P30427 · PLEC_RAT
- ProteinPlectin
- GenePlec
- StatusUniProtKB reviewed (Swiss-Prot)
- Organism
- Amino acids4687 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score5/5
Function
function
Interlinks intermediate filaments with microtubules and microfilaments and anchors intermediate filaments to desmosomes or hemidesmosomes. May be involved not only in the cross-linking and stabilization of cytoskeletal intermediate filaments network, but also in the regulation of their dynamics.
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Keywords
- Molecular function
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePlectin
- Short namesPCN; PLTN
- Alternative names
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Rattus
Accessions
- Primary accessionP30427
- Secondary accessions
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Note: Localized to the cortex of myotube podosomes.
Keywords
- Cellular component
PTM/Processing
Features
Showing features for chain, modified residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000078137 | 1-4687 | Plectin | |||
Sequence: MVAGMLMPLDQLRAIYEVLFREGVMVAKKDRRPRSLHPHVPGVTNLQVMRAMTSLKARGLVRETFAWCHFYWYLTNEGIDHLRQYLHLPPEIVPASLQRVRRPVAMVMPARRRSPHVQTMQGPLGCPPKRGPLPAEDPAREERQVYRRKEREEGAPETPVVSATIVGTLARPGPEPTPATDERDRVQKKTSTKWVNKHLIKAQRHISDLYEDLRDGHNLISLLEVLSGDSLPREKGRMRFHKLQNVQIALDYLRHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFKISDIQVSGQSEDMTAKEKLLLWSQRMVEGYQGLRCDNFTTSWRDGRLFNAIIHRHKPMLIDMNKVYRQTNLENLDQAFSVAERDLGVTRLLDPEDVDVPQPDEKSIITYVSSLYDAMPRVPGAQDGVRANELQLRWQEYRELVLLLLQWIRHHTAAFEERKFPSSFEEIEILWCQFLKFKETELPAKEADKNRSKGIYQSLEGAVQAGQLKIPPGYHPLDVEKEWGKLHVAILEREKQLRSEFERLECLQRIVSKLQMEAGLCEEQLYQADSLLQSDIRLLASGKAAQRAGEVERDLDKADGMIRLLFNDVQTLKDGRHPQGEQMYRRVYRLHERLVAIRTEYNLRLKAGVGAPVTQVTLQSTQRRPELEDSTLRYLHDLLAWVEENQRRIDGAEWGVDLPSVEAQLGSHRGMHQSIEEFRAKIERARNDESQLSPATRGAYRDCLGRLDLQYAKLLNSSKARLRSLESLHGFVAAATKELMWLNEKEEEEVGFDWSDRNTNMAAKKESYSALMRELEMKEKKIKEIQNTGDRLLREDHPARPTVESFQAALQTQWSWMLQLCCCIEAHLKENTAYFQFFSDVREAEEQLQKLQETLRRKYSCDRSITVTRLEDLLQDAQDEKEQLNEYKGHLSGLAKRAKAIVQLKPRNPAHPVRGHVPLLAVCDYKQVEVTVHKGDQCQLVGPAQPFHWKVLSSSGSEAAVPSVCFLVPPPNQEAQEAVARLEAQHQALVTLWHQLHVDMKSLLAWQSLNRDIQLIRSWSLVTFRTLKPEEQRQALRNLELHYQAFLRDSQDAGGFGPEDRLVAEREYGSCSRHYQQLLQSLEQGEQEESRCQRCISELKDIRLQLEACETRTVHRLRLPLDKDPARECAQRIAEQQKAQAEVEGLGKGVARLSAEAEKVLALPEPSPAAPTLRSELELTLGKLEQVRSLSAIYLEKLKTISLVIRSTQGAEEVLKTHEEHLKEAQAVPATLQELEVTKASLKKLRAQAEAQQPVFNTLRDELRGAQEVGERLQQRHGERDVEVERWRERVTQLLERWQAVLAQTDVRQRELEQLGRQLRYYRESADPLSSWLQDAKSRQEQIQAVPIANSQAAREQLRQEKALLEEIERHGEKVEECQKFAKQYINAIKDYELQLITYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTRYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAELEARELQRRMQEEVTRREEAAVDAQQQKRSIQEELQHLRQSSEAEIQAKAQQVEAAERSRMRIEEEIRVVRLQLETTERQRGGAEDELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEAELALRVKAEAEAAREKQRALQALDELKLQAEEAERWLCQAEAERARQVQVALETAQRSAEVELQSKRPSFAEKTAQLERTLQEEHVTVTQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQADAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLTEGTAQQRLAAEQELIRLRAETEQGEHQRQLLEEELARLQHEATAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEARRHRELAEEDAARQRAEADGVLTEKLAAISEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASESELERQKGLVEDTLRQRRQVEEEIMALKASFEKAAAGKAELELELGRIRSNAEDTMRSKELAEQEAARQRQLAAEEEQRRREAEERVQRSLAAEEEAARQRKVALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFVVQQREEELQQTLQQEQNMLERLRSEAEAARRAAEEAEEAREQAEREAAQSRKQVEEAERLKQSAEEQAQAQAQAQAAAEKLRKEAEQEAARRAQAEQAALKQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKSILDEELQRLKAEVTEAARQRSQVEEELFSVRVQMEELGKLKARIEAENRALILRDKDNTQRFLEEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQADKEQMAQQLVEETQGFQRTLEAERQRQLEMSAEAERLKLRMAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDQDAERLREAIAELEREKEKLKQEAKLLQLKSEEMQTVQQEQILQETQALQKSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAKQLQEEQQRQQQQMEQEKQELVASMEEARRRQREAEEGVRRKQEELQRLEQQRQQQEKLLAEENQRLRERLQRLEEEHRAALAHSEEIATSQAAATKALPNGRDALDGPSMEAEPEYTFEGLRQKVPAQQLQEAGILSMEELQRLTQGHTTVAELTQREDVRHYLKGGSSIAGLLLKPTNEKLSVYTALQRQLLSPGTALILLEAQAASGFLLDPVRNRRLTVNEAVKEGVVGPELHHKLLSAERAVTGYKDPYTGEQISLFQAMKKDLIVRDHGIRLLEAQIATGGIIDPVHSHRVPVDVAYQRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLRLLPLTDKAAKGGELVYTDTEARDVFEKATVSAPFGKFQGKTVTIWEIINSEYFTAEQRRDLLRQFRTGRITVEKIIKIVITVVEEHERKGQLCFEGLRALVPAAELLDSGVISHEVYQQLQRGERSVREVAEADEVRQALRGTSVIAGVWLEEAGQKLSIYEALRRDLLQPEVAVALLEAQAGTGHIIDPATSARLTVDEAVRAGLVGPEMHEKLLSAEKAVTGYRDPYSGQSVSLFQALKKGLIPREQGLRLLDAQLSTGGIVDPSKSHRVPLDVAYARGYLDKETNRALTSPRDDARVYLDPSTREPVTYSQLQQRCRSDQLTGLSLLPLSEKAVRARQEEVYSELQARETLEKAKVEVPVGGFKGRALTVWELISSEYFTEEQRQELLRQFRTGKVTVEKVIKILITIVEEVETQRQERLSFSGLRAPVPASELLASKILSRTQFEQLKDGKTSVKDLSEVGSVRTLLQGSGCLAGIYLEDSKEKVTIYEAMRRGLLRASTATLLLEAQAATGFLVDPVRNQRLYVHEAVKAGVVGPELHEKLLSAEKAVTGYKDPYSGSTISLFQAMKKGLVLRDHAIRLLEAQIATGGIIDPVHSHRLPVDVAYQRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLRLLPLRGAEKTEVVETTQVYTEEETRRAFEETQIDIPGGGSHGGSSMSLWEVMQSDMIPEDQRARLMADFQAGRVTKERMIIIIIEIIEKTEIIRQQNLASYDYVRRRLTAEDLYEARIISLETYNLFREGTKSLREVLEMESAWRYLYGTGSVAGVYLPGSRQTLTIYQALKKGLLSAEVARLLLEAQAATGFLLDPVKGERLTVDEAVRKGLVGPELHDRLLSAERAVTGYRDPYTEQPISLFQAMKKELIPAEEALRLLDAQLATGGIVDPRLGFHLPLEVAYQRGYLNKDTHDQLSEPSEVRSYVDPSTDERLSYTQLLKRCRRDDNSGQMLLPLSDARKLTFRGLRKQITVEELVRSQVMDEATALQLQEGLTSIEEVTKNLQKFLEGTSCIAGVFVDATKERLSVYQAMKKGIIRPGTAFELLEAQAATGYVIDPIKGLKLTVEEAVRMGIVGPEFKDKLLSAERAVTGYKDPYSGKLISLFQAMKKGLILKDHGIRLLEAQIATGGIIDPEESHRLPVEVAYKRGLFDEEMNEILTDPSDDTKGFFDPNTEENLTYLQLMERCITDPQTGLCLLPLKEKKRERKTSSKSSVRKRRVVIVDPETGKEMSVYEAYRKGLIDHQTYLELSEQECEWEEITISSSDGVVKSMIIDRRSGRQYDIGDAITKNLIDRSALDQYRAGTLSITEFADMLSGNAGGFRSRSSSVGSSSSYPISSAVPRTQLASWSDPTEETGPVAGILDTETLEKVSITEAMHRNLVDNITGQRLLEAQACTGGIIDPSTGERFPVTEAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAAQALKKGWLYYEAGQRFLEVQYLTGGLIEPDTPGRVSLDEALQRGTVDARTAQKLRDVSAYSKYLTCPKTKLKISYKDALDRSMVEEGTGLRLLEAAAQSSKGYYSPYSVSGSGSTAGSRTGSRTGSRAGSRRGSFDATGSGFSMTFSSSSYSSSGYGRRYASGPSASLGGPESAVA | ||||||
Modified residue | 21 | In isoform P30427-2; Phosphoserine | ||||
Sequence: R | ||||||
Modified residue | 26 | In isoform P30427-2; Phosphotyrosine | ||||
Sequence: V | ||||||
Modified residue | 723 | Phosphoserine | ||||
Sequence: S | ||||||
Modified residue | 818 | Phosphothreonine | ||||
Sequence: T | ||||||
Modified residue | 1050 | Phosphoserine | ||||
Sequence: S | ||||||
Modified residue | 1438 | Phosphoserine | ||||
Sequence: S | ||||||
Modified residue | 1724 | Phosphoserine | ||||
Sequence: S | ||||||
Modified residue | 1728 | N6-acetyllysine | ||||
Sequence: K | ||||||
Modified residue | 2634 | Phosphoserine | ||||
Sequence: S | ||||||
Modified residue | 2639 | N6-acetyllysine | ||||
Sequence: K | ||||||
Modified residue | 2777 | Phosphoserine | ||||
Sequence: S | ||||||
Modified residue | 2784 | Phosphotyrosine | ||||
Sequence: Y | ||||||
Modified residue | 2805 | Phosphoserine | ||||
Sequence: S | ||||||
Modified residue | 2889 | Phosphothreonine | ||||
Sequence: T | ||||||
Modified residue | 3036 | Phosphotyrosine | ||||
Sequence: Y | ||||||
Modified residue | 3056 | N6-acetyllysine | ||||
