Charcot-Marie-Tooth disease-related PMP22 is trapped in the endoplasmic reticulum by calnexin-dependent retention and Rer1-mediated early Golgi retrieval systems and partly degraded by the Hrd1-mediated endoplasmic reticulum-associated degradation system.
These findings demonstrated that calnexin strictly monitors the maturation of S protein by its direct binding resulting in conferring infectivity on severe acute respiratory syndrome coronavirus., Pathway
Categories
Function, Interaction, Subcellular Location, Function
the phosphorylation state of the calnexin cytosolic domain and its interaction with PACS-2 sort the chaperone between domains of the ER and the plasma membrane, Phosphorylation
proportion of the human and the rat WT gonadotropin-releasing hormone receptor appears to be retained in the endoplasmic reticulum by calnexin an effect that decreases GnRHR signaling capacity
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