P31377 · STX8_YEAST

Function

function

t-SNARE which may play a role in determining the specificity of membrane fusion, protein transport and vesicle trafficking within the Golgi/endosomal and plasma membrane/endosomal systems.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytosol
Cellular Componentendomembrane system
Cellular Componentendosome
Cellular Componentendosome membrane
Cellular ComponentGolgi membrane
Cellular ComponentSNARE complex
Molecular FunctionSNAP receptor activity
Molecular FunctionSNARE binding
Biological ProcessGolgi to endosome transport
Biological ProcessGolgi to vacuole transport
Biological ProcessGolgi vesicle fusion to target membrane
Biological Processintracellular protein transport
Biological Processvesicle docking
Biological Processvesicle fusion

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Syntaxin-8
  • Alternative names
    • SNARE protein related to mammalian syntaxin 8
    • ULP1-interacting protein 2

Gene names

    • Name
      SYN8
    • Synonyms
      UIP2
    • ORF names
      FUN34
    • Ordered locus names
      YAL014C

Organism names

Accessions

  • Primary accession
    P31377
  • Secondary accessions
    • D6VPK4

Proteomes

Organism-specific databases

Subcellular Location

Features

Showing features for topological domain, transmembrane.

TypeIDPosition(s)Description
Topological domain1-234Cytoplasmic
Transmembrane235-255Helical; Anchor for type IV membrane protein

Keywords

PTM/Processing

Features

Showing features for chain, lipidation.

TypeIDPosition(s)Description
ChainPRO_00002102811-255Syntaxin-8
Lipidation238S-palmitoyl cysteine

Post-translational modification

Palmitoylated by SWF1.

Keywords

Proteomic databases

PTM databases

Interaction

Subunit

Interacts with PEP12, VTI1 and the SNC SNARE complex proteins.
View interactors in UniProtKB
View CPX-5421 in Complex Portal

Protein-protein interaction databases

Miscellaneous

Structure

Family & Domains

Features

Showing features for region, compositional bias, domain.

TypeIDPosition(s)Description
Region110-154Disordered
Compositional bias132-154Polar residues
Domain164-228t-SNARE coiled-coil homology

Sequence similarities

Belongs to the syntaxin family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    255
  • Mass (Da)
    29,049
  • Last updated
    2003-05-16 v2
  • Checksum
    7631FB672F8E55D6
MDVLKLGYELDQLSDLVEERTRLVSVLKLAPTSNDNVTLKRQLGSILELLQKCAPNDELISRYNTILDKIPDTAVDKELYRFQQQVARNTDEVSKESLKKVRFKNDDELTVMYKDDDEQDEESPLPSTHTPYKDEPLQSQLQSQSQPQPPQPMVSNQELFINQQQQLLEQDSHLGALSQSIGRTHDISLDLNNEIVSQNDSLLVDLENLIDNNGRNLNRASRSMHGFNNSRFKDNGNCVIILVLIVVLLLLLLVL

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias132-154Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AY205237
EMBL· GenBank· DDBJ
AAO46883.1
EMBL· GenBank· DDBJ
Genomic DNA
AY205236
EMBL· GenBank· DDBJ
AAO22142.1
EMBL· GenBank· DDBJ
Genomic DNA
L05146
EMBL· GenBank· DDBJ
AAC04943.2
EMBL· GenBank· DDBJ
Genomic DNA
BK006935
EMBL· GenBank· DDBJ
DAA06974.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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