Sequence: K | ||||||
Modified residue | 3094 | N6-acetyllysine | ||||
Sequence: K | ||||||
Modified residue | 3365 | Phosphotyrosine | ||||
Sequence: Y | ||||||
Modified residue | 3423 | N6-acetyllysine | ||||
Sequence: K | ||||||
Modified residue | 3583 | Phosphoserine | ||||
Sequence: S | ||||||
Modified residue | 3788 | Phosphothreonine | ||||
Sequence: T | ||||||
Modified residue | 3793 | Phosphotyrosine | ||||
Sequence: Y | ||||||
Modified residue | 4033 | Phosphothreonine | ||||
Sequence: T | ||||||
Modified residue | 4057 | Phosphoserine | ||||
Sequence: S | ||||||
Modified residue | 4385 | Phosphoserine | ||||
Sequence: S | ||||||
Modified residue | 4387 | Phosphoserine | ||||
Sequence: S | ||||||
Modified residue | 4388 | Phosphoserine | ||||
Sequence: S | ||||||
Modified residue | 4389 | Phosphoserine | ||||
Sequence: S | ||||||
Modified residue | 4392 | Phosphoserine | ||||
Sequence: S | ||||||
Modified residue | 4393 | Phosphoserine | ||||
Sequence: S | ||||||
Modified residue | 4394 | Phosphoserine | ||||
Sequence: S | ||||||
Modified residue | 4395 | Phosphoserine | ||||
Sequence: S | ||||||
Modified residue | 4396 | Phosphotyrosine | ||||
Sequence: Y | ||||||
Modified residue | 4399 | Phosphoserine | ||||
Sequence: S | ||||||
Modified residue | 4409 | Phosphoserine | ||||
Sequence: S | ||||||
Modified residue | 4414 | Phosphothreonine | ||||
Sequence: T | ||||||
Modified residue | 4542 | Phosphothreonine; by CDK1 | ||||
Sequence: T | ||||||
Modified residue | 4610 | Phosphoserine | ||||
Sequence: S | ||||||
Modified residue | 4616 | Phosphoserine | ||||
Sequence: S | ||||||
Modified residue | 4618 | Phosphotyrosine | ||||
Sequence: Y | ||||||
Modified residue | 4619 | Phosphoserine | ||||
Sequence: S | ||||||
Modified residue | 4621 | Phosphoserine | ||||
Sequence: S | ||||||
Modified residue | 4625 | Phosphoserine | ||||
Sequence: S | ||||||
Modified residue | 4626 | Phosphothreonine | ||||
Sequence: T | ||||||
Modified residue | 4629 | Phosphoserine | ||||
Sequence: S | ||||||
Modified residue | 4630 | Omega-N-methylarginine | ||||
Sequence: R | ||||||
Modified residue | 4643 | Omega-N-methylarginine | ||||
Sequence: R | ||||||
Modified residue | 4645 | Phosphoserine | ||||
Sequence: S | ||||||
Modified residue | 4678 | Phosphoserine | ||||
Sequence: S |
Post-translational modification
Phosphorylated by CDK1; regulates dissociation from intermediate filaments during mitosis. Isoform 2 is phosphorylated on Ser-21 and Tyr-26 (By similarity).
Keywords
- PTM
Proteomic databases
PTM databases
Expression
Tissue specificity
Widely expressed with highest expression in skeletal muscle and lowest in thymus.
Interaction
Subunit
Homodimer or homotetramer (By similarity).
Interacts (via actin-binding domain) with SYNE3. Interacts (via calponin-homology (CH) 1 domain) with VIM (via rod region). Interacts (via N-terminus) with DST isoform 2 (via N-terminus). Interacts with FER. Interacts with TOR1A (By similarity).
Interacts with ANK3 (PubMed:21223964).
Identified in complexes that contain VIM, EZR, AHNAK, BFSP1, BFSP2, ANK2, PLEC, PRX and spectrin (By similarity).
Interacts (via actin-binding domain) with SYNE3. Interacts (via calponin-homology (CH) 1 domain) with VIM (via rod region). Interacts (via N-terminus) with DST isoform 2 (via N-terminus). Interacts with FER. Interacts with TOR1A (By similarity).
Interacts with ANK3 (PubMed:21223964).
Identified in complexes that contain VIM, EZR, AHNAK, BFSP1, BFSP2, ANK2, PLEC, PRX and spectrin (By similarity).
