P21822 · MCPS_KLEAK

Function

function

Receptor for the attractant L-serine and related amino acids.
Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of methylation. Attractants increase the level of methylation while repellents decrease the level of methylation, the methyl groups are added by the methyltransferase CheR and removed by the methylesterase CheB.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentplasma membrane
Molecular Functiontransmembrane signaling receptor activity
Biological Processchemotaxis
Biological Processsignal transduction

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Methyl-accepting chemotaxis serine transducer

Gene names

    • Name
      tse
    • Ordered locus names
      EAE_15535

Organism names

Accessions

  • Primary accession
    P21822
  • Secondary accessions
    • G0DZQ6

Proteomes

Subcellular Location

Features

Showing features for topological domain, transmembrane.

TypeIDPosition(s)Description
Topological domain1-9Cytoplasmic
Transmembrane10-30Helical
Topological domain31-191Periplasmic
Transmembrane192-212Helical
Topological domain213-556Cytoplasmic

Keywords

PTM/Processing

Features

Showing features for chain, modified residue.

TypeIDPosition(s)Description
ChainPRO_00001105431-556Methyl-accepting chemotaxis serine transducer
Modified residue297Glutamate methyl ester (Gln)
Modified residue304Glutamate methyl ester (Glu)
Modified residue311Glutamate methyl ester (Gln)
Modified residue493Glutamate methyl ester (Glu)
Modified residue502Glutamate methyl ester (Glu)

Keywords

Structure

Family & Domains

Features

Showing features for region, domain.

TypeIDPosition(s)Description
Region64-73The 3 Arg may form a positively charged pocket, which binds the alpha-carboxyl group of the attractant AA
Domain216-268HAMP
Domain273-502Methyl-accepting transducer

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    556
  • Mass (Da)
    60,038
  • Last updated
    2011-12-14 v2
  • Checksum
    F2DE0FCA1865C9A5
MFNRIKVVTSLLLVLVLFGALQLISGGLFFSSLKSDKENFTVLQTIRQQQLLLSESRVDLLQARNSLNRAGIRYMMDTNKIGSGATIDELLAKAKEELARAERNYTAYEKIPQDPRQDPQATEKLKQQYGILYGALSELIQLLGEGKINAFFDQPTQKYQDDFEQTYNAYLQQNGKLYQIAVDASNSSYSSAIWTLIVVIIVVLAAIVGVWMGIHHILVRPLNRMIEHIKRIASGDLTQPIPVTSRNEIGVLAASLKHMQNELIETVSGVRQGADAIYSGASEIAAGNNDLSSRTEQQAASLEETAASMEQLTATVKQNAENARQASQLALSASETAQKGGKVVANVVETMHDIASSSQKIADITGVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRNLAQRSAQAAKEIKALIEDSVNRVDMGSVLVESAGDTMGDIVNAVTRVTDIMGEIASASDEQSRGIDQVGQAVAEMDRVTQQNASLVEESASAAAALEEQASLLTQSVAVFRLKSEGQEEYKAPVSNKTAPAAIATHKKTSASDYQDNWETF

Features

Showing features for sequence conflict.

TypeIDPosition(s)Description
Sequence conflict35in Ref. 1; AAA24797
Sequence conflict94in Ref. 1; AAA24797
Sequence conflict97in Ref. 1; AAA24797
Sequence conflict145-146in Ref. 1; AAA24797
Sequence conflict276-279in Ref. 1; AAA24797
Sequence conflict284in Ref. 1; AAA24797
Sequence conflict301in Ref. 1; AAA24797
Sequence conflict370in Ref. 1; AAA24797
Sequence conflict395in Ref. 1; AAA24797
Sequence conflict478in Ref. 1; AAA24797
Sequence conflict500in Ref. 1; AAA24797

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
M26411
EMBL· GenBank· DDBJ
AAA24797.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002824
EMBL· GenBank· DDBJ
AEG98018.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp