Testicular macrophages are recruited during a narrow fetal time window and promote organ-specific developmental functions.Gu X., Heinrich A., Li S.Y., DeFalco T.View abstractCategoriesFunction, ExpressionSourceMGI: 96233PubMedEurope PMCNat Commun 14:1439-1439 (2023)Mapped to99+
Targeted Disruption of Lats1 and Lats2 in Mice Impairs Testis Development and Alters Somatic Cell Fate.Abou Nader N., Menard A., Levasseur A., St-Jean G., Boerboom D., Zamberlam G., Boyer A.View abstractCategoriesFunction, ExpressionSourceMGI: 96233PubMedEurope PMCInt J Mol Sci 23:13585-13585 (2022)Mapped to99+
TRIM28-dependent SUMOylation protects the adult ovary from activation of the testicular pathway.Rossitto M., Dejardin S., Rands C.M., Le Gras S., Migale R., Rafiee M.R., Neirijnck Y., Pruvost A., Nguyen A.L.[...], Poulat F.View abstractCategoriesFunction, ExpressionSourceMGI: 96233PubMedEurope PMCNat Commun 13:4412-4412 (2022)Mapped to83
Deletion of Wt1 during early gonadogenesis leads to differences of sex development in male and female adult mice.Torres-Cano A., Portella-Fortuny R., Muller-Sanchez C., Porras-Marfil S., Ramiro-Pareta M., Chau Y.Y., Reina M., Soriano F.X., Martinez-Estrada O.M.View abstractCategoriesFunction, ExpressionSourceMGI: 96233PubMedEurope PMCPLoS Genet 18:e1010240-e1010240 (2022)Mapped to99
An essential role for Polycomb Repressive Complex 2 in the mouse ovary.Prokopuk L., Jarred E.G., Blucher R.O., McLaughlin E.A., Stringer J.M., Western P.S.View abstractCategoriesFunctionSourceMGI: 96233PubMedEurope PMCReproduction 163:167-182 (2022)Mapped to99+
Constitutive expression of Steroidogenic factor-1 (NR5A1) disrupts ovarian functions, fertility, and metabolic homeostasis in female mice.Rotgers E., Nicol B., Rodriguez K., Rattan S., Flaws J.A., Yao H.H.View abstractCategoriesFunctionSourceMGI: 96233PubMedEurope PMCFASEB J 35:e21770-e21770 (2021)Mapped to88
Loss of Mafb and Maf distorts myeloid cell ratios and disrupts fetal mouse testis vascularization and organogenesis†.Li S.Y., Gu X., Heinrich A., Hurley E.G., Capel B., DeFalco T.View abstractCategoriesFunction, ExpressionSourceMGI: 96233PubMedEurope PMCBiol Reprod 105:958-975 (2021)Mapped to99+
Excess of ovarian nerve growth factor impairs embryonic development and causes reproductive and metabolic dysfunction in adult female mice.Manti M., Pui H.P., Edstrom S., Risal S., Lu H., Lindgren E., Ohlsson C., Jerlhag E., Benrick A.[...], Stener-Victorin E.View abstractCategoriesFunctionSourceMGI: 96233PubMedEurope PMCFASEB J 34:14440-14457 (2020)Mapped to99+
Activin A Determines Steroid Levels and Composition in the Fetal Testis.Whiley P.A.F., O'Donnell L., Moody S.C., Handelsman D.J., Young J.C., Richards E.A., Almstrup K., Western P.S., Loveland K.L.View abstractCategoriesFunction, ExpressionSourceMGI: 96233PubMedEurope PMCEndocrinology 161:bqaa058-bqaa058 (2020)Mapped to99+
Steroidogenic differentiation and PKA signaling are programmed by histone methyltransferase EZH2 in the adrenal cortex.Mathieu M., Drelon C., Rodriguez S., Tabbal H., Septier A., Damon-Soubeyrand C., Dumontet T., Berthon A., Sahut-Barnola I.[...], Val P.View abstractCategoriesFunctionSourceMGI: 96233PubMedEurope PMCProc Natl Acad Sci U S A 115:E12265-E12274 (2018)Mapped to99+
Fetal Leydig cells dedifferentiate and serve as adult Leydig stem cells.Shima Y., Miyabayashi K., Sato T., Suyama M., Ohkawa Y., Doi M., Okamura H., Suzuki K.View abstractCategoriesFunction, ExpressionSourceMGI: 96233PubMedEurope PMCDevelopment 145:dev169136-dev169136 (2018)Mapped to59
A perivascular niche for multipotent progenitors in the fetal testis.Kumar D.L., DeFalco T.View abstractCategoriesFunction, ExpressionSourceMGI: 96233PubMedEurope PMCNat Commun 9:4519-4519 (2018)Mapped to69
