P26338 · CYAA_TRYEQ

  • Protein
    Receptor-type adenylate cyclase
  • Gene
    ESAG4C
  • Status
    UniProtKB reviewed (Swiss-Prot)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    4/5

Function

function

Could act as a receptor for an unknown ligand.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Note: Binds 1 Mg2+ ion per subunit.

Features

Showing features for binding site.

146950100150200250300350400450
TypeIDPosition(s)Description
Binding site108Mg2+ (UniProtKB | ChEBI)
Binding site151Mg2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functionadenylate cyclase activity
Molecular FunctionATP binding
Molecular Functionmetal ion binding
Biological ProcesscAMP biosynthetic process
Biological Processintracellular signal transduction

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Receptor-type adenylate cyclase
  • EC number
  • Alternative names
    • ATP pyrophosphate-lyase
    • Adenylyl cyclase

Gene names

    • Name
      ESAG4C

Organism names

  • Taxonomic identifier
  • Strain
    • CL
  • Taxonomic lineage
    Eukaryota > Discoba > Euglenozoa > Kinetoplastea > Metakinetoplastina > Trypanosomatida > Trypanosomatidae > Trypanosoma

Accessions

  • Primary accession
    P26338

Organism-specific databases

Subcellular Location

Cell membrane
; Multi-pass membrane protein

Features

Showing features for topological domain, transmembrane.

TypeIDPosition(s)Description
Topological domain1-59Extracellular
Transmembrane60-80Helical
Topological domain81-469Cytoplasmic

Keywords

PTM/Processing

Features

Showing features for chain, glycosylation.

TypeIDPosition(s)Description
ChainPRO_00001957411-469Receptor-type adenylate cyclase
Glycosylation31N-linked (GlcNAc...) asparagine

Keywords

PTM databases

Structure

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain103-257Guanylate cyclase

Sequence similarities

Belongs to the adenylyl cyclase class-3 family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    469
  • Mass (Da)
    50,819
  • Last updated
    1992-05-01 v1
  • Checksum
    F87638C3152DEA3A
VDTAEKLSKNGCASNYGATQISVWSMARALNASIPPLTNPMTPSMTFRNSNAGRISGVALVGVIIGGALALFLVVALGVVPYFFLHNTRDNNLAPKELTDPVTLIFTDIESSTALWAAHPELMPDAVATHHRLIRSLIGRYGCYEVKTVGDSFMIASKSPFAAVQLAQELQLCFLHHDWGTNAIDESYQQLEQQRAEEDAKYTPPTARLDLKVYSRLWNGLRVRVGIHTGLCDIRRDEVTKGYDYYGRTSNMAARTESVGNGGQVLMTTAAYMSLSAEEREQIDVTALGDVPLRGVAKPVEMYQLNAVPGRTFAGLRLEHELLNDDEDQTTTSCSDHSSSRTDLSVAAQTIAASLQSLLGTFTPAQRQKALIPFCERWRVPLPQKVGNVWDNDGCQEAIRRVAAKVGRVMDFGTRKASSSVTSLERGGSLFSAGGATVATVASSSNFSCVDGRCGTVQLIDLENDSTTS

Features

Showing features for non-terminal residue.

TypeIDPosition(s)Description
Non-terminal residue1

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
X59386
EMBL· GenBank· DDBJ
CAA42029.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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