P19171 · CHIB_ARATH
- ProteinBasic endochitinase B
- GeneCHI-B
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids335 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score5/5
Function
function
Defense against chitin-containing fungal pathogens. Seems particularly implicated in resistance to jasmonate-inducing pathogens such as A.brassicicola. In vitro antifungal activity against T.reesei, but not against A.solani, F.oxysporum, S.sclerotiorum, G.graminis and P.megasperma.
Catalytic activity
Features
Showing features for active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 151 | Proton donor | |||
GO annotations
all annotations | all molecular function | nucleotide binding | molecular_function | nucleic acid binding | dna binding | chromatin binding | dna-binding transcription factor activity | rna binding | cytoskeletal motor activity | catalytic activity | nuclease activity | signaling receptor binding | structural molecule activity | transporter activity | binding | protein binding | translation factor activity, rna binding | lipid binding | kinase activity | transferase activity | hydrolase activity | oxygen binding | enzyme regulator activity | carbohydrate binding | signaling receptor activity | translation regulator activity | transcription regulator activity | other molecular function | all biological process | carbohydrate metabolic process | generation of precursor metabolites and energy | nucleobase-containing compound metabolic process | dna metabolic process | translation | lipid metabolic process | transport | response to stress | cell cycle | cell communication | signal transduction | cell-cell signaling | multicellular organism development | circadian rhythm | biological_process | metabolic process | catabolic process | biosynthetic process | response to light stimulus | response to external stimulus | tropism | response to biotic stimulus | response to abiotic stimulus | response to endogenous stimulus | embryo development | post-embryonic development | fruit ripening | abscission | pollination | flower development | cellular process | programmed cell death | photosynthesis | cellular component organization | cell growth | protein metabolic process | cellular homeostasis | secondary metabolic process | reproductive process | cell differentiation | protein modification process | growth | epigenetic regulation of gene expression | response to chemical | anatomical structure development | regulation of molecular function | other biological process | all cellular component | cellular_component | extracellular region | cell wall | intracellular anatomical structure | nucleus | nuclear envelope | nucleoplasm | nucleolus | cytoplasm | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | cytosol | ribosome | cytoskeleton | plasma membrane | chloroplast | plastid | thylakoid | membrane | external encapsulating structure | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | plant-type vacuole | |
Cellular Component | secretory vesicle | |
Cellular Component | vacuole | |
Molecular Function | chitin binding | |
Molecular Function | chitinase activity | |
Biological Process | cell wall macromolecule catabolic process | |
Biological Process | chitin catabolic process | |
Biological Process | defense response to fungus | |
Biological Process | killing of cells of another organism | |
Biological Process | plant-type hypersensitive response | |
Biological Process | polysaccharide catabolic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Protein family/group databases
Names & Taxonomy
Protein names
- Recommended nameBasic endochitinase B
- EC number
- Alternative names
Gene names
Organism names
- Strains
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis
Accessions
- Primary accessionP19171
- Secondary accessions
Proteomes
Organism-specific databases
Genome annotation databases
Subcellular Location
Phenotypes & Variants
Features
Showing features for natural variant.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Natural variant | 17 | in strain: cv. Bl-1, cv. Shokei and cv. Yo-0 | |||
Natural variant | 106 | in strain: cv. Aa-0 | |||
Natural variant | 127 | in strain: cv. Yo-0 | |||
Natural variant | 206 | in strain: cv. Ci-0 | |||
Variants
We now provide the "Disease & Variants" viewer in its own tab.
The viewer provides 29 variants from UniProt as well as other sources including ClinVar and dbSNP.
PTM/Processing
Features
Showing features for signal, chain, disulfide bond, propeptide.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Signal | 1-33 | ||||
Chain | PRO_0000005287 | 34-328 | Basic endochitinase B | ||
Disulfide bond | 36↔51 | ||||
Disulfide bond | 45↔57 | ||||
Disulfide bond | 50↔64 | ||||
Disulfide bond | 69↔73 | ||||
Disulfide bond | 107↔169 | ||||
Disulfide bond | 181↔189 | ||||
Disulfide bond | 288↔320 | ||||
Propeptide | PRO_0000005288 | 329-335 | Removed in mature form | ||
Keywords
- PTM
Proteomic databases
Expression
Tissue specificity
High constitutive level in roots with lower levels in leaves and flowering shoots.
Induction
Ethylene induces high levels of systemic expression of basic chitinase with expression increasing with plant age. Locally and systemically induced by jasmonic acid (JA) and pathogens such as A.brassicicola and P.syringae, particularly in case of hypersensitive responses (HR). Not induced by wounding.
Gene expression databases
Structure
Family & Domains
Features
Showing features for domain, motif.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 34-75 | Chitin-binding type-1 | |||
Motif | 329-335 | Vacuolar targeting signal | |||
Sequence similarities
Belongs to the glycosyl hydrolase 19 family. Chitinase class I subfamily.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Sequence processingThe displayed sequence is further processed into a mature form.
- Length335
- Mass (Da)36,184
- Last updated2005-08-30 v3
- Checksum0973CE89B30ABF61
Sequence caution
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
M38240 EMBL· GenBank· DDBJ | AAA32769.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AB023448 EMBL· GenBank· DDBJ | BAA82810.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AB023449 EMBL· GenBank· DDBJ | BAA82811.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AB023450 EMBL· GenBank· DDBJ | BAA82812.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AB023451 EMBL· GenBank· DDBJ | BAA82813.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AB023452 EMBL· GenBank· DDBJ | BAA82814.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AB023453 EMBL· GenBank· DDBJ | BAA82815.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AB023454 EMBL· GenBank· DDBJ | BAA82816.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AB023455 EMBL· GenBank· DDBJ | BAA82817.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AB023456 EMBL· GenBank· DDBJ | BAA82818.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AB023457 EMBL· GenBank· DDBJ | BAA82819.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AB023458 EMBL· GenBank· DDBJ | BAA82820.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AB023459 EMBL· GenBank· DDBJ | BAA82821.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AB023460 EMBL· GenBank· DDBJ | BAA82822.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AB023461 EMBL· GenBank· DDBJ | BAA82823.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AB023462 EMBL· GenBank· DDBJ | BAA82824.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AB023463 EMBL· GenBank· DDBJ | BAA82825.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AP002047 EMBL· GenBank· DDBJ | BAB03157.1 EMBL· GenBank· DDBJ | Genomic DNA | Different initiation | |
AC069474 EMBL· GenBank· DDBJ | AAG51023.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CP002686 EMBL· GenBank· DDBJ | AEE75203.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AY054628 EMBL· GenBank· DDBJ | AAK96819.1 EMBL· GenBank· DDBJ | mRNA | Different initiation | |
AY081519 EMBL· GenBank· DDBJ | AAM10081.1 EMBL· GenBank· DDBJ | mRNA |