P29515 · TBB7_ARATH

Function

function

Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

Miscellaneous

There are nine genes coding for beta-tubulin.

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Features

Showing features for binding site.

144950100150200250300350400
TypeIDPosition(s)Description
Binding site11GTP (UniProtKB | ChEBI)
Binding site69GTP (UniProtKB | ChEBI)
Binding site69Mg2+ (UniProtKB | ChEBI)
Binding site138GTP (UniProtKB | ChEBI)
Binding site142GTP (UniProtKB | ChEBI)
Binding site143GTP (UniProtKB | ChEBI)
Binding site144GTP (UniProtKB | ChEBI)
Binding site204GTP (UniProtKB | ChEBI)
Binding site226GTP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Cellular ComponentGolgi apparatus
Cellular Componentmicrotubule
Cellular Componentperoxisome
Cellular Componentplant-type cell wall
Cellular Componentplasma membrane
Cellular Componentplasmodesma
Cellular Componenttubulin complex
Cellular Componentvacuole
Molecular FunctionGTP binding
Molecular FunctionGTPase activity
Molecular Functionmetal ion binding
Molecular FunctionmRNA binding
Molecular Functionstructural constituent of cytoskeleton
Biological Processmicrotubule-based process

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Tubulin beta-7 chain
  • Alternative names
    • Beta-7-tubulin

Gene names

    • Name
      TUBB7
    • Synonyms
      TUB7
    • ORF names
      F16P2.7
    • Ordered locus names
      At2g29550

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Columbia
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis

Accessions

  • Primary accession
    P29515

Proteomes

Organism-specific databases

Genome annotation databases

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00000483261-449Tubulin beta-7 chain

Proteomic databases

PTM databases

Expression

Gene expression databases

Interaction

Subunit

Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for region, compositional bias.

TypeIDPosition(s)Description
Region422-449Disordered
Compositional bias428-449Acidic residues

Sequence similarities

Belongs to the tubulin family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    449
  • Mass (Da)
    50,747
  • Last updated
    1993-04-01 v1
  • Checksum
    CB61368BF21A77B0
MREILHIQGGQCGNQIGSKFWEVVNLEHGIDQTGRYVGDSELQLERVNVYYNEASCGRYVPRAVLMDLEPGTMDSVRSGPYGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELIDSVLDVVRKEAENCDCLQGFQVCHSLGGGTGSGMGTLLISKIREEYPDRMMMTFSVFPSPKVSDTVVEPYNATLSVHQLVENADECMVLDNEALYDICFRTLKLSTPSFGDLNHLISATMSGVTCCLRFPGQLNSDLRKLAVNLIPFPRLHFFMVGFAPLTSRGSQQYRNLTVPELTQQMWDAKNMMCAADPRHGRYLTASAMFRGKMSTKEVDEQMLNVQNKNSSYFVEWIPNNVKSTVCDIPPTGLKMASTFIGNSTSIQEMFRRVSEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATADEEGEYEEEEAEYEQEETY

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias428-449Acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
M84704
EMBL· GenBank· DDBJ
AAA32885.1
EMBL· GenBank· DDBJ
Genomic DNA
AC004561
EMBL· GenBank· DDBJ
AAC95184.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002685
EMBL· GenBank· DDBJ
AEC08272.1
EMBL· GenBank· DDBJ
Genomic DNA
AF370568
EMBL· GenBank· DDBJ
AAK49574.1
EMBL· GenBank· DDBJ
mRNA
AY090345
EMBL· GenBank· DDBJ
AAL91251.1
EMBL· GenBank· DDBJ
mRNA
BT001121
EMBL· GenBank· DDBJ
AAN64512.1
EMBL· GenBank· DDBJ
mRNA
AY085710
EMBL· GenBank· DDBJ
AAM62928.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

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