P31374 · PSK1_YEAST
- ProteinSerine/threonine-protein kinase PSK1
- GenePSK1
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids1356 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score5/5
Variants
Variant ID(s) | Position(s) | Change | Description | Clinical significance | Provenance | ||
---|---|---|---|---|---|---|---|
s01-120278 | 18 | K>R | SGRP | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.37) Somatic: No Accession: I:g.120277A>G Codon: AAG/AGG Consequence type: missense Cytogenetic band: Genomic location: I:g.120277A>G Locations: - p.Lys18Arg (Ensembl:YAL017W_mRNA) - c.53A>G (Ensembl:YAL017W_mRNA) Source type: large scale study Cross-references: - SGRP: s01-120278 | |||||||
s01-120379 | 52 | E>K | SGRP | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.63) Somatic: No Accession: I:g.120378G>A Codon: GAA/AAA Consequence type: missense Cytogenetic band: Genomic location: I:g.120378G>A Locations: - p.Glu52Lys (Ensembl:YAL017W_mRNA) - c.154G>A (Ensembl:YAL017W_mRNA) Source type: large scale study Cross-references: - SGRP: s01-120379 | |||||||
s01-120406 | 61 | V>I | SGRP | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.35) Somatic: No Accession: I:g.120405G>A Codon: GTT/ATT Consequence type: missense Cytogenetic band: Genomic location: I:g.120405G>A Locations: - p.Val61Ile (Ensembl:YAL017W_mRNA) - c.181G>A (Ensembl:YAL017W_mRNA) Source type: large scale study Cross-references: - SGRP: s01-120406 | |||||||
s01-120536 | 104 | S>F | SGRP | ||||
Consequence: missense Predictions: - SIFT: deleterious (0.03) Somatic: No Accession: I:g.120535C>T Codon: TCT/TTT Consequence type: missense Cytogenetic band: Genomic location: I:g.120535C>T Locations: - p.Ser104Phe (Ensembl:YAL017W_mRNA) - c.311C>T (Ensembl:YAL017W_mRNA) Source type: large scale study Cross-references: - SGRP: s01-120536 | |||||||
s01-120896 | 224 | A>V | SGRP | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.44) Somatic: No Accession: I:g.120895C>T Codon: GCA/GTA Consequence type: missense Cytogenetic band: Genomic location: I:g.120895C>T Locations: - p.Ala224Val (Ensembl:YAL017W_mRNA) - c.671C>T (Ensembl:YAL017W_mRNA) Source type: large scale study Cross-references: - SGRP: s01-120896 | |||||||
s01-120912 | 229 | L>F | SGRP | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.29) Somatic: No Accession: I:g.120911A>C Codon: TTA/TTC Consequence type: missense Cytogenetic band: Genomic location: I:g.120911A>C Locations: - p.Leu229Phe (Ensembl:YAL017W_mRNA) - c.687A>C (Ensembl:YAL017W_mRNA) Source type: large scale study Cross-references: - SGRP: s01-120912 | |||||||
s01-120926 | 234 | P>Q | SGRP | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.57) Somatic: No Accession: I:g.120925C>A Codon: CCG/CAG Consequence type: missense Cytogenetic band: Genomic location: I:g.120925C>A Locations: - p.Pro234Gln (Ensembl:YAL017W_mRNA) - c.701C>A (Ensembl:YAL017W_mRNA) Source type: large scale study Cross-references: - SGRP: s01-120926 | |||||||
s01-120940 | 239 | F>L | SGRP | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.7) Somatic: No Accession: I:g.120939T>C Codon: TTC/CTC Consequence type: missense Cytogenetic band: Genomic location: I:g.120939T>C Locations: - p.Phe239Leu (Ensembl:YAL017W_mRNA) - c.715T>C (Ensembl:YAL017W_mRNA) Source type: large scale study Cross-references: - SGRP: s01-120940 | |||||||
