P31101 · HCP_NITV2

Function

function

Catalyzes the reduction of hydroxylamine to form NH3 and H2O.

Caution

Was originally thought to contain a [6Fe-6S] cluster as indicated.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
[4Fe-4S] cluster (UniProtKB | Rhea| CHEBI:49883 )

Note: Binds 1 spin-admixed [4Fe-4S] cluster.
hybrid [4Fe-2O-2S] cluster (UniProtKB | Rhea| CHEBI:60519 )

Note: Binds 1 hybrid [4Fe-2O-2S] cluster.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site3[4Fe-4S] cluster (UniProtKB | ChEBI)
Binding site6[4Fe-4S] cluster (UniProtKB | ChEBI)
Binding site15[4Fe-4S] cluster (UniProtKB | ChEBI)
Binding site21[4Fe-4S] cluster (UniProtKB | ChEBI)
Binding site244hybrid [4Fe-2O-2S] cluster (UniProtKB | ChEBI)
Binding site268hybrid [4Fe-2O-2S] cluster (UniProtKB | ChEBI)
Binding site312hybrid [4Fe-2O-2S] cluster (UniProtKB | ChEBI)
Binding site406hybrid [4Fe-2O-2S] cluster (UniProtKB | ChEBI); via persulfide group
Binding site434hybrid [4Fe-2O-2S] cluster (UniProtKB | ChEBI)
Binding site459hybrid [4Fe-2O-2S] cluster (UniProtKB | ChEBI)
Binding site494hybrid [4Fe-2O-2S] cluster (UniProtKB | ChEBI)
Binding site496hybrid [4Fe-2O-2S] cluster (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Function4 iron, 4 sulfur cluster binding
Molecular Functionhydroxylamine reductase activity
Molecular Functionmetal ion binding

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Hydroxylamine reductase
  • EC number
  • Alternative names
    • Hybrid-cluster protein
      (HCP
      )
    • Prismane protein

Gene names

    • Name
      hcp
    • Ordered locus names
      DVU_2013

Organism names

Accessions

  • Primary accession
    P31101

Proteomes

Subcellular Location

Keywords

Phenotypes & Variants

Chemistry

PTM/Processing

Features

Showing features for chain, modified residue.

TypeIDPosition(s)Description
ChainPRO_00001516671-553Hydroxylamine reductase
Modified residue406Cysteine persulfide

Proteomic databases

Interaction

Subunit

Monomer.

Protein-protein interaction databases

Family & Domains

Sequence similarities

Belongs to the HCP family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    553
  • Mass (Da)
    59,979
  • Last updated
    1998-12-15 v2
  • Checksum
    DC3FFC3992B51869
MFCFQCQETAKNTGCTVKGMCGKPEETANLQDLLIFVLRGIAIYGEKLKELGQPDRSNDDFVLQGLFATITNANWDDARFEAMISEGLARRDKLRNAFLAVYKAKNGKDFSEPLPEAATWTGDSTAFAEKAKSVGILATENEDVRSLRELLIIGLKGVAAYAEHAAVLGFRKTEIDEFMLEALASTTKDLSVDEMVALVMKAGGMAVTTMALLDEANTTTYGNPEITQVNIGVGKNPGILISGHDLKDMAELLKQTEGTGVDVYTHGEMLPANYYPAFKKYPHFVGNYGGSWWQQNPEFESFNGPILLTTNCLVPLKKENTYLDRLYTTGVVGYEGAKHIADRPAGGAKDFSALIAQAKKCPPPVEIETGSIVGGFAHHQVLALADKVVEAVKSGAIKRFVVMAGCDGRQKSRSYYTEVAENLPKDTVILTAGCAKYRYNKLNLGDIGGIPRVLDAGQCNDSYSLAVIALKLKEVFGLDDINDLPVSYDIAWYEQKAVAVLLALLFLGVKGIRLGPTLPAFLSPNVAKVLVENFNIKPIGTVQDDIAAMMAGK

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
Z11707
EMBL· GenBank· DDBJ
CAA77767.1
EMBL· GenBank· DDBJ
Genomic DNA
AE017285
EMBL· GenBank· DDBJ
AAS96488.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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