipidation | 191 | S-geranylgeranyl cysteine | ||||
Sequence: C | ||||||
Propeptide | PRO_0000281312 | 192-194 | Removed in mature form | |||
Sequence: NLL |
Keywords
- PTM
Proteomic databases
Structure
Family & Domains
Features
Showing features for motif, region.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Motif | 32-40 | Effector region | ||||
Sequence: YDPTLEDSY | ||||||
Region | 168-194 | Disordered | ||||
Sequence: RQSNQHSNSQEQNTDQPIKKKKSCNLL |
Sequence similarities
Belongs to the small GTPase superfamily. Ras family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Sequence processingThe displayed sequence is further processed into a mature form.
- Length194
- Mass (Da)22,266
- Last updated1993-10-01 v1
- ChecksumAF4C1BD37B938B59
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
Z14134 EMBL· GenBank· DDBJ | CAA78508.1 EMBL· GenBank· DDBJ | mRNA | ||
AAFI02000055 EMBL· GenBank· DDBJ | EAL65646.1 EMBL· GenBank· DDBJ | Genomic DNA |