P26567 · CLPP_MAIZE

  • Protein
    ATP-dependent Clp protease proteolytic subunit
  • Gene
    clpP
  • Status
    UniProtKB reviewed (Swiss-Prot)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.

Catalytic activity

  • Hydrolysis of proteins to small peptides in the presence of ATP and magnesium. alpha-casein is the usual test substrate. In the absence of ATP, only oligopeptides shorter than five residues are hydrolyzed (such as succinyl-Leu-Tyr-|-NHMec, and Leu-Tyr-Leu-|-Tyr-Trp, in which cleavage of the -Tyr-|-Leu- and -Tyr-|-Trp bonds also occurs).
    EC:3.4.21.92 (UniProtKB | ENZYME | Rhea)

Features

Showing features for active site.

121620406080100120140160180200
TypeIDPosition(s)Description
Active site101Nucleophile
Active site126

GO annotations

AspectTerm
Cellular Componentchloroplast stroma
Cellular Componentendopeptidase Clp complex
Molecular FunctionATP-dependent peptidase activity
Molecular FunctionATPase binding
Molecular Functionserine-type endopeptidase activity
Biological Processprotein quality control for misfolded or incompletely synthesized proteins

Keywords

Enzyme and pathway databases

Protein family/group databases

Names & Taxonomy

Protein names

  • Recommended name
    ATP-dependent Clp protease proteolytic subunit
  • EC number
  • Alternative names
    • Endopeptidase Clp

Gene names

    • Name
      clpP

Encoded on

  • Chloroplast

Organism names

  • Taxonomic identifier
  • Strain
    • cv. B73
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > Liliopsida > Poales > Poaceae > PACMAD clade > Panicoideae > Andropogonodae > Andropogoneae > Tripsacinae > Zea

Accessions

  • Primary accession
    P26567

Proteomes

Organism-specific databases

Subcellular Location

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00001797431-216ATP-dependent Clp protease proteolytic subunit

Proteomic databases

Expression

Gene expression databases

Interaction

Subunit

Component of the chloroplastic Clp protease core complex.

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the peptidase S14 family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    216
  • Mass (Da)
    24,759
  • Last updated
    1995-11-01 v2
  • Checksum
    F85B11C5A4D48159
MPIGVPKVPYRIPGDEEATWVDLYNVMYRERTLFLGQEIRCEITNHITGLMVYLSIEDGNSDIFLFINSLGGWLISGMAIFDTMQTVTPDIYTICLGIAASMASFILLGGEPTKRIAFPHARIMLHQPASAYYRARTPEFLLEVEELHKVREMITRVYALRTGKPFWVVSEDMERDVFMSADEAKAYGLVDIVGDEMIDEHCDTDPVWFPEMFKDW

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
X86563
EMBL· GenBank· DDBJ
CAA60310.1
EMBL· GenBank· DDBJ
Genomic DNA
X60548
EMBL· GenBank· DDBJ
CAA43038.1
EMBL· GenBank· DDBJ
Genomic DNA
M17842
EMBL· GenBank· DDBJ
AAA85358.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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