P19223 · CBPB1_RAT

Function

Catalytic activity

  • Preferential release of a C-terminal lysine or arginine amino acid.
    EC:3.4.17.2 (UniProtKB | ENZYME | Rhea)

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 1 zinc ion per subunit.

Features

Showing features for binding site, active site.

141550100150200250300350400
TypeIDPosition(s)Description
Binding site174Zn2+ (UniProtKB | ChEBI); catalytic
Binding site174-177substrate
Binding site177Zn2+ (UniProtKB | ChEBI); catalytic
Binding site232substrate
Binding site249-250substrate
Binding site302Zn2+ (UniProtKB | ChEBI); catalytic
Binding site303-304substrate
Binding site354substrate
Active site376Proton donor/acceptor

GO annotations

AspectTerm
Cellular Componentcytoplasmic vesicle
Cellular Componentextracellular space
Molecular Functioncarboxypeptidase activity
Molecular Functionmetallocarboxypeptidase activity
Molecular Functionzinc ion binding
Biological Processproteolysis

Keywords

Enzyme and pathway databases

Protein family/group databases

Names & Taxonomy

Protein names

  • Recommended name
    Carboxypeptidase B
  • EC number

Gene names

    • Name
      Cpb1
    • Synonyms
      Cpb

Organism names

  • Taxonomic identifier
  • Strain
    • Wistar
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Rattus

Accessions

  • Primary accession
    P19223

Proteomes

Organism-specific databases

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for signal, propeptide, chain, disulfide bond.

TypeIDPosition(s)Description
Signal1-13
PropeptidePRO_000000437514-108Activation peptide
ChainPRO_0000004376109-415Carboxypeptidase B
Disulfide bond171↔184
Disulfide bond243↔266
Disulfide bond257↔271

Keywords

Proteomic databases

PTM databases

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain116-410Peptidase M14

Sequence similarities

Belongs to the peptidase M14 family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    415
  • Mass (Da)
    47,515
  • Last updated
    1990-11-01 v1
  • Checksum
    8EA06CCADE30B6F2
MLLLLALVSVALAHASEEHFDGNRVYRVSVHGEDHVNLIQELANTKEIDFWKPDSATQVKPLTTVDFHVKAEDVADVENFLEENEVHYEVLISNVRNALESQFDSHTRASGHSYTKYNKWETIEAWIQQVATDNPDLVTQSVIGTTFEGRNMYVLKIGKTRPNKPAIFIDCGFHAREWISPAFCQWFVREAVRTYNQEIHMKQLLDELDFYVLPVVNIDGYVYTWTKDRMWRKTRSTMAGSSCLGVRPNRNFNAGWCEVGASRSPCSETYCGPAPESEKETKALADFIRNNLSTIKAYLTIHSYSQMMLYPYSYDYKLPENYEELNALVKGAAKELATLHGTKYTYGPGATTIYPAAGGSDDWSYDQGIKYSFTFELRDTGFFGFLLPESQIRQTCEETMLAVKYIANYVREHLY

Computationally mapped potential isoform sequences

There is 1 potential isoform mapped to this entry

View all
EntryEntry nameGene nameLength
D3ZAM3D3ZAM3_RATCpb1415

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
M23959
EMBL· GenBank· DDBJ
AAA40872.1
EMBL· GenBank· DDBJ
Genomic DNA
M23947
EMBL· GenBank· DDBJ
AAA40872.1
EMBL· GenBank· DDBJ
Genomic DNA
M23950
EMBL· GenBank· DDBJ
AAA40872.1
EMBL· GenBank· DDBJ
Genomic DNA
M23952
EMBL· GenBank· DDBJ
AAA40872.1
EMBL· GenBank· DDBJ
Genomic DNA
M23953
EMBL· GenBank· DDBJ
AAA40872.1
EMBL· GenBank· DDBJ
Genomic DNA
M23954
EMBL· GenBank· DDBJ
AAA40872.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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