G protein gamma (Ggamma) subtype dependent targeting of GRK2 to M3 receptor by Gbetagamma.
- AnnotationM3R activation-induced GRK2 recruitment is Ggamma subtype dependent in which Gbetagamma dimers with low cell membrane-affinity Ggamma9 exhibited a two-fold higher GRK2-recruitment compared to high affinity Ggamma3 expressing cells.
- CategoriesFunction, Interaction, Subcellular Location
- SourceGeneRif: 1131