P27574 · PYP1_SCHPO

Function

function

Plays a role in inhibiting the onset of mitosis. Dephosphorylates sty1/spc1 and wis1/spc2/sty2.

Catalytic activity

Features

Showing features for active site.

155050100150200250300350400450500550
TypeIDPosition(s)Description
Active site470Phosphocysteine intermediate

GO annotations

AspectTerm
Cellular Componentcytoplasm
Cellular Componentcytosol
Cellular Componentnucleus
Cellular Componentprotein aggregate center
Molecular FunctionMAP kinase tyrosine phosphatase activity
Molecular Functionprotein tyrosine phosphatase activity
Biological Processcell division
Biological Processnegative regulation of p38MAPK cascade
Biological Processprotein dephosphorylation
Biological Processregulation of p38MAPK cascade

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Tyrosine-protein phosphatase 1
  • EC number
  • Alternative names
    • Protein-tyrosine phosphatase 1 (PTPase 1)

Gene names

    • Name
      pyp1
    • ORF names
      SPAC26F1.10c

Organism names

Accessions

  • Primary accession
    P27574

Proteomes

Organism-specific databases

Subcellular Location

PTM/Processing

Features

Showing features for chain, modified residue.

Type
IDPosition(s)Description
ChainPRO_00000948581-550Tyrosine-protein phosphatase 1
Modified residue318Phosphoserine
Modified residue320Phosphoserine

Keywords

Proteomic databases

PTM databases

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain260-539Tyrosine-protein phosphatase

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    550
  • Mass (Da)
    61,588
  • Last updated
    1992-08-01 v1
  • MD5 Checksum
    509EB167E4379DEBE193F8D2B4E3F9C3
MNFSNGSKSSTFTIAPSGSCIALPPQRGVATSKYAVHASCLQEYLDKEAWKDDTLIIDLRPVSEFSKSRIKGSVNLSLPATLIKRPAFSVARIISNLHDVDDKRDFQNWQEFSSILVCVPAWIANYVTNAEVIGEKFRKESYSGDFGILDLDYSKVSGKYPSVIDNSPVKSKLGALPSARPRLSYSAAQTAPISLSSEGSDYFSRPPPTPNVAGLSLNNFFCPLPENKDNKSSPFGSATVQTPCLHSVPDAFTNPDVATLYQKFLRLQSLEHQRLVSCSDRNSQWSTVDSLSNTSYKKNRYTDIVPYNCTRVHLKRTSPSELDYINASFIKTETSNYIACQGSISRSISDFWHMVWDNVENIGTIVMLGSLFEAGREMCTAYWPSNGIGDKQVYGDYCVKQISEENVDNSRFILRKFEIQNANFPSVKKVHHYQYPNWSDCNSPENVKSMVEFLKYVNNSHGSGNTIVHCSAGVGRTGTFIVLDTILRFPESKLSGFNPSVADSSDVVFQLVDHIRKQRMKMVQTFTQFKYVYDLIDSLQKSQVHFPVLT

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
M63257
EMBL· GenBank· DDBJ
AAA35328.1
EMBL· GenBank· DDBJ
mRNA
CU329670
EMBL· GenBank· DDBJ
CAA97367.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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