P26664 · POLG_HCV1
- ProteinGenome polyprotein
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids3011 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score5/5
Publications for P26664
Crystal structure of the hepatitis C virus NS3 protease domain complexed with a synthetic NS4A cofactor peptide.
- CategoriesStructure
Cited inMapped toMulti-input chemical control of protein dimerization for programming graded cellular responses.
- CategoriesStructure
- SourcePDB: 6N4N
Aminoacylase 3 binds to and cleaves the N-terminus of the hepatitis C virus core protein.
- CategoriesInteraction
- SourceIntAct: P26664
The molecular basis of drug resistance against hepatitis C virus NS3/4A protease inhibitors.
- CategoriesStructure
- SourcePDB: 3SU4
1a/1b subtype profiling of nonnucleoside polymerase inhibitors of hepatitis C virus.
- CategoriesStructure
- SourcePDB: 3HKW
P4 capped amides and lactams as HCV NS3 protease inhibitors with improved potency and DMPK profile.
- CategoriesStructure
- SourcePDB: 3KN2
Potent inhibitors of HCV-NS3 protease derived from boronic acids.
- CategoriesStructure
- SourcePDB: 3EYD
Hepatitis C virus RNA replication is regulated by FKBP8 and Hsp90.
- CategoriesInteraction
- SourceIntAct: P26664
Hepatitis C virus core protein blocks interferon signaling by interaction with the STAT1 SH2 domain.
- CategoriesInteraction
- SourceIntAct: P26664
P2-P4 macrocyclic inhibitors of hepatitis C virus NS3-4A serine protease.
- CategoriesStructure
- SourcePDB: 2GVF
Hepatitis C NS3 protease inhibition by peptidyl-alpha-ketoamide inhibitors: kinetic mechanism and structure.
- CategoriesStructure
- SourcePDB: 2GVF
Inhibition of the hepatitis C virus NS3/4A protease. The crystal structures of two protease-inhibitor complexes.
- CategoriesStructure
- SourcePDB: 2A4G