P22648 · FAS2_SCHAM

Function

function

Neuronal recognition molecule. Involved in a pathway recognition for axons during the development of nerve fascicles.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentmembrane
Biological Processanatomical structure morphogenesis
Biological Processcell adhesion
Biological Processcell differentiation
Biological Processnervous system development

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Fasciclin-2
  • Alternative names
    • Fasciclin II (FAS II)

Gene names

    • Name
      FAS2

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Polyneoptera > Orthoptera > Caelifera > Acrididea > Acridomorpha > Acridoidea > Acrididae > Cyrtacanthacridinae > Schistocerca

Accessions

  • Primary accession
    P22648

Subcellular Location

Membrane ; Single-pass type I membrane protein

Features

Showing features for topological domain, transmembrane.

TypeIDPosition(s)Description
Topological domain23-764Extracellular
Transmembrane765-782Helical
Topological domain783-898Cytoplasmic

Keywords

PTM/Processing

Features

Showing features for signal, chain, glycosylation, disulfide bond.

TypeIDPosition(s)Description
Signal1-22
ChainPRO_000001475923-898Fasciclin-2
Glycosylation35N-linked (GlcNAc...) asparagine
Disulfide bond48↔113
Glycosylation51N-linked (GlcNAc...) asparagine
Glycosylation149N-linked (GlcNAc...) asparagine
Disulfide bond156↔203
Glycosylation192N-linked (GlcNAc...) asparagine
Disulfide bond248↔300
Glycosylation297N-linked (GlcNAc...) asparagine
Glycosylation328N-linked (GlcNAc...) asparagine
Disulfide bond343↔407
Glycosylation447N-linked (GlcNAc...) asparagine
Disulfide bond450↔509
Glycosylation457N-linked (GlcNAc...) asparagine
Glycosylation580N-linked (GlcNAc...) asparagine

Keywords

PTM databases

Structure

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain31-124Ig-like C2-type 1
Domain134-219Ig-like C2-type 2
Domain226-316Ig-like C2-type 3
Domain321-423Ig-like C2-type 4
Domain428-525Ig-like C2-type 5
Domain532-626Fibronectin type-III 1
Domain644-745Fibronectin type-III 2

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    898
  • Mass (Da)
    99,065
  • Last updated
    1994-02-01 v2
  • Checksum
    07989EA4F39604AC
MRTVACAVLLACFMGCLAGAWAQSAGLEILPNSENQTKPIGRSMLLTCKPNVTNKNLISQLRWTDPSGREVPFKNPTLLKPHIFVDWLPPPGEKVLTLMIPELREADTGTYTCSALYSNTKQLSKSVHVRTIMPITWDDAPEEQYPTVNETFKIRCRVSANPPAIVNWMRDGHIVETGDRYVVEQDGLTILNVTEMDDGTYTCRAIVIATGEMALRPIRVEVHTPPQMSGALPPKLEAVEGTDFTAKCAASGKPVPRYTWIRVDTARDLTKDGDRVSADVLLGELRIREVRPEDAANYSCTAKNAAGTATATVEVTVVVRPRIGRFDNISVASGKDSEAVLECHATGSPLPAVTFRKLSNPNRYINGIQPTEDRITVDGVDSPDGRTRIGKLIISNVLRSDDGLYECIATNKGGEVKKNGHLMVEFKPSFADTPQKEVWGWEQHAVNLTCLAHSIPNATISWHFNGADLFRGREGQELQQTGYTLFGSGPRSTLQVIPFNRKMYGNYKCTATNKHGTAVHEIMLREARVPSAVLQVKMDVMTATTVTFKFFGPGNDGGLPTKNYAVQYKQDSQGWEDALNRTWPVDSPYILENLKPQTRYNFRFAAQNEVGFGPWSSQQTHTTPRISAPEEPRLLGLPLSATSGTENEVVVSPYPNRYELRWQVPADNGEPITHYSVKSCPVEKYDTEWRLLPYPCQEHKLEGQATTFQLESLQPDTHYKVEVRATNAIGNSVPGQIIVRTVKDPSQMPGVANVEDGSEGQMSSAAIVVLVVAALLLALLVVDLVCCLVWRGGLIAALCHRCCSAAKTDDSDAKIASLYSWRFPLPYCSNKEDPAMLAPAKMQQATVKIPVIEEKEPLRDGKEPVPIIKERVKRETAVDFDVKKSVSRTSFVGKDSAV

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
J03789
EMBL· GenBank· DDBJ
AAA29810.1
EMBL· GenBank· DDBJ
mRNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp