The nucleotide sequence of a mouse cDNA encoding the 80 kDa subunit of the Ku (p70/p80) autoantigen.Falzon M., Kuff E.L.Cited forNUCLEOTIDE SEQUENCE [MRNA]StrainBALB/cJCategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCNucleic Acids Res. 20:3784-3784 (1992)Cited in1Mapped to7
Ku gene mutation of radiosensitive mouse mammary carcinoma cell line SX-9.Jiang G.C., Yuan L.Z., Wei K.Cited forNUCLEOTIDE SEQUENCE [MRNA]TissueMammary carcinomaCategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)Submission Submitted to EMBL/GenBank/DDBJ databases (JUL-1999)Cited in1
The transcriptional landscape of the mammalian genome.Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B.[...], Hayashizaki Y.View abstractCited forNUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]StrainC57BL/6J, NODTissueEmbryonic head, Embryonic heart, Embryonic liver, Kidney, ThymusCategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCScience 309:1559-1563 (2005)Cited in99+16Mapped to99+
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).The MGC Project TeamView abstractCited forNUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]Strain129/Sv X 129SvCp, FVB/NTissueEmbryonic stem cell, Mammary tumorCategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCGenome Res. 14:2121-2127 (2004)Cited in99+99+
Non-histone protein 1 (NHP1) is a member of the Ku protein family which is upregulated in differentiating mouse myoblasts and human promyelocytes.Oderwald H., Hughes M.J., Jost J.-P.View abstractCited forDEVELOPMENTAL STAGE, INDUCTIONCategoriesExpressionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCFEBS Lett. 382:313-318 (1996)Cited in4
A tissue-specific atlas of mouse protein phosphorylation and expression.Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R., Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.View abstractCited forIDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]TissueKidney, Liver, Lung, Pancreas, Spleen, TestisCategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCCell 143:1174-1189 (2010)Cited in99+99+Mapped to6
MRI is a DNA damage response adaptor during classical non-homologous end joining.Hung P.J., Johnson B., Chen B.R., Byrum A.K., Bredemeyer A.L., Yewdell W.T., Johnson T.E., Lee B.J., Deivasigamani S.[...], Sleckman B.P.View abstractCited forINTERACTION WITH CYRENCategoriesInteractionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCMol. Cell 71:332-342 (2018)Cited in9Mapped to24
Catalytic subunit of DNA-dependent protein kinase: impact on lymphocyte development and tumorigenesis.Kurimasa A., Ouyang H., Dong L.J., Wang S., Li X., Cordon-Cardo C., Chen D.J., Li G.C.View abstractCategoriesFunctionSourceMGI: 104517PubMedEurope PMCProc Natl Acad Sci U S A 96:1403-1408 (1999)Mapped to9
Targeted disruption of the gene encoding DNA ligase IV leads to lethality in embryonic mice.Barnes D.E., Stamp G., Rosewell I., Denzel A., Lindahl T.View abstractCategoriesFunctionSourceMGI: 104517PubMedEurope PMCCurr. Biol. 8:1395-1398 (1998)Cited in1Mapped to8
Ku80 is required for immunoglobulin isotype switching.Casellas R., Nussenzweig A., Wuerffel R., Pelanda R., Reichlin A., Suh H., Qin X.F., Besmer E., Kenter A.[...], Nussenzweig M.C.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 104517PubMedEurope PMCEMBO J 17:2404-2411 (1998)Mapped to7
Hypersensitivity of Ku80-deficient cell lines and mice to DNA damage: the effects of ionizing radiation on growth, survival, and development.Nussenzweig A., Sokol K., Burgman P., Li L., Li G.C.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 104517PubMedEurope PMCProc Natl Acad Sci U S A 94:13588-13593 (1997)Mapped to2
Double-strand break repair by Ku70 requires heterodimerization with Ku80 and DNA binding functions.Jin S., Weaver D.T.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 104517PubMedEurope PMCEMBO J. 16:6874-6885 (1997)Cited in2Mapped to8
