P23924 · MGLA_SALTY

Function

function

Part of the ABC transporter complex MglABC involved in galactose/methyl galactoside import. Responsible for energy coupling to the transport system.

Catalytic activity

Activity regulation

Stimulated 3-fold by galactose and inhibited by vanadate, N-ethylmaleimide, and 5-methoxyindole-2-carboxylic acid.

Kinetics

KM SUBSTRATE pH TEMPERATURE[C] NOTES EVIDENCE
60 μMATP
Vmax pH TEMPERATURE[C] NOTES EVIDENCE
140 nmol/min/mg

pH Dependence

Optimum pH is about 8.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site46-53ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular FunctionATP binding
Molecular FunctionATP hydrolysis activity

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Galactose/methyl galactoside import ATP-binding protein MglA
  • EC number

Gene names

    • Name
      mglA
    • Ordered locus names
      STM2189

Organism names

Accessions

  • Primary accession
    P23924

Proteomes

Subcellular Location

Cell inner membrane
; Peripheral membrane protein

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00000925131-506Galactose/methyl galactoside import ATP-binding protein MglA

Proteomic databases

Interaction

Subunit

The complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB).

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain14-249ABC transporter 1
Domain259-506ABC transporter 2

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    506
  • Mass (Da)
    56,477
  • Last updated
    1997-11-01 v2
  • Checksum
    F5B709311B0E6168
MGSTISPPSGEYLLEMRGINKSFPGVKALDNVNLNVRPHSIHALMGENGAGKSTLLKCLFGIYQKDSGSIVFQGKEVDFHSAKEALENGISMVHQELNLVLQRSVMDNMWLGRYPTKGMFVDQDKMYQDTKAIFDELDIDIDPRARVGTLSVSQMQMIEIAKAFSYNAKIVIMDEPTSSLTEKEVNHLFTIIRKLKERGCGIVYISHKMEEIFQLCDEITILRDGQWIATQPLEGLDMDKIIAMMVGRSLNQRFPDKENKPGDVILEVRHLTSLRQPSIRDVSFDLHKGEILGIAGLVGAKRTDIVETLFGIREKSSGTITLHGKKINNHTANEAINHGFALVTEERRSTGIYAYLDIGFNSLISNIRNYKNKVGLLDNSRMKSDTQWVIDSMRVKTPGHRTQIGSLSGGNQQKVIIGRWLLTQPEILMLDEPTRGIDVGAKFEIYQLIAELAKKGKGIIIISSEMPELLGITDRILVMSNGLVSGIVDTKTTTQNEILRLASLHL

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
U40492
EMBL· GenBank· DDBJ
AAC44149.1
EMBL· GenBank· DDBJ
Genomic DNA
AE006468
EMBL· GenBank· DDBJ
AAL21093.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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