P21339 · MSB1_YEAST
- ProteinMorphogenesis-related protein MSB1
- GeneMSB1
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids1137 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score3/5
Variants
Variant ID(s) | Position(s) | Change | Description | Clinical significance | Provenance | ||
---|---|---|---|---|---|---|---|
s15-685841 | 25 | K>I | SGRP | ||||
Consequence: missense Predictions: - SIFT: deleterious - low confidence (0.01) Somatic: No Accession: XV:g.685840A>T Codon: AAA/ATA Consequence type: missense Cytogenetic band: Genomic location: XV:g.685840A>T Locations: - p.Lys25Ile (Ensembl:YOR188W_mRNA) - c.74A>T (Ensembl:YOR188W_mRNA) Source type: large scale study Cross-references: - SGRP: s15-685841 | |||||||
s15-685876 | 37 | N>H | SGRP | ||||
Consequence: missense Predictions: - SIFT: deleterious - low confidence (0.01) Somatic: No Accession: XV:g.685875A>C Codon: AAT/CAT Consequence type: missense Cytogenetic band: Genomic location: XV:g.685875A>C Locations: - p.Asn37His (Ensembl:YOR188W_mRNA) - c.109A>C (Ensembl:YOR188W_mRNA) Source type: large scale study Cross-references: - SGRP: s15-685876 | |||||||
s15-685970 | 68 | Q>R | SGRP | ||||
Consequence: missense Predictions: - SIFT: deleterious - low confidence (0.03) Somatic: No Accession: XV:g.685969A>G Codon: CAA/CGA Consequence type: missense Cytogenetic band: Genomic location: XV:g.685969A>G Locations: - p.Gln68Arg (Ensembl:YOR188W_mRNA) - c.203A>G (Ensembl:YOR188W_mRNA) Source type: large scale study Cross-references: - SGRP: s15-685970 | |||||||
s15-686435 | 223 | K>R | SGRP | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.26) Somatic: No Accession: XV:g.686434A>G Codon: AAG/AGG Consequence type: missense Cytogenetic band: Genomic location: XV:g.686434A>G Locations: - p.Lys223Arg (Ensembl:YOR188W_mRNA) - c.668A>G (Ensembl:YOR188W_mRNA) Source type: large scale study Cross-references: - SGRP: s15-686435 | |||||||
s15-686729 | 321 | T>I | SGRP | ||||
Consequence: missense Predictions: - SIFT: deleterious (0) Somatic: No Accession: XV:g.686728C>T Codon: ACC/ATC Consequence type: missense Cytogenetic band: Genomic location: XV:g.686728C>T Locations: - p.Thr321Ile (Ensembl:YOR188W_mRNA) - c.962C>T (Ensembl:YOR188W_mRNA) Source type: large scale study Cross-references: - SGRP: s15-686729 | |||||||
s15-686873 | 369 | R>I | SGRP | ||||
Consequence: missense Predictions: - SIFT: deleterious (0) Somatic: No Accession: XV:g.686872G>T Codon: AGA/ATA Consequence type: missense Cytogenetic band: Genomic location: XV:g.686872G>T Locations: - p.Arg369Ile (Ensembl:YOR188W_mRNA) - c.1106G>T (Ensembl:YOR188W_mRNA) Source type: large scale study Cross-references: - SGRP: s15-686873 | |||||||
s15-686986 | 407 | E>K | SGRP | ||||
Consequence: missense Predictions: - SIFT: tolerated (1) Somatic: No Accession: XV:g.686985G>A Codon: GAA/AAA Consequence type: missense Cytogenetic band: Genomic location: XV:g.686985G>A Locations: - p.Glu407Lys (Ensembl:YOR188W_mRNA) - c.1219G>A (Ensembl:YOR188W_mRNA) Source type: large scale study Cross-references: - SGRP: s15-686986 | |||||||
s15-687086 | 440 | F>S | SGRP | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.38) Somatic: No Accession: XV:g.687085T>C Codon: TTC/TCC Consequence type: missense Cytogenetic band: Genomic location: XV:g.687085T>C Locations: - p.Phe440Ser (Ensembl:YOR188W_mRNA) - c.1319T>C (Ensembl:YOR188W_mRNA) Source type: large scale study Cross-references: - SGRP: s15-687086 | |||||||
s15-687346 | 527 | E>K | SGRP | ||||
Consequence: missense Predictions: - SIFT: tolerated - low confidence (0.06) Somatic: No Accession: XV:g.687345G>A Codon: GAG/AAG Consequence type: missense Cytogenetic band: Genomic location: XV:g.687345G>A Locations: - p.Glu527Lys (Ensembl:YOR188W_mRNA) - c.1579G>A (Ensembl:YOR188W_mRNA) Source type: large scale study Cross-references: - SGRP: s15-687346 | |||||||
s15-687594 | 609 | N>K | SGRP | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.36) Somatic: No Accession: XV:g.687593C>A Codon: AAC/AAA Consequence type: missense Cytogenetic band: Genomic location: XV:g.687593C>A Locations: - p.Asn609Lys (Ensembl:YOR188W_mRNA) - c.1827C>A (Ensembl:YOR188W_mRNA) Source type: large scale study Cross-references: - SGRP: s15-687594 | |||||||
s15-687607 | 614 | S>A | SGRP | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.06) Somatic: No Accession: XV:g.687606T>G Codon: TCG/GCG Consequence type: missense Cytogenetic band: Genomic location: XV:g.687606T>G Locations: - p.Ser614Ala (Ensembl:YOR188W_mRNA) - c.1840T>G (Ensembl:YOR188W_mRNA) Source type: large scale study Cross-references: - SGRP: s15-687607 | |||||||
s15-687740 | 658 | D>G | SGRP | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.09) Somatic: No Accession: XV:g.687739A>G Codon: GAC/GGC Consequence type: missense Cytogenetic band: Genomic location: XV:g.687739A>G Locations: - p.Asp658Gly (Ensembl:YOR188W_mRNA) - c.1973A>G (Ensembl:YOR188W_mRNA) Source type: large scale study Cross-references: - SGRP: s15-687740 | |||||||
s15-687754 | 663 | L>V | SGRP | ||||
Consequence: missense Predictions: - SIFT: tolerated (0.57) Somatic: No Accession: XV:g.687753C>G Codon: CTT/GTT Consequence type: missense Cytogenetic band: Genomic location: XV:g.687753C>G Locations: - p.Leu663Val (Ensembl:YOR188W_mRNA) - c.1987C>G (Ensembl:YOR188W_mRNA) Source type: large scale study Cross-references: - SGRP: s15-687754 | |||||||
s15-688018 | 751 | A>S | SGRP | ||||
Consequence: missense Predictions: - SIFT: tolerated - low confidence (1) Somatic: No Accession: XV:g.688017G>T Codon: GCT/TCT Consequence type: missense Cytogenetic band: Genomic location: XV:g.688017G>T Locations: - p.Ala751Ser (Ensembl:YOR188W_mRNA) - c.2251G>T (Ensembl:YOR188W_mRNA) Source type: large scale study Cross-references: - SGRP: s15-688018 | |||||||
s15-688034 | 756 | A>V | SGRP | ||||
Consequence: missense Predictions: - SIFT: tolerated - low confidence (1) Somatic: No Accession: XV:g.688033C>T Codon: GCG/GTG Consequence type: missense Cytogenetic band: Genomic location: XV:g.688033C>T Locations: - p.Ala756Val (Ensembl:YOR188W_mRNA) - c.2267C>T (Ensembl:YOR188W_mRNA) Source type: large scale study Cross-references: - SGRP: s15-688034 | |||||||
s15-688169 | 801 | A>V | SGRP | ||||
