P31101 · HCP_NITV2
- ProteinHydroxylamine reductase
- Genehcp
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids553 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score4/5
Function
function
Catalyzes the reduction of hydroxylamine to form NH3 and H2O.
Catalytic activity
- A + H2O + NH4+ = AH2 + H+ + hydroxylamine
Cofactor
Protein has several cofactor binding sites:
Note: Binds 1 spin-admixed [4Fe-4S] cluster.
Note: Binds 1 hybrid [4Fe-2O-2S] cluster.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 3 | [4Fe-4S] cluster (UniProtKB | ChEBI) | ||||
Sequence: C | ||||||
Binding site | 6 | [4Fe-4S] cluster (UniProtKB | ChEBI) | ||||
Sequence: C | ||||||
Binding site | 15 | [4Fe-4S] cluster (UniProtKB | ChEBI) | ||||
Sequence: C | ||||||
Binding site | 21 | [4Fe-4S] cluster (UniProtKB | ChEBI) | ||||
Sequence: C | ||||||
Binding site | 244 | hybrid [4Fe-2O-2S] cluster (UniProtKB | ChEBI) | ||||
Sequence: H | ||||||
Binding site | 268 | hybrid [4Fe-2O-2S] cluster (UniProtKB | ChEBI) | ||||
Sequence: E | ||||||
Binding site | 312 | hybrid [4Fe-2O-2S] cluster (UniProtKB | ChEBI) | ||||
Sequence: C | ||||||
Binding site | 406 | hybrid [4Fe-2O-2S] cluster (UniProtKB | ChEBI); via persulfide group | ||||
Sequence: C | ||||||
Binding site | 434 | hybrid [4Fe-2O-2S] cluster (UniProtKB | ChEBI) | ||||
Sequence: C | ||||||
Binding site | 459 | hybrid [4Fe-2O-2S] cluster (UniProtKB | ChEBI) | ||||
Sequence: C | ||||||
Binding site | 494 | hybrid [4Fe-2O-2S] cluster (UniProtKB | ChEBI) | ||||
Sequence: E | ||||||
Binding site | 496 | hybrid [4Fe-2O-2S] cluster (UniProtKB | ChEBI) | ||||
Sequence: K |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | 4 iron, 4 sulfur cluster binding | |
Molecular Function | hydroxylamine reductase activity | |
Molecular Function | metal ion binding |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameHydroxylamine reductase
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Thermodesulfobacteriota > Desulfovibrionia > Desulfovibrionales > Desulfovibrionaceae > Nitratidesulfovibrio
Accessions
- Primary accessionP31101
Proteomes
Subcellular Location
Phenotypes & Variants
Chemistry
PTM/Processing
Features
Showing features for chain, modified residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000151667 | 1-553 | Hydroxylamine reductase | |||
Sequence: MFCFQCQETAKNTGCTVKGMCGKPEETANLQDLLIFVLRGIAIYGEKLKELGQPDRSNDDFVLQGLFATITNANWDDARFEAMISEGLARRDKLRNAFLAVYKAKNGKDFSEPLPEAATWTGDSTAFAEKAKSVGILATENEDVRSLRELLIIGLKGVAAYAEHAAVLGFRKTEIDEFMLEALASTTKDLSVDEMVALVMKAGGMAVTTMALLDEANTTTYGNPEITQVNIGVGKNPGILISGHDLKDMAELLKQTEGTGVDVYTHGEMLPANYYPAFKKYPHFVGNYGGSWWQQNPEFESFNGPILLTTNCLVPLKKENTYLDRLYTTGVVGYEGAKHIADRPAGGAKDFSALIAQAKKCPPPVEIETGSIVGGFAHHQVLALADKVVEAVKSGAIKRFVVMAGCDGRQKSRSYYTEVAENLPKDTVILTAGCAKYRYNKLNLGDIGGIPRVLDAGQCNDSYSLAVIALKLKEVFGLDDINDLPVSYDIAWYEQKAVAVLLALLFLGVKGIRLGPTLPAFLSPNVAKVLVENFNIKPIGTVQDDIAAMMAGK | ||||||
Modified residue | 406 | Cysteine persulfide | ||||
Sequence: C |
Proteomic databases
Interaction
Structure
Sequence
- Sequence statusComplete
- Length553
- Mass (Da)59,979
- Last updated1998-12-15 v2
- ChecksumDC3FFC3992B51869
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
Z11707 EMBL· GenBank· DDBJ | CAA77767.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AE017285 EMBL· GenBank· DDBJ | AAS96488.1 EMBL· GenBank· DDBJ | Genomic DNA |