Forebrain Ptf1a Is Required for Sexual Differentiation of the Brain.Fujiyama T., Miyashita S., Tsuneoka Y., Kanemaru K., Kakizaki M., Kanno S., Ishikawa Y., Yamashita M., Owa T.[...], Hoshino M.View abstractCategoriesFunction, Expression, Phenotypes & VariantsSourceMGI: 96233PubMedEurope PMCCell Rep 24:79-94 (2018)Mapped to99+
MRAP deficiency impairs adrenal progenitor cell differentiation and gland zonation.Novoselova T.V., Hussain M., King P.J., Guasti L., Metherell L.A., Charalambous M., Clark A.J.L., Chan L.F.View abstractCategoriesFunction, ExpressionSourceMGI: 96233PubMedEurope PMCFASEB J 0:fj201701274RR-fj201701274RR (2018)Mapped to99+
Elimination of the male reproductive tract in the female embryo is promoted by COUP-TFII in mice.Zhao F., Franco H.L., Rodriguez K.F., Brown P.R., Tsai M.J., Tsai S.Y., Yao H.H.View abstractCategoriesFunctionSourceMGI: 96233PubMedEurope PMCScience 357:717-720 (2017)Mapped to99+
The transcription factor GATA4 is required for follicular development and normal ovarian function.Efimenko E., Padua M.B., Manuylov N.L., Fox S.C., Morse D.A., Tevosian S.G.View abstractCategoriesFunctionSourceMGI: 96233PubMedEurope PMCDev Biol 381:144-158 (2013)Mapped to64
In vivo evidence for the crucial role of SF1 in steroid-producing cells of the testis, ovary and adrenal gland.Buaas F.W., Gardiner J.R., Clayton S., Val P., Swain A.View abstractCategoriesFunction, ExpressionSourceMGI: 96233PubMedEurope PMCDevelopment 139:4561-4570 (2012)Mapped to65
Loss of Wnt5a disrupts primordial germ cell migration and male sexual development in mice.Chawengsaksophak K., Svingen T., Ng E.T., Epp T., Spiller C.M., Clark C., Cooper H., Koopman P.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 96233PubMedEurope PMCBiol Reprod 86:1-12 (2012)Mapped to59
Eliminating SF-1 (NR5A1) sumoylation in vivo results in ectopic hedgehog signaling and disruption of endocrine development.Lee F.Y., Faivre E.J., Suzawa M., Lontok E., Ebert D., Cai F., Belsham D.D., Ingraham H.A.View abstractCategoriesFunctionSourceMGI: 96233PubMedEurope PMCDev Cell 21:315-327 (2011)Mapped to99+
Ovarian development in mice requires the GATA4-FOG2 transcription complex.Manuylov N.L., Smagulova F.O., Leach L., Tevosian S.G.View abstractCategoriesFunctionSourceMGI: 96233PubMedEurope PMCDevelopment 135:3731-3743 (2008)Mapped to99+
R-spondin1 plays an essential role in ovarian development through positively regulating Wnt-4 signaling.Tomizuka K., Horikoshi K., Kitada R., Sugawara Y., Iba Y., Kojima A., Yoshitome A., Yamawaki K., Amagai M.[...], Kakitani M.View abstractCategoriesFunctionSourceMGI: 96233PubMedEurope PMCHum Mol Genet 17:1278-1291 (2008)Mapped to58
The regulation of Sox9 gene expression by the GATA4/FOG2 transcriptional complex in dominant XX sex reversal mouse models.Manuylov N.L., Fujiwara Y., Adameyko I.I., Poulat F., Tevosian S.G.View abstractCategoriesFunction, InteractionSourceMGI: 96233PubMedEurope PMCDev Biol 307:356-367 (2007)Mapped to56
Genetic determinants modulate susceptibility to pregnancy-associated tumourigenesis in a recombinant line of Min mice.Suraweera N., Haines J., McCart A., Rogers P., Latchford A., Coster M., Polanco-Echeverry G., Guenther T., Wang J.[...], Silver A.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 96233PubMedEurope PMCHum Mol Genet 15:3429-3435 (2006)Mapped to54
Gonadal sex reversal in mutant Dax1 XY mice: a failure to upregulate Sox9 in pre-Sertoli cells.Bouma G.J., Albrecht K.H., Washburn L.L., Recknagel A.K., Churchill G.A., Eicher E.M.View abstractCategoriesFunction, ExpressionSourceMGI: 96233PubMedEurope PMCDevelopment 132:3045-3054 (2005)Mapped to99+
Gonadal differentiation, sex determination and normal Sry expression in mice require direct interaction between transcription partners GATA4 and FOG2.Tevosian S.G., Albrecht K.H., Crispino J.D., Fujiwara Y., Eicher E.M., Orkin S.H.View abstractCategoriesFunctionSourceMGI: 96233PubMedEurope PMCDevelopment 129:4627-4634 (2002)Cited in1Mapped to80