P29619 · CDKA2_ORYSJ

Function

Catalytic activity

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site10-18ATP (UniProtKB | ChEBI)
Binding site33ATP (UniProtKB | ChEBI)
Active site126Proton acceptor

GO annotations

AspectTerm
Cellular Componentcyclin-dependent protein kinase holoenzyme complex
Cellular Componentcytoplasm
Cellular Componentnucleus
Cellular ComponentNuRD complex
Molecular FunctionATP binding
Molecular Functioncyclin binding
Molecular Functioncyclin-dependent protein serine/threonine kinase activity
Molecular Functionprotein serine kinase activity
Molecular FunctionRNA polymerase II CTD heptapeptide repeat kinase activity
Biological ProcessG1/S transition of mitotic cell cycle
Biological Processregulation of G2/M transition of mitotic cell cycle
Biological Processregulation of gene expression
Biological Processregulation of meiotic cell cycle
Biological Processsignal transduction

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Cyclin-dependent kinase A-2
  • EC number
  • Short names
    CDKA;2
  • Alternative names
    • CDC2Os-2
    • Cell division control protein 2 homolog 2

Gene names

    • Name
      CDKA-2
    • Synonyms
      CDC2-2
    • ORF names
      P0575F10.10-1, P0575F10.10-2
    • Ordered locus names
      Os02g0123100, LOC_Os02g03060

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Nipponbare
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > Liliopsida > Poales > Poaceae > BOP clade > Oryzoideae > Oryzeae > Oryzinae > Oryza > Oryza sativa

Accessions

  • Primary accession
    P29619
  • Secondary accessions
    • B7ERM3
    • Q0E4E3
    • Q6Z721
    • Q6Z722

Proteomes

Genome annotation databases

PTM/Processing

Features

Showing features for chain, modified residue, modified residue (large scale data).

TypeIDPosition(s)SourceDescription
ChainPRO_00000857561-292UniProtCyclin-dependent kinase A-2
Modified residue14UniProtPhosphothreonine
Modified residue15UniProtPhosphotyrosine
Modified residue (large scale data)158PTMeXchangePhosphothreonine
Modified residue160UniProtPhosphothreonine
Modified residue (large scale data)160PTMeXchangePhosphothreonine

Keywords

Proteomic databases

Expression

Tissue specificity

Expressed in the dividing region of the root apex and in differentiated cells such as those in the sclerenchyma, pericycle and parenchyma of the central cylinder. Expressed in the intercalary meristem and the elongation zone of internodes.

Induction

By gibberellic acid (GA3) and submergence. Down-regulated by auxin.

Developmental stage

Expression reaches a peak in the G1/S phases and then decreases in the G2/M phases.

Gene expression databases

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain4-286Protein kinase

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    292
  • Mass (Da)
    33,693
  • Last updated
    1993-04-01 v1
  • Checksum
    C7791576349DFE22
MEQYEKVEKIGEGTYGVVYKGKHRHTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQHRNIVRLQDVVHKEKCIYLVFEYLDLDLKKHMDSSPDFKNHRIVKSFLYQILRGIAYCHSHRVLHRDLKPQNLLIDRRTNSLKLADFGLARAFGIPVRTFTHEVVTLWYRAPEILLGARHYSTPVDMWSVGCIFAEMVNQKPLFPGDSEIDELFKIFSIMGTPNEETWPGVASLPDYISTFPKWPSVDLATVVPTLDSSGLDLLSKMLRLDPSKRINARAALEHEYFKDLEVA

Computationally mapped potential isoform sequences

There are 2 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
B7E9N8B7E9N8_ORYSJOs02g0123100376
A0A0N7KEL2A0A0N7KEL2_ORYSJOs02g0123100144

Sequence caution

The sequence BAD07950.1 differs from that shown. Reason: Erroneous gene model prediction

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
X60375
EMBL· GenBank· DDBJ
CAA42923.1
EMBL· GenBank· DDBJ
mRNA
AP004885
EMBL· GenBank· DDBJ
BAD07949.1
EMBL· GenBank· DDBJ
Genomic DNA
AP004885
EMBL· GenBank· DDBJ
BAD07950.1
EMBL· GenBank· DDBJ
Genomic DNA Sequence problems.
AP008208
EMBL· GenBank· DDBJ
BAF07645.1
EMBL· GenBank· DDBJ
Genomic DNA
AP014958
EMBL· GenBank· DDBJ
BAS76730.1
EMBL· GenBank· DDBJ
Genomic DNA
AK101344
EMBL· GenBank· DDBJ
BAG95020.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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