P28270 · DHE3_ELEEL

Function

function

Mitochondrial glutamate dehydrogenase that converts L-glutamate into alpha-ketoglutarate. Plays a key role in glutamine anaplerosis by producing alpha-ketoglutarate, an important intermediate in the tricarboxylic acid cycle (By similarity).

Catalytic activity

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site31substrate

GO annotations

AspectTerm
Cellular Componentmitochondrial matrix
Molecular Functionglutamate dehydrogenase (NAD+) activity
Molecular Functionglutamate dehydrogenase (NADP+) activity
Molecular Functionglutamate dehydrogenase [NAD(P)+] activity
Biological Processglutamine metabolic process
Biological Processtricarboxylic acid metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Glutamate dehydrogenase
  • EC number
  • Short names
    GDH

Organism names

Accessions

  • Primary accession
    P28270

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00001827441-51Glutamate dehydrogenase

Interaction

Subunit

Homohexamer.

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Family and domain databases

Sequence

  • Sequence status
    Fragments
  • Length
    51
  • Mass (Da)
    5,650
  • Last updated
    1992-12-01 v1
  • Checksum
    499A36DF9A05B004
SEAVAEKEDDPNFFKMVEGFFDKGAAIVENKLVEDLKTRGSPEVEGNLTFT

Features

Showing features for non-adjacent residues, non-terminal residue.

TypeIDPosition(s)Description
Non-adjacent residues43-44
Non-terminal residue51

Keywords

Similar Proteins

Disclaimer

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