Cloning, expression, pharmacology and regulation of a delayed rectifier K+ channel in mouse heart.Honore E., Attali B., Romey G., Heurteaux C., Ricard P., Lesage F., Lazdunski M., Barhanin J.View abstractCited forNUCLEOTIDE SEQUENCE [MRNA], PARTIAL PROTEIN SEQUENCETissueHeartCategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCEMBO J. 10:2805-2811 (1991)Cited in1Mapped to1
ISK, a slowly activating voltage-sensitive K+ channel. Characterization of multiple cDNAs and gene organization in the mouse.Lesage F., Attali B., Lazdunski M., Barhanin J.View abstractCited forNUCLEOTIDE SEQUENCE [MRNA]CategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCFEBS Lett. 301:168-172 (1992)Cited in1Mapped to1
The transcriptional landscape of the mammalian genome.Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B.[...], Hayashizaki Y.View abstractCited forNUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]StrainC57BL/6JTissueSkinCategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCScience 309:1559-1563 (2005)Cited in99+16Mapped to99+
K(V)LQT1 and IsK (minK) proteins associate to form the I(Ks) cardiac potassium current.Barhanin J., Lesage F., Guillemare E., Fink M., Lazdunski M., Romey G.View abstractCited forINTERACTION WITH KCNQ1TissueHeartCategoriesInteractionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCNature 384:78-80 (1996)Cited in2Mapped to11
Replacement by homologous recombination of the minK gene with lacZ reveals restriction of minK expression to the mouse cardiac conduction system.Kupershmidt S., Yang T., Anderson M.E., Wessels A., Niswender K.D., Magnuson M.A., Roden D.M.View abstractCategoriesSequencesSourceMGI: 96673PubMedEurope PMCCirc Res 84:146-152 (1999)Mapped to2
Adult KCNE1-knockout mice exhibit a mild cardiac cellular phenotype.Charpentier F., Merot J., Riochet D., Le Marec H., Escande D.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 96673PubMedEurope PMCBiochem Biophys Res Commun 251:806-810 (1998)Mapped to2
Involvement of IsK-associated K+ channel in heart rate control of repolarization in a murine engineered model of Jervell and Lange-Nielsen syndrome.Drici M.D., Arrighi I., Chouabe C., Mann J.R., Lazdunski M., Romey G., Barhanin J.View abstractCategoriesSequencesSourceMGI: 96673PubMedEurope PMCCirc Res 83:95-102 (1998)Mapped to2
Properties of KvLQT1 K+ channel mutations in Romano-Ward and Jervell and Lange-Nielsen inherited cardiac arrhythmias.Chouabe C., Neyroud N., Guicheney P., Lazdunski M., Romey G., Barhanin J.View abstractCategoriesSequencesSourceMGI: 96673PubMedEurope PMCEMBO J. 16:5472-5479 (1997)Cited in2Mapped to2
High-resolution recombinational map of mouse chromosome 16.Reeves R.H., Rue E.E., Citron M.P., Cabin D.E.View abstractCategoriesSequencesSourceMGI: 96673PubMedEurope PMCGenomics 43:202-208 (1997)Mapped to99+
Inner ear defects induced by null mutation of the isk gene.Vetter D.E., Mann J.R., Wangemann P., Liu J., McLaughlin K.J., Lesage F., Marcus D.C., Lazdunski M., Heinemann S.F., Barhanin J.View abstractCategoriesFunction, SequencesSourceMGI: 96673PubMedEurope PMCNeuron 17:1251-1264 (1996)Mapped to2
Differential expression of Isk mRNAs in mouse tissue during development and pregnancy.Felipe A., Knittle T.J., Doyle K.L., Snyders D.J., Tamkun M.M.View abstractCategoriesSequencesSourceMGI: 96673PubMedEurope PMCAm J Physiol 267:C700-5 (1994)Mapped to2
Genetic determinants of micronucleus formation in vivo.Adams D.J., Barlas B., McIntyre R.E., Salguero I., van der Weyden L., Barros A., Vicente J.R., Karimpour N., Haider A.[...], White J.K.View abstractSourceMGI: 96673PubMedEurope PMCNature 627:130-136 (2024)Mapped to99+
KCNE1 does not shift TMEM16A from a Ca<sup>2+</sup> dependent to a voltage dependent Cl<sup>-</sup> channel and is not expressed in renal proximal tubule.Talbi K., Ousingsawat J., Centeio R., Schreiber R., Kunzelmann K.View abstractAnnotationKCNE1 does not shift TMEM16A from a Ca[2+]SourceGeneRif: 16509PubMedEurope PMCPflugers Arch 475:995-1007 (2023)Mapped to6
TCF7L1 Controls the Differentiation of Tuft Cells in Mouse Small Intestine.Zinina V.V., Sauer M., Nigmatullina L., Kreim N., Soshnikova N.View abstractSourceMGI: 96673PubMedEurope PMCCells 12:1452-1452 (2023)Mapped to72
<i>LAMP2</i> Cardiomyopathy: Consequences of Impaired Autophagy in the Heart.Alcalai R., Arad M., Wakimoto H., Yadin D., Gorham J., Wang L., Burns E., Maron B.J., Roberts W.C.[...], Seidman C.E.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 96673PubMedEurope PMCJ Am Heart Assoc 10:e018829-e018829 (2021)Mapped to8
Elevation of propofol sensitivity of cardiac I<sub>Ks</sub> channel by KCNE1 polymorphism D85N.Kojima A., Mi X., Fukushima Y., Ding W.G., Omatsu-Kanbe M., Matsuura H.View abstractAnnotationElevation of propofol sensitivity of cardiac IKs channel by KCNE1 polymorphism D85N.SourceGeneRif: 16509PubMedEurope PMCBr J Pharmacol 178:2690-2708 (2021)Mapped to2
Gene therapy via canalostomy approach preserves auditory and vestibular functions in a mouse model of Jervell and Lange-Nielsen syndrome type 2.Wu X., Zhang L., Li Y., Zhang W., Wang J., Cai C., Lin X.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 96673PubMedEurope PMCNat Commun 12:697-697 (2021)Mapped to2
KCNE1 is an auxiliary subunit of two distinct ion channel superfamilies.Avalos Prado P., Hafner S., Comoglio Y., Wdziekonski B., Duranton C., Attali B., Barhanin J., Sandoz G.View abstractAnnotationKCNE1 is an auxiliary subunit of two distinct ion channel superfamilies.CategoriesFunctionSourceGeneRif: 16509, MGI: 96673PubMedEurope PMCCell 184:534-544.e11 (2021)Mapped to9
Mechanism Sharing Between Genetic and Gestational Hypoxia-Induced Cardiac Anomalies.Moumne O., Chowdhurry R., Doll C., Pereira N., Hashimi M., Grindrod T., Dollar J.J., Riva A., Kasahara H.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 96673PubMedEurope PMCFront Cardiovasc Med 5:100-100 (2018)Mapped to64
SUMOylation determines the voltage required to activate cardiac <i>I</i><sub><i>Ks</i></sub> channels.Xiong D., Li T., Dai H., Arena A.F., Plant L.D., Goldstein S.A.N.View abstractAnnotationSUMOylation of KCNQ1 is KCNE1 dependent and determines the native attributes of cardiac IKs in vivo.CategoriesPTM / ProcessingSourceGeneRif: 16509PubMedEurope PMCProc Natl Acad Sci U S A 114:E6686-E6694 (2017)Mapped to9
Remodeling of repolarization and arrhythmia susceptibility in a myosin- binding protein C knockout mouse model.Toib A., Zhang C., Borghetti G., Zhang X., Wallner M., Yang Y., Troupes C.D., Kubo H., Sharp T.E.[...], Houser S.R.View abstractCategoriesPhenotypes & VariantsSourceMGI: 96673PubMedEurope PMCAm J Physiol Heart Circ Physiol 313:H620-H630 (2017)Mapped to25
Myocardial VHL-HIF Signaling Controls an Embryonic Metabolic Switch Essential for Cardiac Maturation.Menendez-Montes I., Escobar B., Palacios B., Gomez M.J., Izquierdo-Garcia J.L., Flores L., Jimenez-Borreguero L.J., Aragones J., Ruiz-Cabello J.[...], Martin-Puig S.View abstractCategoriesFunctionSourceMGI: 96673PubMedEurope PMCDev Cell 39:724-739 (2016)Mapped to99+
BACE1 modulates gating of KCNQ1 (Kv7.1) and cardiac delayed rectifier KCNQ1/KCNE1 (IKs).Agsten M., Hessler S., Lehnert S., Volk T., Rittger A., Hartmann S., Raab C., Kim D.Y., Groemer T.W.[...], Huth T.View abstractAnnotationThe electrophysiological effects of BACE1 on KCNQ1 reported here were independent of its enzymatic activity.CategoriesInteractionSourceGeneRif: 16509, MGI: 96673PubMedEurope PMCJ Mol Cell Cardiol 89:335-348 (2015)Mapped to21
KCNE1 and KCNE3: The yin and yang of voltage-gated K(+) channel regulation.Abbott G.W.View abstractAnnotationKCNE1 and KCNE3: The yin and yang of voltage-gated K(+) channel regulationCategoriesFunction, InteractionSourceGeneRif: 16509PubMedEurope PMCGene 576:1-13 (2016)Mapped to14
MyoR modulates cardiac conduction by repressing Gata4.Harris J.P., Bhakta M., Bezprozvannaya S., Wang L., Lubczyk C., Olson E.N., Munshi N.V.View abstractCategoriesFunction, InteractionSourceMGI: 96673PubMedEurope PMCMol Cell Biol 35:649-661 (2015)Mapped to36