Protein-protein interaction databases
Family & Domains
Features
Showing features for region, compositional bias, domain, repeat, coiled coil.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 1-1473 | Globular 1 | ||||
Sequence: MVAGMLMPLDQLRAIYEVLFREGVMVAKKDRRPRSLHPHVPGVTNLQVMRAMTSLKARGLVRETFAWCHFYWYLTNEGIDHLRQYLHLPPEIVPASLQRVRRPVAMVMPARRRSPHVQTMQGPLGCPPKRGPLPAEDPAREERQVYRRKEREEGAPETPVVSATIVGTLARPGPEPTPATDERDRVQKKTSTKWVNKHLIKAQRHISDLYEDLRDGHNLISLLEVLSGDSLPREKGRMRFHKLQNVQIALDYLRHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFKISDIQVSGQSEDMTAKEKLLLWSQRMVEGYQGLRCDNFTTSWRDGRLFNAIIHRHKPMLIDMNKVYRQTNLENLDQAFSVAERDLGVTRLLDPEDVDVPQPDEKSIITYVSSLYDAMPRVPGAQDGVRANELQLRWQEYRELVLLLLQWIRHHTAAFEERKFPSSFEEIEILWCQFLKFKETELPAKEADKNRSKGIYQSLEGAVQAGQLKIPPGYHPLDVEKEWGKLHVAILEREKQLRSEFERLECLQRIVSKLQMEAGLCEEQLYQADSLLQSDIRLLASGKAAQRAGEVERDLDKADGMIRLLFNDVQTLKDGRHPQGEQMYRRVYRLHERLVAIRTEYNLRLKAGVGAPVTQVTLQSTQRRPELEDSTLRYLHDLLAWVEENQRRIDGAEWGVDLPSVEAQLGSHRGMHQSIEEFRAKIERARNDESQLSPATRGAYRDCLGRLDLQYAKLLNSSKARLRSLESLHGFVAAATKELMWLNEKEEEEVGFDWSDRNTNMAAKKESYSALMRELEMKEKKIKEIQNTGDRLLREDHPARPTVESFQAALQTQWSWMLQLCCCIEAHLKENTAYFQFFSDVREAEEQLQKLQETLRRKYSCDRSITVTRLEDLLQDAQDEKEQLNEYKGHLSGLAKRAKAIVQLKPRNPAHPVRGHVPLLAVCDYKQVEVTVHKGDQCQLVGPAQPFHWKVLSSSGSEAAVPSVCFLVPPPNQEAQEAVARLEAQHQALVTLWHQLHVDMKSLLAWQSLNRDIQLIRSWSLVTFRTLKPEEQRQALRNLELHYQAFLRDSQDAGGFGPEDRLVAEREYGSCSRHYQQLLQSLEQGEQEESRCQRCISELKDIRLQLEACETRTVHRLRLPLDKDPARECAQRIAEQQKAQAEVEGLGKGVARLSAEAEKVLALPEPSPAAPTLRSELELTLGKLEQVRSLSAIYLEKLKTISLVIRSTQGAEEVLKTHEEHLKEAQAVPATLQELEVTKASLKKLRAQAEAQQPVFNTLRDELRGAQEVGERLQQRHGERDVEVERWRERVTQLLERWQAVLAQTDVRQRELEQLGRQLRYYRESADPLSSWLQDAKSRQEQIQAVPIANSQAAREQLRQEKALLEEIERHGEKVEECQKFAKQYINAIKDYELQLITYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTRYSELTTLTSQY | ||||||
Region | 111-158 | Disordered | ||||
Sequence: RRRSPHVQTMQGPLGCPPKRGPLPAEDPAREERQVYRRKEREEGAPET | ||||||
Compositional bias | 134-156 | Basic and acidic residues | ||||
Sequence: PAEDPAREERQVYRRKEREEGAP | ||||||
Region | 181-406 | Actin-binding | ||||
Sequence: DERDRVQKKTSTKWVNKHLIKAQRHISDLYEDLRDGHNLISLLEVLSGDSLPREKGRMRFHKLQNVQIALDYLRHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFKISDIQVSGQSEDMTAKEKLLLWSQRMVEGYQGLRCDNFTTSWRDGRLFNAIIHRHKPMLIDMNKVYRQTNLENLDQAFSVAERDLGVTRLLDPEDVDVPQPDEKSIITYVSSLYDAMP | ||||||
Domain | 185-288 | Calponin-homology (CH) 1 | ||||
Sequence: RVQKKTSTKWVNKHLIKAQRHISDLYEDLRDGHNLISLLEVLSGDSLPREKGRMRFHKLQNVQIALDYLRHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFK | ||||||
Domain | 301-406 | Calponin-homology (CH) 2 | ||||
Sequence: MTAKEKLLLWSQRMVEGYQGLRCDNFTTSWRDGRLFNAIIHRHKPMLIDMNKVYRQTNLENLDQAFSVAERDLGVTRLLDPEDVDVPQPDEKSIITYVSSLYDAMP | ||||||
Repeat | 648-722 | Spectrin 1 | ||||
Sequence: LQSTQRRPELEDSTLRYLHDLLAWVEENQRRIDGAEWGVDLPSVEAQLGSHRGMHQSIEEFRAKIERARNDESQL | ||||||
Repeat | 743-827 | Spectrin 2 | ||||
Sequence: KLLNSSKARLRSLESLHGFVAAATKELMWLNEKEEEEVGFDWSDRNTNMAAKKESYSALMRELEMKEKKIKEIQNTGDRLLREDH | ||||||
Repeat | 840-933 | Spectrin 3 | ||||
Sequence: LQTQWSWMLQLCCCIEAHLKENTAYFQFFSDVREAEEQLQKLQETLRRKYSCDRSITVTRLEDLLQDAQDEKEQLNEYKGHLSGLAKRAKAIVQ | ||||||
Domain | 944-1001 | SH3 | ||||
Sequence: RGHVPLLAVCDYKQVEVTVHKGDQCQLVGPAQPFHWKVLSSSGSEAAVPSVCFLVPPP | ||||||
Repeat | 1318-1418 | Spectrin 4 | ||||
Sequence: RERVTQLLERWQAVLAQTDVRQRELEQLGRQLRYYRESADPLSSWLQDAKSRQEQIQAVPIANSQAAREQLRQEKALLEEIERHGEKVEECQKFAKQYINA | ||||||
Coiled coil | 1472-1692 | |||||
Sequence: QYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAELEARELQRRMQEEVTRREEAAVDAQQQKRSIQEELQHLRQSSEAEIQAKAQQVEAAERSRMRIEEEIRVVRLQLETTERQRGGAEDELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEAELALRVKAEAEAAREKQRALQALDELKLQAEEAERWL | ||||||
Region | 1474-2758 | Central fibrous rod domain | ||||
Sequence: IKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAELEARELQRRMQEEVTRREEAAVDAQQQKRSIQEELQHLRQSSEAEIQAKAQQVEAAERSRMRIEEEIRVVRLQLETTERQRGGAEDELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEAELALRVKAEAEAAREKQRALQALDELKLQAEEAERWLCQAEAERARQVQVALETAQRSAEVELQSKRPSFAEKTAQLERTLQEEHVTVTQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQADAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLTEGTAQQRLAAEQELIRLRAETEQGEHQRQLLEEELARLQHEATAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEARRHRELAEEDAARQRAEADGVLTEKLAAISEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASESELERQKGLVEDTLRQRRQVEEEIMALKASFEKAAAGKAELELELGRIRSNAEDTMRSKELAEQEAARQRQLAAEEEQRRREAEERVQRSLAAEEEAARQRKVALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFVVQQREEELQQTLQQEQNMLERLRSEAEAARRAAEEAEEAREQAEREAAQSRKQVEEAERLKQSAEEQAQAQAQAQAAAEKLRKEAEQEAARRAQAEQAALKQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKSILDEELQRLKAEVTEAARQRSQVEEELFSVRVQMEELGKLKARIEAENRALILRDKDNTQRFLEEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQADKEQMAQQLVEETQGFQRTLEAERQRQLEMSAEAERLKLRMAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDQDAERLREAIAELEREKEKLKQEAKLLQLKSEEMQTVQQEQILQETQALQKSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAKQLQEEQQRQQQQMEQEKQELVASMEEARRRQREAEEGVRRKQEELQRLEQQRQQQEKLLAEENQRLRERLQRLEEEHRAALAHSEEIATS | ||||||
Region | 1623-1647 | Disordered | ||||
Sequence: EEAEAQKRQAQEEAERLRRQVQDES | ||||||
Coiled coil | 1724-2760 | |||||
Sequence: SFAEKTAQLERTLQEEHVTVTQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQADAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLTEGTAQQRLAAEQELIRLRAETEQGEHQRQLLEEELARLQHEATAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEARRHRELAEEDAARQRAEADGVLTEKLAAISEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASESELERQKGLVEDTLRQRRQVEEEIMALKASFEKAAAGKAELELELGRIRSNAEDTMRSKELAEQEAARQRQLAAEEEQRRREAEERVQRSLAAEEEAARQRKVALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFVVQQREEELQQTLQQEQNMLERLRSEAEAARRAAEEAEEAREQAEREAAQSRKQVEEAERLKQSAEEQAQAQAQAQAAAEKLRKEAEQEAARRAQAEQAALKQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKSILDEELQRLKAEVTEAARQRSQVEEELFSVRVQMEELGKLKARIEAENRALILRDKDNTQRFLEEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQADKEQMAQQLVEETQGFQRTLEAERQRQLEMSAEAERLKLRMAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDQDAERLREAIAELEREKEKLKQEAKLLQLKSEEMQTVQQEQILQETQALQKSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAKQLQEEQQRQQQQMEQEKQELVASMEEARRRQREAEEGVRRKQEELQRLEQQRQQQEKLLAEENQRLRERLQRLEEEHRAALAHSEEIATSQA | ||||||
Region | 1741-1764 | Disordered | ||||
Sequence: VTVTQLREEAERRAQQQAEAERAR | ||||||
Region | 1796-1846 | Disordered | ||||
Sequence: SLAQADAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLTEGTAQ | ||||||
Compositional bias | 1800-1838 | Basic and acidic residues | ||||
Sequence: ADAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQR | ||||||
Region | 2096-2139 | Disordered | ||||
Sequence: EDTMRSKELAEQEAARQRQLAAEEEQRRREAEERVQRSLAAEEE | ||||||
Region | 2164-2188 | Disordered | ||||
Sequence: LRERAEQESARQLQLAQEAAQKRLQ | ||||||
Compositional bias | 2218-2260 | Basic and acidic residues | ||||
Sequence: RLRSEAEAARRAAEEAEEAREQAEREAAQSRKQVEEAERLKQS | ||||||
Region | 2218-2307 | Disordered | ||||
Sequence: RLRSEAEAARRAAEEAEEAREQAEREAAQSRKQVEEAERLKQSAEEQAQAQAQAQAAAEKLRKEAEQEAARRAQAEQAALKQKQAADAEM | ||||||
Compositional bias | 2671-2686 | Polar residues | ||||
Sequence: QEEQQRQQQQMEQEKQ | ||||||
Region | 2671-2710 | Disordered | ||||
Sequence: QEEQQRQQQQMEQEKQELVASMEEARRRQREAEEGVRRKQ | ||||||
Compositional bias | 2687-2710 | Basic and acidic residues | ||||
Sequence: ELVASMEEARRRQREAEEGVRRKQ | ||||||
Region | 2759-4687 | Globular 2 | ||||
Sequence: QAAATKALPNGRDALDGPSMEAEPEYTFEGLRQKVPAQQLQEAGILSMEELQRLTQGHTTVAELTQREDVRHYLKGGSSIAGLLLKPTNEKLSVYTALQRQLLSPGTALILLEAQAASGFLLDPVRNRRLTVNEAVKEGVVGPELHHKLLSAERAVTGYKDPYTGEQISLFQAMKKDLIVRDHGIRLLEAQIATGGIIDPVHSHRVPVDVAYQRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLRLLPLTDKAAKGGELVYTDTEARDVFEKATVSAPFGKFQGKTVTIWEIINSEYFTAEQRRDLLRQFRTGRITVEKIIKIVITVVEEHERKGQLCFEGLRALVPAAELLDSGVISHEVYQQLQRGERSVREVAEADEVRQALRGTSVIAGVWLEEAGQKLSIYEALRRDLLQPEVAVALLEAQAGTGHIIDPATSARLTVDEAVRAGLVGPEMHEKLLSAEKAVTGYRDPYSGQSVSLFQALKKGLIPREQGLRLLDAQLSTGGIVDPSKSHRVPLDVAYARGYLDKETNRALTSPRDDARVYLDPSTREPVTYSQLQQRCRSDQLTGLSLLPLSEKAVRARQEEVYSELQARETLEKAKVEVPVGGFKGRALTVWELISSEYFTEEQRQELLRQFRTGKVTVEKVIKILITIVEEVETQRQERLSFSGLRAPVPASELLASKILSRTQFEQLKDGKTSVKDLSEVGSVRTLLQGSGCLAGIYLEDSKEKVTIYEAMRRGLLRASTATLLLEAQAATGFLVDPVRNQRLYVHEAVKAGVVGPELHEKLLSAEKAVTGYKDPYSGSTISLFQAMKKGLVLRDHAIRLLEAQIATGGIIDPVHSHRLPVDVAYQRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLRLLPLRGAEKTEVVETTQVYTEEETRRAFEETQIDIPGGGSHGGSSMSLWEVMQSDMIPEDQRARLMADFQAGRVTKERMIIIIIEIIEKTEIIRQQNLASYDYVRRRLTAEDLYEARIISLETYNLFREGTKSLREVLEMESAWRYLYGTGSVAGVYLPGSRQTLTIYQALKKGLLSAEVARLLLEAQAATGFLLDPVKGERLTVDEAVRKGLVGPELHDRLLSAERAVTGYRDPYTEQPISLFQAMKKELIPAEEALRLLDAQLATGGIVDPRLGFHLPLEVAYQRGYLNKDTHDQLSEPSEVRSYVDPSTDERLSYTQLLKRCRRDDNSGQMLLPLSDARKLTFRGLRKQITVEELVRSQVMDEATALQLQEGLTSIEEVTKNLQKFLEGTSCIAGVFVDATKERLSVYQAMKKGIIRPGTAFELLEAQAATGYVIDPIKGLKLTVEEAVRMGIVGPEFKDKLLSAERAVTGYKDPYSGKLISLFQAMKKGLILKDHGIRLLEAQIATGGIIDPEESHRLPVEVAYKRGLFDEEMNEILTDPSDDTKGFFDPNTEENLTYLQLMERCITDPQTGLCLLPLKEKKRERKTSSKSSVRKRRVVIVDPETGKEMSVYEAYRKGLIDHQTYLELSEQECEWEEITISSSDGVVKSMIIDRRSGRQYDIGDAITKNLIDRSALDQYRAGTLSITEFADMLSGNAGGFRSRSSSVGSSSSYPISSAVPRTQLASWSDPTEETGPVAGILDTETLEKVSITEAMHRNLVDNITGQRLLEAQACTGGIIDPSTGERFPVTEAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAAQALKKGWLYYEAGQRFLEVQYLTGGLIEPDTPGRVSLDEALQRGTVDARTAQKLRDVSAYSKYLTCPKTKLKISYKDALDRSMVEEGTGLRLLEAAAQSSKGYYSPYSVSGSGSTAGSRTGSRTGSRAGSRRGSFDATGSGFSMTFSSSSYSSSGYGRRYASGPSASLGGPESAVA | ||||||
Repeat | 2791-2828 | Plectin 1 | ||||
Sequence: QKVPAQQLQEAGILSMEELQRLTQGHTTVAELTQREDV | ||||||
Repeat | 2829-2866 | Plectin 2 | ||||
Sequence: RHYLKGGSSIAGLLLKPTNEKLSVYTALQRQLLSPGTA | ||||||
Repeat | 2867-2904 | Plectin 3 | ||||
Sequence: LILLEAQAASGFLLDPVRNRRLTVNEAVKEGVVGPELH | ||||||
Repeat | 2905-2942 | Plectin 4 | ||||
Sequence: HKLLSAERAVTGYKDPYTGEQISLFQAMKKDLIVRDHG | ||||||
Repeat | 2943-2980 | Plectin 5 | ||||
Sequence: IRLLEAQIATGGIIDPVHSHRVPVDVAYQRGYFDEEMN | ||||||
Repeat | 2984-3018 | Plectin 6 | ||||
Sequence: ADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETG | ||||||
Repeat | 3119-3156 | Plectin 7 | ||||
Sequence: ALVPAAELLDSGVISHEVYQQLQRGERSVREVAEADEV | ||||||
Repeat | 3157-3194 | Plectin 8 | ||||
Sequence: RQALRGTSVIAGVWLEEAGQKLSIYEALRRDLLQPEVA | ||||||
Repeat | 3195-3232 | Plectin 9 | ||||
Sequence: VALLEAQAGTGHIIDPATSARLTVDEAVRAGLVGPEMH | ||||||
Repeat | 3233-3270 | Plectin 10 | ||||
Sequence: EKLLSAEKAVTGYRDPYSGQSVSLFQALKKGLIPREQG | ||||||
Repeat | 3271-3308 | Plectin 11 | ||||
Sequence: LRLLDAQLSTGGIVDPSKSHRVPLDVAYARGYLDKETN | ||||||
Repeat | 3311-3346 | Plectin 12 | ||||
Sequence: LTSPRDDARVYLDPSTREPVTYSQLQQRCRSDQLTG | ||||||
Repeat | 3488-3525 | Plectin 13 | ||||
Sequence: RTLLQGSGCLAGIYLEDSKEKVTIYEAMRRGLLRASTA | ||||||
Repeat | 3526-3563 | Plectin 14 | ||||
Sequence: TLLLEAQAATGFLVDPVRNQRLYVHEAVKAGVVGPELH | ||||||
Repeat | 3564-3601 | Plectin 15 | ||||
Sequence: EKLLSAEKAVTGYKDPYSGSTISLFQAMKKGLVLRDHA | ||||||
Repeat | 3602-3639 | Plectin 16 | ||||
Sequence: IRLLEAQIATGGIIDPVHSHRLPVDVAYQRGYFDEEMN | ||||||
Repeat | 3643-3677 | Plectin 17 | ||||
Sequence: ADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETG | ||||||
Repeat | 3823-3860 | Plectin 18 | ||||
Sequence: WRYLYGTGSVAGVYLPGSRQTLTIYQALKKGLLSAEVA | ||||||
Repeat | 3861-3898 | Plectin 19 | ||||
Sequence: RLLLEAQAATGFLLDPVKGERLTVDEAVRKGLVGPELH | ||||||
Repeat | 3899-3936 | Plectin 20 | ||||
Sequence: DRLLSAERAVTGYRDPYTEQPISLFQAMKKELIPAEEA | ||||||
Repeat | 3937-3974 | Plectin 21 | ||||
Sequence: LRLLDAQLATGGIVDPRLGFHLPLEVAYQRGYLNKDTH | ||||||
Repeat | 3978-4011 | Plectin 22 | ||||
Sequence: SEPSEVRSYVDPSTDERLSYTQLLKRCRRDDNSG | ||||||
Repeat | 4066-4103 | Plectin 23 | ||||
Sequence: QKFLEGTSCIAGVFVDATKERLSVYQAMKKGIIRPGTA | ||||||
Repeat | 4104-4141 | Plectin 24 | ||||
Sequence: FELLEAQAATGYVIDPIKGLKLTVEEAVRMGIVGPEFK | ||||||
Repeat | 4142-4179 | Plectin 25 | ||||
Sequence: DKLLSAERAVTGYKDPYSGKLISLFQAMKKGLILKDHG | ||||||
Repeat | 4180-4217 | Plectin 26 | ||||
Sequence: IRLLEAQIATGGIIDPEESHRLPVEVAYKRGLFDEEMN | ||||||
Repeat | 4221-4255 | Plectin 27 | ||||
Sequence: TDPSDDTKGFFDPNTEENLTYLQLMERCITDPQTG | ||||||
Region | 4253-4303 | Binding to intermediate filaments | ||||
Sequence: QTGLCLLPLKEKKRERKTSSKSSVRKRRVVIVDPETGKEMSVYEAYRKGLI | ||||||
Repeat | 4268-4308 | Plectin 28 | ||||
Sequence: RKTSSKSSVRKRRVVIVDPETGKEMSVYEAYRKGLIDHQTY | ||||||
Repeat | 4411-4448 | Plectin 29 | ||||
Sequence: SDPTEETGPVAGILDTETLEKVSITEAMHRNLVDNITG | ||||||
Repeat | 4449-4486 | Plectin 30 | ||||
Sequence: QRLLEAQACTGGIIDPSTGERFPVTEAVNKGLVDKIMV | ||||||
Repeat | 4487-4524 | Plectin 31 | ||||
Sequence: DRINLAQKAFCGFEDPRTKTKMSAAQALKKGWLYYEAG | ||||||
Repeat | 4525-4562 | Plectin 32 | ||||
Sequence: QRFLEVQYLTGGLIEPDTPGRVSLDEALQRGTVDARTA | ||||||
Repeat | 4563-4600 | Plectin 33 | ||||
Sequence: QKLRDVSAYSKYLTCPKTKLKISYKDALDRSMVEEGTG | ||||||
Compositional bias | 4614-4671 | Polar residues | ||||
Sequence: YYSPYSVSGSGSTAGSRTGSRTGSRAGSRRGSFDATGSGFSMTFSSSSYSSSGYGRRY | ||||||
Region | 4614-4687 | Disordered | ||||
Sequence: YYSPYSVSGSGSTAGSRTGSRTGSRAGSRRGSFDATGSGFSMTFSSSSYSSSGYGRRYASGPSASLGGPESAVA | ||||||
Region | 4628-4643 | 4 X 4 AA tandem repeats of G-S-R-X | ||||
Sequence: GSRTGSRTGSRAGSRR |
Domain
The N-terminus interacts with actin, the C-terminus with vimentin, desmin, GFAP, cytokeratins, lamin B; whereas both the N- and the C-terminus can bind integrin beta-4.
Sequence similarities
Belongs to the plakin or cytolinker family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence & Isoforms
- Sequence statusComplete
This entry describes 4 isoforms produced by Alternative splicing.
P30427-1
This isoform has been chosen as the canonical sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
- Name1
- Length4,687
- Mass (Da)533,540
- Last updated1996-10-01 v2
- Checksum9966CAF71B929751
P30427-2
- Name2
- Differences from canonical
- 1-180: MVAGMLMPLDQLRAIYEVLFREGVMVAKKDRRPRSLHPHVPGVTNLQVMRAMTSLKARGLVRETFAWCHFYWYLTNEGIDHLRQYLHLPPEIVPASLQRVRRPVAMVMPARRRSPHVQTMQGPLGCPPKRGPLPAEDPAREERQVYRRKEREEGAPETPVVSATIVGTLARPGPEPTPAT → MSQQRLRVPEPEGLGSKRTSSEDNLYLAVLRASEGKK
P30427-3
- Name3
- Differences from canonical
- 1-180: MVAGMLMPLDQLRAIYEVLFREGVMVAKKDRRPRSLHPHVPGVTNLQVMRAMTSLKARGLVRETFAWCHFYWYLTNEGIDHLRQYLHLPPEIVPASLQRVRRPVAMVMPARRRSPHVQTMQGPLGCPPKRGPLPAEDPAREERQVYRRKEREEGAPETPVVSATIVGTLARPGPEPTPAT → MEPSGSLFPSLVVVGHVVSLAAVWHWRKGHRQAQDEQ
P30427-4
- Name4
- NoteIncomplete sequence.
- Differences from canonical
- 1-180: MVAGMLMPLDQLRAIYEVLFREGVMVAKKDRRPRSLHPHVPGVTNLQVMRAMTSLKARGLVRETFAWCHFYWYLTNEGIDHLRQYLHLPPEIVPASLQRVRRPVAMVMPARRRSPHVQTMQGPLGCPPKRGPLPAEDPAREERQVYRRKEREEGAPETPVVSATIVGTLARPGPEPTPAT → DVSNGSSGSPSPGDTLPWNLGKTQRSRRSGGGSVGNGSVLDPAERAVIRIA
Computationally mapped potential isoform sequences
There are 4 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A0G2K5T2 | A0A0G2K5T2_RAT | Plec | 4692 | ||
A0A0G2JYZ5 | A0A0G2JYZ5_RAT | Plec | 4517 | ||
A0A0G2JY63 | A0A0G2JY63_RAT | Plec | 4540 | ||
F7F9U6 | F7F9U6_RAT | Plec | 4549 |
Features
Showing features for alternative sequence, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Alternative sequence | VSP_005050 | 1-180 | in isoform 2 | |||
Sequence: MVAGMLMPLDQLRAIYEVLFREGVMVAKKDRRPRSLHPHVPGVTNLQVMRAMTSLKARGLVRETFAWCHFYWYLTNEGIDHLRQYLHLPPEIVPASLQRVRRPVAMVMPARRRSPHVQTMQGPLGCPPKRGPLPAEDPAREERQVYRRKEREEGAPETPVVSATIVGTLARPGPEPTPAT → MSQQRLRVPEPEGLGSKRTSSEDNLYLAVLRASEGKK | ||||||
Alternative sequence | VSP_005051 | 1-180 | in isoform 3 | |||
Sequence: MVAGMLMPLDQLRAIYEVLFREGVMVAKKDRRPRSLHPHVPGVTNLQVMRAMTSLKARGLVRETFAWCHFYWYLTNEGIDHLRQYLHLPPEIVPASLQRVRRPVAMVMPARRRSPHVQTMQGPLGCPPKRGPLPAEDPAREERQVYRRKEREEGAPETPVVSATIVGTLARPGPEPTPAT → MEPSGSLFPSLVVVGHVVSLAAVWHWRKGHRQAQDEQ | ||||||
Alternative sequence | VSP_005052 | 1-180 | in isoform 4 | |||
Sequence: MVAGMLMPLDQLRAIYEVLFREGVMVAKKDRRPRSLHPHVPGVTNLQVMRAMTSLKARGLVRETFAWCHFYWYLTNEGIDHLRQYLHLPPEIVPASLQRVRRPVAMVMPARRRSPHVQTMQGPLGCPPKRGPLPAEDPAREERQVYRRKEREEGAPETPVVSATIVGTLARPGPEPTPAT → DVSNGSSGSPSPGDTLPWNLGKTQRSRRSGGGSVGNGSVLDPAERAVIRIA | ||||||
Compositional bias | 134-156 | Basic and acidic residues | ||||
Sequence: PAEDPAREERQVYRRKEREEGAP | ||||||
Compositional bias | 1800-1838 | Basic and acidic residues | ||||
Sequence: ADAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQR | ||||||
Compositional bias | 2218-2260 | Basic and acidic residues | ||||
Sequence: RLRSEAEAARRAAEEAEEAREQAEREAAQSRKQVEEAERLKQS | ||||||
Compositional bias | 2671-2686 | Polar residues | ||||
Sequence: QEEQQRQQQQMEQEKQ | ||||||
Compositional bias | 2687-2710 | Basic and acidic residues | ||||
Sequence: ELVASMEEARRRQREAEEGVRRKQ | ||||||
Compositional bias | 4614-4671 | Polar residues | ||||
Sequence: YYSPYSVSGSGSTAGSRTGSRTGSRAGSRRGSFDATGSGFSMTFSSSSYSSSGYGRRY |
Keywords
- Coding sequence diversity
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
X59601 EMBL· GenBank· DDBJ | CAA42169.1 EMBL· GenBank· DDBJ | mRNA | ||
U96274 EMBL· GenBank· DDBJ | AAC53209.1 EMBL· GenBank· DDBJ | mRNA | ||
U96275 EMBL· GenBank· DDBJ | AAC53210.1 EMBL· GenBank· DDBJ | mRNA | ||
U96276 EMBL· GenBank· DDBJ | AAC53211.1 EMBL· GenBank· DDBJ | mRNA |