Consequence: missense Predictions: - SIFT: tolerated - low confidence (1) Somatic: No Accession: XV:g.688168C>T Codon: GCA/GTA Consequence type: missense Cytogenetic band: Genomic location: XV:g.688168C>T Locations: - p.Ala801Val (Ensembl:YOR188W_mRNA) - c.2402C>T (Ensembl:YOR188W_mRNA) Source type: large scale study Cross-references: - SGRP: s15-688169 | |||||||
s15-688247 | 827 | K>R | SGRP | ||||
Consequence: missense Predictions: - SIFT: tolerated - low confidence (0.67) Somatic: No Accession: XV:g.688246A>G Codon: AAA/AGA Consequence type: missense Cytogenetic band: Genomic location: XV:g.688246A>G Locations: - p.Lys827Arg (Ensembl:YOR188W_mRNA) - c.2480A>G (Ensembl:YOR188W_mRNA) Source type: large scale study Cross-references: - SGRP: s15-688247 | |||||||
s15-688415 | 883 | N>T | SGRP | ||||
Consequence: missense Predictions: - SIFT: tolerated - low confidence (0.38) Somatic: No Accession: XV:g.688414A>C Codon: AAT/ACT Consequence type: missense Cytogenetic band: Genomic location: XV:g.688414A>C Locations: - p.Asn883Thr (Ensembl:YOR188W_mRNA) - c.2648A>C (Ensembl:YOR188W_mRNA) Source type: large scale study Cross-references: - SGRP: s15-688415 | |||||||
s15-688426 | 887 | G>R | SGRP | ||||
Consequence: missense Predictions: - SIFT: deleterious - low confidence (0) Somatic: No Accession: XV:g.688425G>A Codon: GGG/AGG Consequence type: missense Cytogenetic band: Genomic location: XV:g.688425G>A Locations: - p.Gly887Arg (Ensembl:YOR188W_mRNA) - c.2659G>A (Ensembl:YOR188W_mRNA) Source type: large scale study Cross-references: - SGRP: s15-688426 | |||||||
s15-688434 | 889 | N>K | SGRP | ||||
Consequence: missense Predictions: - SIFT: tolerated - low confidence (1) Somatic: No Accession: XV:g.688433T>A Codon: AAT/AAA Consequence type: missense Cytogenetic band: Genomic location: XV:g.688433T>A Locations: - p.Asn889Lys (Ensembl:YOR188W_mRNA) - c.2667T>A (Ensembl:YOR188W_mRNA) Source type: large scale study Cross-references: - SGRP: s15-688434 | |||||||
s15-688555 | 930 | S>T | SGRP | ||||
Consequence: missense Predictions: - SIFT: tolerated - low confidence (0.18) Somatic: No Accession: XV:g.688554T>A Codon: TCC/ACC Consequence type: missense Cytogenetic band: Genomic location: XV:g.688554T>A Locations: - p.Ser930Thr (Ensembl:YOR188W_mRNA) - c.2788T>A (Ensembl:YOR188W_mRNA) Source type: large scale study Cross-references: - SGRP: s15-688555 | |||||||
s15-688579 | 938 | S>P | SGRP | ||||
Consequence: missense Predictions: - SIFT: tolerated - low confidence (0.18) Somatic: No Accession: XV:g.688578T>C Codon: TCA/CCA Consequence type: missense Cytogenetic band: Genomic location: XV:g.688578T>C Locations: - p.Ser938Pro (Ensembl:YOR188W_mRNA) - c.2812T>C (Ensembl:YOR188W_mRNA) Source type: large scale study Cross-references: - SGRP: s15-688579 | |||||||
s15-688624 | 953 | N>H | SGRP | ||||
Consequence: missense Predictions: - SIFT: tolerated - low confidence (0.39) Somatic: No Accession: XV:g.688623A>C Codon: AAT/CAT Consequence type: missense Cytogenetic band: Genomic location: XV:g.688623A>C Locations: - p.Asn953His (Ensembl:YOR188W_mRNA) - c.2857A>C (Ensembl:YOR188W_mRNA) Source type: large scale study Cross-references: - SGRP: s15-688624 | |||||||
s15-688715 | 983 | P>Q | SGRP | ||||