s01-120965 | 247 | S>C | SGRP | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.09) Somatic: No Accession: I:g.120964C>G Codon: TCT/TGT Consequence type: missense Cytogenetic band: Genomic location: I:g.120964C>G Locations: - p.Ser247Cys (Ensembl:YAL017W_mRNA) - c.740C>G (Ensembl:YAL017W_mRNA) Source type: large scale study Cross-references: - SGRP: s01-120965 | |||||||
s01-121454 | 410 | G>E | SGRP | ||||
Consequence: missense Predictions: - SIFT: tolerated (1) Somatic: No Accession: I:g.121453G>A Codon: GGA/GAA Consequence type: missense Cytogenetic band: Genomic location: I:g.121453G>A Locations: - p.Gly410Glu (Ensembl:YAL017W_mRNA) - c.1229G>A (Ensembl:YAL017W_mRNA) Source type: large scale study Cross-references: - SGRP: s01-121454 | |||||||
s01-121508 | 428 | T>I | SGRP | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.3) Somatic: No Accession: I:g.121507C>T Codon: ACA/ATA Consequence type: missense Cytogenetic band: Genomic location: I:g.121507C>T Locations: - p.Thr428Ile (Ensembl:YAL017W_mRNA) - c.1283C>T (Ensembl:YAL017W_mRNA) Source type: large scale study Cross-references: - SGRP: s01-121508 | |||||||
s01-121561 | 446 | G>S | SGRP | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.22) Somatic: No Accession: I:g.121560G>A Codon: GGC/AGC Consequence type: missense Cytogenetic band: Genomic location: I:g.121560G>A Locations: - p.Gly446Ser (Ensembl:YAL017W_mRNA) - c.1336G>A (Ensembl:YAL017W_mRNA) Source type: large scale study Cross-references: - SGRP: s01-121561 | |||||||
s01-121825 | 534 | E>K | SGRP | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.16) Somatic: No Accession: I:g.121824G>A Codon: GAA/AAA Consequence type: missense Cytogenetic band: Genomic location: I:g.121824G>A Locations: - p.Glu534Lys (Ensembl:YAL017W_mRNA) - c.1600G>A (Ensembl:YAL017W_mRNA) Source type: large scale study Cross-references: - SGRP: s01-121825 | |||||||
s01-121829 | 535 | T>K | SGRP | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.86) Somatic: No Accession: I:g.121828C>A Codon: ACA/AAA Consequence type: missense Cytogenetic band: Genomic location: I:g.121828C>A Locations: - p.Thr535Lys (Ensembl:YAL017W_mRNA) - c.1604C>A (Ensembl:YAL017W_mRNA) Source type: large scale study Cross-references: - SGRP: s01-121829 | |||||||
s01-121950 | 575 | D>E | SGRP | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.11) Somatic: No Accession: I:g.121949T>A Codon: GAT/GAA Consequence type: missense Cytogenetic band: Genomic location: I:g.121949T>A Locations: - p.Asp575Glu (Ensembl:YAL017W_mRNA) - c.1725T>A (Ensembl:YAL017W_mRNA) Source type: large scale study Cross-references: - SGRP: s01-121950 | |||||||
s01-121957 | 578 | A>T | SGRP | ||||
Consequence: missense Predictions: - SIFT: deleterious (0.01) Somatic: No Accession: I:g.121956G>A Codon: GCC/ACC Consequence type: missense Cytogenetic band: Genomic location: I:g.121956G>A Locations: - p.Ala578Thr (Ensembl:YAL017W_mRNA) - c.1732G>A (Ensembl:YAL017W_mRNA) Source type: large scale study Cross-references: - SGRP: s01-121957 | |||||||
s01-121958 | 578 | A>V | SGRP | ||||
Consequence: missense Predictions: - SIFT: tolerated (1) Somatic: No Accession: I:g.121957C>T Codon: GCC/GTC Consequence type: missense Cytogenetic band: Genomic location: I:g.121957C>T Locations: - p.Ala578Val (Ensembl:YAL017W_mRNA) - c.1733C>T (Ensembl:YAL017W_mRNA) Source type: large scale study Cross-references: - SGRP: s01-121958 | |||||||
s01-122156 | 644 | D>G | SGRP | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.42) Somatic: No Accession: I:g.122155A>G Codon: GAT/GGT Consequence type: missense Cytogenetic band: Genomic location: I:g.122155A>G Locations: - p.Asp644Gly (Ensembl:YAL017W_mRNA) - c.1931A>G (Ensembl:YAL017W_mRNA) Source type: large scale study Cross-references: - SGRP: s01-122156 | |||||||
s01-122183 | 653 | L>Q | SGRP | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.57) Somatic: No Accession: I:g.122182T>A Codon: CTG/CAG Consequence type: missense Cytogenetic band: Genomic location: I:g.122182T>A Locations: - p.Leu653Gln (Ensembl:YAL017W_mRNA) - c.1958T>A (Ensembl:YAL017W_mRNA) Source type: large scale study Cross-references: - SGRP: s01-122183 | |||||||
s01-122192 | 656 | S>L | SGRP | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.22) Somatic: No Accession: I:g.122191C>T Codon: TCG/TTG Consequence type: missense Cytogenetic band: Genomic location: I:g.122191C>T Locations: - p.Ser656Leu (Ensembl:YAL017W_mRNA) - c.1967C>T (Ensembl:YAL017W_mRNA) Source type: large scale study Cross-references: - SGRP: s01-122192 | |||||||
s01-122203 | 660 | S>T | SGRP | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.59) Somatic: No Accession: I:g.122202T>A Codon: TCG/ACG Consequence type: missense Cytogenetic band: Genomic location: I:g.122202T>A Locations: - p.Ser660Thr (Ensembl:YAL017W_mRNA) - c.1978T>A (Ensembl:YAL017W_mRNA) Source type: large scale study Cross-references: - SGRP: s01-122203 | |||||||
s01-122299 | 692 | V>L | SGRP | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.8) Somatic: No Accession: I:g.122298G>T Codon: GTA/TTA Consequence type: missense Cytogenetic band: Genomic location: I:g.122298G>T Locations: - p.Val692Leu (Ensembl:YAL017W_mRNA) - c.2074G>T (Ensembl:YAL017W_mRNA) Source type: large scale study Cross-references: - SGRP: s01-122299 | |||||||
s01-122332 | 703 | P>A | SGRP | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.43) Somatic: No Accession: I:g.122331C>G Codon: CCC/GCC Consequence type: missense Cytogenetic band: Genomic location: I:g.122331C>G Locations: - p.Pro703Ala (Ensembl:YAL017W_mRNA) - c.2107C>G (Ensembl:YAL017W_mRNA) Source type: large scale study Cross-references: - SGRP: s01-122332 | |||||||
s01-122340 | 705 | K>N | SGRP | ||||
Consequence: missense Predictions: - SIFT: deleterious (0.01) Somatic: No Accession: I:g.122339A>T Codon: AAA/AAT Consequence type: missense Cytogenetic band: Genomic location: I:g.122339A>T Locations: - p.Lys705Asn (Ensembl:YAL017W_mRNA) - c.2115A>T (Ensembl:YAL017W_mRNA) Source type: large scale study Cross-references: - SGRP: s01-122340 | |||||||
s01-122408 | 728 | A>V | SGRP | ||||
Consequence: missense Predictions: - SIFT: deleterious (0) Somatic: No Accession: I:g.122407C>T Codon: GCG/GTG Consequence type: missense Cytogenetic band: Genomic location: I:g.122407C>T Locations: - p.Ala728Val (Ensembl:YAL017W_mRNA) - c.2183C>T (Ensembl:YAL017W_mRNA) Source type: large scale study Cross-references: - SGRP: s01-122408 | |||||||
s01-122452 | 743 | H>Y | SGRP | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.05) Somatic: No Accession: I:g.122451C>T Codon: CAC/TAC Consequence type: missense Cytogenetic band: Genomic location: I:g.122451C>T Locations: - p.His743Tyr (Ensembl:YAL017W_mRNA) - c.2227C>T (Ensembl:YAL017W_mRNA) Source type: large scale study Cross-references: - SGRP: s01-122452 | |||||||
s01-122941 | 906 | S>P | SGRP | ||||
