P24944 · GLTT_BACCA
- ProteinProton/sodium-glutamate symport protein
- GenegltT
- StatusUniProtKB reviewed (Swiss-Prot)
- Organism
- Amino acids421 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score3/5
Function
function
This carrier protein is part of the Na+-dependent, binding-protein-independent glutamate-aspartate transport system.
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | symporter activity | |
Biological Process | carboxylic acid transport |
Keywords
- Biological process
Names & Taxonomy
Protein names
- Recommended nameProton/sodium-glutamate symport protein
- Alternative names
Gene names
Organism names
- Organism
- Taxonomic lineageBacteria > Bacillota > Bacilli > Bacillales > Bacillaceae > Geobacillus > Geobacillus thermoleovorans group
Accessions
- Primary accessionP24944
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Multi-pass membrane protein
Features
Showing features for topological domain, transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Topological domain | 1-3 | Cytoplasmic | ||||
Sequence: MRK | ||||||
Transmembrane | 4-24 | Helical | ||||
Sequence: IGLAWQIFIGLILGIIVGAIF | ||||||
Topological domain | 25-43 | Extracellular | ||||
Sequence: YGNPKVAAYLQPIGDIFLR | ||||||
Transmembrane | 44-64 | Helical | ||||
Sequence: LIKMIVIPIVISSLVVGVASV | ||||||
Topological domain | 65-77 | Cytoplasmic | ||||
Sequence: GDLKKLGKLGGKT | ||||||
Transmembrane | 78-98 | Helical | ||||
Sequence: IIYFEIITTIAIVVGLLAANI | ||||||
Topological domain | 99-148 | Extracellular | ||||
Sequence: FQPGAGVNMKSLEKTDIQSYVDTTNEVQHHSMVETFVNIVPKNIFESLST | ||||||
Transmembrane | 149-169 | Helical | ||||
Sequence: GDMLPIIFFSVMFGLGVAAIG | ||||||
Topological domain | 170-198 | Cytoplasmic | ||||
Sequence: EKGKPVLQFFQGTAEAMFYVTNQIMKFAP | ||||||
Transmembrane | 199-219 | Helical | ||||
Sequence: FGVFALIGVTVSKFGVESLIP | ||||||
Topological domain | 220-222 | Extracellular | ||||
Sequence: LSK | ||||||
Transmembrane | 223-243 | Helical | ||||
Sequence: LVIVVYATMLFFIFAVLGGVA | ||||||
Topological domain | 244 | Cytoplasmic | ||||
Sequence: K | ||||||
Transmembrane | 245-265 | Helical | ||||
Sequence: LFGINIFHIIKILKDELILAY | ||||||
Topological domain | 266-306 | Extracellular | ||||
Sequence: STASSETVLPRIMDKMEKFGCPKAITSFVIPTGYSFNLDGS | ||||||
Transmembrane | 307-327 | Helical | ||||
Sequence: TLYQALAAIFIAQLYGIDMSV | ||||||
Topological domain | 328-330 | Cytoplasmic | ||||
Sequence: SQQ | ||||||
Transmembrane | 331-351 | Helical | ||||
Sequence: ISLLLVLMVTSKGIAGVPGVS | ||||||
Transmembrane | 352-372 | Helical | ||||
Sequence: FVVLLATLGTVGIPVEGLAFI | ||||||
Topological domain | 373-421 | Cytoplasmic | ||||
Sequence: AGIDRILDMARTAVNVIGNSLAAIIMSKWEGQYNEEKGKQYLAELQQSA |
Keywords
- Cellular component
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000202086 | 1-421 | Proton/sodium-glutamate symport protein | |||
Sequence: MRKIGLAWQIFIGLILGIIVGAIFYGNPKVAAYLQPIGDIFLRLIKMIVIPIVISSLVVGVASVGDLKKLGKLGGKTIIYFEIITTIAIVVGLLAANIFQPGAGVNMKSLEKTDIQSYVDTTNEVQHHSMVETFVNIVPKNIFESLSTGDMLPIIFFSVMFGLGVAAIGEKGKPVLQFFQGTAEAMFYVTNQIMKFAPFGVFALIGVTVSKFGVESLIPLSKLVIVVYATMLFFIFAVLGGVAKLFGINIFHIIKILKDELILAYSTASSETVLPRIMDKMEKFGCPKAITSFVIPTGYSFNLDGSTLYQALAAIFIAQLYGIDMSVSQQISLLLVLMVTSKGIAGVPGVSFVVLLATLGTVGIPVEGLAFIAGIDRILDMARTAVNVIGNSLAAIIMSKWEGQYNEEKGKQYLAELQQSA |
Interaction
Subunit
Homotrimer.
Structure
Sequence
- Sequence statusComplete
- Length421
- Mass (Da)45,345
- Last updated1992-03-01 v1
- Checksum10ABBE12EDD1E7E4