P19920 · DCMM_AFIC5
- ProteinCarbon monoxide dehydrogenase medium chain
- GenecoxM
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids288 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score3/5
Function
function
Catalyzes the oxidation of carbon monoxide to carbon dioxide.
Catalytic activity
- a quinone + CO + H2O = a quinol + CO2
Cofactor
Note: Binds 1 FAD per subunit.
Kinetics
KM | SUBSTRATE | pH | TEMPERATURE[C] | NOTES | EVIDENCE | |
---|---|---|---|---|---|---|
16.4 μM | 1,4-benzoquinone |
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | carbon-monoxide oxygenase activity | |
Molecular Function | FAD binding |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameCarbon monoxide dehydrogenase medium chain
- EC number
- Short namesCO dehydrogenase subunit M; CO-DH M
Gene names
Encoded on
- Plasmid megaplasmid pHCG3
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Alphaproteobacteria > Hyphomicrobiales > Nitrobacteraceae > Afipia
Accessions
- Primary accessionP19920
- Secondary accessions
Proteomes
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000079813 | 1-288 | Carbon monoxide dehydrogenase medium chain | |||
Sequence: MIPGSFDYHRPKSIADAVALLTKLGEDARPLAGGHSLIPIMKTRLATPEHLVDLRDIGDLVGIREEGTDVVIGAMTTQHALIGSDFLAAKLPIIRETSLLIADPQIRYMGTIGGNAANGDPGNDMPALMQCLGAAYELTGPEGARIVAARDYYQGAYFTAIEPGELLTAIRIPVPPTGHGYAYEKLKRKIGDYATAAAAVVLTMSGGKCVTASIGLTNVANTPLWAEEAGKVLVGTALDKPALDKAVALAEAITAPASDGRGPAEYRTKMAGVMLRRAVERAKARAKN |
Interaction
Subunit
Dimer of heterotrimers. Each heterotrimer consists of a large, a medium and a small subunit.
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 1-177 | FAD-binding PCMH-type | ||||
Sequence: MIPGSFDYHRPKSIADAVALLTKLGEDARPLAGGHSLIPIMKTRLATPEHLVDLRDIGDLVGIREEGTDVVIGAMTTQHALIGSDFLAAKLPIIRETSLLIADPQIRYMGTIGGNAANGDPGNDMPALMQCLGAAYELTGPEGARIVAARDYYQGAYFTAIEPGELLTAIRIPVPPT |
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length288
- Mass (Da)30,241
- Last updated2002-07-11 v2
- ChecksumE3EA980056731FC5
Features
Showing features for sequence conflict.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Sequence conflict | 1 | in Ref. 5; AA sequence | ||||
Sequence: M → MM |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP002827 EMBL· GenBank· DDBJ | AEI08104.1 EMBL· GenBank· DDBJ | Genomic DNA |