Consequence: missense Predictions: - SIFT: tolerated - low confidence (0.09) Somatic: No Accession: XV:g.688714C>A Codon: CCG/CAG Consequence type: missense Cytogenetic band: Genomic location: XV:g.688714C>A Locations: - p.Pro983Gln (Ensembl:YOR188W_mRNA) - c.2948C>A (Ensembl:YOR188W_mRNA) Source type: large scale study Cross-references: - SGRP: s15-688715 | |||||||
s15-688720 | 985 | Y>H | SGRP | ||||
Consequence: missense Predictions: - SIFT: tolerated - low confidence (0.53) Somatic: No Accession: XV:g.688719T>C Codon: TAT/CAT Consequence type: missense Cytogenetic band: Genomic location: XV:g.688719T>C Locations: - p.Tyr985His (Ensembl:YOR188W_mRNA) - c.2953T>C (Ensembl:YOR188W_mRNA) Source type: large scale study Cross-references: - SGRP: s15-688720 | |||||||
s15-688732 | 989 | T>S | SGRP | ||||
Consequence: missense Predictions: - SIFT: tolerated - low confidence (0.1) Somatic: No Accession: XV:g.688731A>T Codon: ACA/TCA Consequence type: missense Cytogenetic band: Genomic location: XV:g.688731A>T Locations: - p.Thr989Ser (Ensembl:YOR188W_mRNA) - c.2965A>T (Ensembl:YOR188W_mRNA) Source type: large scale study Cross-references: - SGRP: s15-688732 | |||||||
s15-688812 | 1015 | M>I | SGRP | ||||
Consequence: missense Predictions: - SIFT: deleterious - low confidence (0.02) Somatic: No Accession: XV:g.688811G>A Codon: ATG/ATA Consequence type: missense Cytogenetic band: Genomic location: XV:g.688811G>A Locations: - p.Met1015Ile (Ensembl:YOR188W_mRNA) - c.3045G>A (Ensembl:YOR188W_mRNA) Source type: large scale study Cross-references: - SGRP: s15-688812 | |||||||
s15-688919 | 1051 | P>R | SGRP | ||||
Consequence: missense Predictions: - SIFT: deleterious - low confidence (0) Somatic: No Accession: XV:g.688918C>G Codon: CCT/CGT Consequence type: missense Cytogenetic band: Genomic location: XV:g.688918C>G Locations: - p.Pro1051Arg (Ensembl:YOR188W_mRNA) - c.3152C>G (Ensembl:YOR188W_mRNA) Source type: large scale study Cross-references: - SGRP: s15-688919 | |||||||
s15-689012 | 1082 | G>D | SGRP | ||||
Consequence: missense Predictions: - SIFT: tolerated - low confidence (0.65) Somatic: No Accession: XV:g.689011G>A Codon: GGC/GAC Consequence type: missense Cytogenetic band: Genomic location: XV:g.689011G>A Locations: - p.Gly1082Asp (Ensembl:YOR188W_mRNA) - c.3245G>A (Ensembl:YOR188W_mRNA) Source type: large scale study Cross-references: - SGRP: s15-689012 | |||||||
s15-689066 | 1100 | S>N | SGRP | ||||
Consequence: missense Predictions: - SIFT: deleterious - low confidence (0.01) Somatic: No Accession: XV:g.689065G>A Codon: AGT/AAT Consequence type: missense Cytogenetic band: Genomic location: XV:g.689065G>A Locations: - p.Ser1100Asn (Ensembl:YOR188W_mRNA) - c.3299G>A (Ensembl:YOR188W_mRNA) Source type: large scale study Cross-references: - SGRP: s15-689066 | |||||||
s15-689102 | 1112 | K>R | SGRP | ||||
Consequence: missense Predictions: - SIFT: tolerated - low confidence (0.46) Somatic: No Accession: XV:g.689101A>G Codon: AAA/AGA Consequence type: missense Cytogenetic band: Genomic location: XV:g.689101A>G Locations: - p.Lys1112Arg (Ensembl:YOR188W_mRNA) - c.3335A>G (Ensembl:YOR188W_mRNA) Source type: large scale study Cross-references: - SGRP: s15-689102 |