Consequence: missense Predictions: - SIFT: deleterious (0.02) Somatic: No Accession: I:g.122940T>C Codon: TCT/CCT Consequence type: missense Cytogenetic band: Genomic location: I:g.122940T>C Locations: - p.Ser906Pro (Ensembl:YAL017W_mRNA) - c.2716T>C (Ensembl:YAL017W_mRNA) Source type: large scale study Cross-references: - SGRP: s01-122941 | |||||||
s01-123337 | 1038 | E>K | SGRP | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.56) Somatic: No Accession: I:g.123336G>A Codon: GAA/AAA Consequence type: missense Cytogenetic band: Genomic location: I:g.123336G>A Locations: - p.Glu1038Lys (Ensembl:YAL017W_mRNA) - c.3112G>A (Ensembl:YAL017W_mRNA) Source type: large scale study Cross-references: - SGRP: s01-123337 | |||||||
s01-123383 | 1053 | A>V | SGRP | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.34) Somatic: No Accession: I:g.123382C>T Codon: GCG/GTG Consequence type: missense Cytogenetic band: Genomic location: I:g.123382C>T Locations: - p.Ala1053Val (Ensembl:YAL017W_mRNA) - c.3158C>T (Ensembl:YAL017W_mRNA) Source type: large scale study Cross-references: - SGRP: s01-123383 | |||||||
s01-123406 | 1061 | G>R | SGRP | ||||
Consequence: missense Predictions: - SIFT: tolerated - low confidence (0.26) Somatic: No Accession: I:g.123405G>A Codon: GGA/AGA Consequence type: missense Cytogenetic band: Genomic location: I:g.123405G>A Locations: - p.Gly1061Arg (Ensembl:YAL017W_mRNA) - c.3181G>A (Ensembl:YAL017W_mRNA) Source type: large scale study Cross-references: - SGRP: s01-123406 | |||||||
s01-123595 | 1124 | I>F | SGRP | ||||
Consequence: missense Predictions: - SIFT: deleterious (0) Somatic: No Accession: I:g.123594A>T Codon: ATT/TTT Consequence type: missense Cytogenetic band: Genomic location: I:g.123594A>T Locations: - p.Ile1124Phe (Ensembl:YAL017W_mRNA) - c.3370A>T (Ensembl:YAL017W_mRNA) Source type: large scale study Cross-references: - SGRP: s01-123595 | |||||||
s01-123613 | 1130 | E>K | SGRP | ||||
Consequence: missense Predictions: - SIFT: deleterious (0) Somatic: No Accession: I:g.123612G>A Codon: GAA/AAA Consequence type: missense Cytogenetic band: Genomic location: I:g.123612G>A Locations: - p.Glu1130Lys (Ensembl:YAL017W_mRNA) - c.3388G>A (Ensembl:YAL017W_mRNA) Source type: large scale study Cross-references: - SGRP: s01-123613 | |||||||
s01-123856 | 1211 | F>L | SGRP | ||||
Consequence: missense Predictions: - SIFT: deleterious (0) Somatic: No Accession: I:g.123855T>C Codon: TTC/CTC Consequence type: missense Cytogenetic band: Genomic location: I:g.123855T>C Locations: - p.Phe1211Leu (Ensembl:YAL017W_mRNA) - c.3631T>C (Ensembl:YAL017W_mRNA) Source type: large scale study Cross-references: - SGRP: s01-123856 | |||||||
s01-124060 | 1279 | P>S | SGRP | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.1) Somatic: No Accession: I:g.124059C>T Codon: CCT/TCT Consequence type: missense Cytogenetic band: Genomic location: I:g.124059C>T Locations: - p.Pro1279Ser (Ensembl:YAL017W_mRNA) - c.3835C>T (Ensembl:YAL017W_mRNA) Source type: large scale study Cross-references: - SGRP: s01-124060 | |||||||
s01-124190 | 1322 | E>G | SGRP | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.4) Somatic: No Accession: I:g.124189A>G Codon: GAA/GGA Consequence type: missense Cytogenetic band: Genomic location: I:g.124189A>G Locations: - p.Glu1322Gly (Ensembl:YAL017W_mRNA) - c.3965A>G (Ensembl:YAL017W_mRNA) Source type: large scale study Cross-references: - SGRP: s01-124190 |