Ku70 is required for DNA repair but not for T cell antigen receptor gene recombination In vivo.Ouyang H., Nussenzweig A., Kurimasa A., Soares V.C., Li X., Cordon-Cardo C., Li W.h., Cheong N., Nussenzweig M.[...], Li G.C.View abstractCategoriesFunctionSourceMGI: 104517PubMedEurope PMCJ Exp Med 186:921-929 (1997)Mapped to8
V(D)J recombination in Ku86-deficient mice: distinct effects on coding, signal, and hybrid joint formation.Bogue M.A., Wang C., Zhu C., Roth D.B.View abstractCategoriesSequencesSourceMGI: 104517PubMedEurope PMCImmunity 7:37-47 (1997)Mapped to2
Chromosomal localization of the mouse and rat DNA double-strand break repair genes Ku p70 and Ku p80/XRCC5 and their mRNA expression in various mouse tissues.Koike M., Matsuda Y., Mimori T., Harada Y.N., Shiomi N., Shiomi T.View abstractCategoriesSequencesSourceMGI: 104517PubMedEurope PMCGenomics 38:38-44 (1996)Mapped to21
A mutation in mouse rad51 results in an early embryonic lethal that is suppressed by a mutation in p53.Lim D.S., Hasty P.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 104517PubMedEurope PMCMol Cell Biol 16:7133-7143 (1996)Mapped to20
Ku86-deficient mice exhibit severe combined immunodeficiency and defective processing of V(D)J recombination intermediates.Zhu C., Bogue M.A., Lim D.S., Hasty P., Roth D.B.View abstractCategoriesFunctionSourceMGI: 104517PubMedEurope PMCCell 86:379-389 (1996)Mapped to2
Requirement for Ku80 in growth and immunoglobulin V(D)J recombination.Nussenzweig A., Chen C., da Costa Soares V., Sanchez M., Sokol K., Nussenzweig M.C., Li G.C.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 104517PubMedEurope PMCNature 382:551-555 (1996)Mapped to2
Restoration of X-ray and etoposide resistance, Ku-end binding activity and V(D) J recombination to the Chinese hamster sxi-3 mutant by a hamster Ku86 cDNA.He D.M., Lee S.E., Hendrickson E.A.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 104517PubMedEurope PMCMutat Res 363:43-56 (1996)Cited in1Mapped to2
<i>Xrcc5/</i>KU80 is not required for the survival or activation of prophase-arrested oocytes in primordial follicles.Ratnayaka-Gamage N.D., Alesi L.R., Zerafa N., Stringer J.M., Hutt K.J.View abstractAnnotationXrcc5/KU80 is not required for the survival or activation of prophase-arrested oocytes in primordial follicles.SourceGeneRif: 22596, MGI: 104517PubMedEurope PMCFront Endocrinol (Lausanne) 14:1268009-1268009 (2023)Mapped to2
Xrcc5/Ku80 is required for the repair of DNA damage in fully grown meiotically arrested mammalian oocytes.Cai X., Stringer J.M., Zerafa N., Carroll J., Hutt K.J.View abstractAnnotationXrcc5/Ku80 is required for the repair of DNA damage in fully grown meiotically arrested mammalian oocytes.CategoriesFunctionSourceGeneRif: 22596, MGI: 104517PubMedEurope PMCCell Death Dis 14:397-397 (2023)Mapped to2
A transposase-derived gene required for human brain development.Zapater L.J., Rodriguez-Fos E., Planas-Felix M., Lewis S., Cameron D., Demarest P., Nabila A., Zhao J., Bergin P.[...], Kentsis A.View abstractSourceMGI: 104517PubMedEurope PMCbioRxiv 0:2023.04.28.538770-2023.04.28.538770 (2023)Mapped to6
DCLK1 promotes colorectal cancer stemness and aggressiveness via the XRCC5/COX2 axis.Kim J.H., Park S.Y., Jeon S.E., Choi J.H., Lee C.J., Jang T.Y., Yun H.J., Lee Y., Kim P.[...], Nam J.S.View abstractAnnotationDCLK1 promotes colorectal cancer stemness and aggressiveness via the XRCC5/COX2 axis.CategoriesFunctionSourceGeneRif: 22596PubMedEurope PMCTheranostics 12:5258-5271 (2022)Mapped to34
Characterization of Double-Strand Break Repair Protein Ku80 Location Within the Murine Retina.Muller B., Serafin F., Laucke L.L., Rheinhard W., Wimmer T., Stieger K.View abstractAnnotationCharacterization of Double-Strand Break Repair Protein Ku80 Location Within the Murine Retina.CategoriesExpressionSourceGeneRif: 22596, MGI: 104517PubMedEurope PMCInvest Ophthalmol Vis Sci 63:22-22 (2022)Mapped to11
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.Bedogni F., Hevner R.F.View abstractSourceMGI: 104517PubMedEurope PMCFront Mol Neurosci 14:686034-686034 (2021)Mapped to99+