P19171 · CHIB_ARATH

Function

function

Defense against chitin-containing fungal pathogens. Seems particularly implicated in resistance to jasmonate-inducing pathogens such as A.brassicicola. In vitro antifungal activity against T.reesei, but not against A.solani, F.oxysporum, S.sclerotiorum, G.graminis and P.megasperma.

Catalytic activity

  • Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta-linkages in chitin and chitodextrins.
    EC:3.2.1.14 (UniProtKB | ENZYME | Rhea)

Features

Showing features for active site.

133550100150200250300
TypeIDPosition(s)Description
Active site151Proton donor

GO annotations

all annotationsall molecular functionnucleotide bindingmolecular_functionnucleic acid bindingdna bindingchromatin bindingdna-binding transcription factor activityrna bindingcytoskeletal motor activitycatalytic activitynuclease activitysignaling receptor bindingstructural molecule activitytransporter activitybindingprotein bindingtranslation factor activity, rna bindinglipid bindingkinase activitytransferase activityhydrolase activityoxygen bindingenzyme regulator activitycarbohydrate bindingsignaling receptor activitytranslation regulator activitytranscription regulator activityother molecular functionall biological processcarbohydrate metabolic processgeneration of precursor metabolites and energynucleobase-containing compound metabolic processdna metabolic processtranslationlipid metabolic processtransportresponse to stresscell cyclecell communicationsignal transductioncell-cell signalingmulticellular organism developmentcircadian rhythmbiological_processmetabolic processcatabolic processbiosynthetic processresponse to light stimulusresponse to external stimulustropismresponse to biotic stimulusresponse to abiotic stimulusresponse to endogenous stimulusembryo developmentpost-embryonic developmentfruit ripeningabscissionpollinationflower developmentcellular processprogrammed cell deathphotosynthesiscellular component organizationcell growthprotein metabolic processcellular homeostasissecondary metabolic processreproductive processcell differentiationprotein modification processgrowthepigenetic regulation of gene expressionresponse to chemicalanatomical structure developmentregulation of molecular functionother biological processall cellular componentcellular_componentextracellular regioncell wallintracellular anatomical structurenucleusnuclear envelopenucleoplasmnucleoluscytoplasmmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuscytosolribosomecytoskeletonplasma membranechloroplastplastidthylakoidmembraneexternal encapsulating structureother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentplant-type vacuole
Cellular Componentsecretory vesicle
Cellular Componentvacuole
Molecular Functionchitin binding
Molecular Functionchitinase activity
Biological Processcell wall macromolecule catabolic process
Biological Processchitin catabolic process
Biological Processdefense response to fungus
Biological Processkilling of cells of another organism
Biological Processplant-type hypersensitive response
Biological Processpolysaccharide catabolic process

Keywords

Enzyme and pathway databases

Protein family/group databases

    • CBM18Carbohydrate-Binding Module Family 18
    • GH19Glycoside Hydrolase Family 19

Names & Taxonomy

Protein names

  • Recommended name
    Basic endochitinase B
  • EC number
  • Alternative names
    • Pathogenesis-related protein 3 (AtChiB; PR-3)

Gene names

    • Name
      CHI-B
    • Synonyms
      PR3
    • ORF names
      MQC3.32, T2E22.18, T2E22_119
    • Ordered locus names
      At3g12500

Organism names

  • Taxonomic identifier
  • Strains
    • cv. Columbia
    • cv. Aa-0
    • cv. Al-0
    • cv. Bl-1
    • cv. Bla-10
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis

Accessions

  • Primary accession
    P19171
  • Secondary accessions
    • Q9S7J5
    • Q9S838
    • Q9SXJ2
    • Q9SXJ3
    • Q9SXJ4

Proteomes

Organism-specific databases

Genome annotation databases

Subcellular Location

Keywords

Phenotypes & Variants

Features

Showing features for natural variant.

TypeIDPosition(s)Description
Natural variant17in strain: cv. Bl-1, cv. Shokei and cv. Yo-0
Natural variant106in strain: cv. Aa-0
Natural variant127in strain: cv. Yo-0
Natural variant206in strain: cv. Ci-0

Variants

We now provide the "Disease & Variants" viewer in its own tab.

The viewer provides 29 variants from UniProt as well as other sources including ClinVar and dbSNP.

Go to variant viewer

PTM/Processing

Features

Showing features for signal, chain, disulfide bond, propeptide.

Type
IDPosition(s)Description
Signal1-33
ChainPRO_000000528734-328Basic endochitinase B
Disulfide bond36↔51
Disulfide bond45↔57
Disulfide bond50↔64
Disulfide bond69↔73
Disulfide bond107↔169
Disulfide bond181↔189
Disulfide bond288↔320
PropeptidePRO_0000005288329-335Removed in mature form

Keywords

Proteomic databases

Expression

Tissue specificity

High constitutive level in roots with lower levels in leaves and flowering shoots.

Induction

Ethylene induces high levels of systemic expression of basic chitinase with expression increasing with plant age. Locally and systemically induced by jasmonic acid (JA) and pathogens such as A.brassicicola and P.syringae, particularly in case of hypersensitive responses (HR). Not induced by wounding.

Gene expression databases

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for domain, motif.

Type
IDPosition(s)Description
Domain34-75Chitin-binding type-1
Motif329-335Vacuolar targeting signal

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    335
  • Mass (Da)
    36,184
  • Last updated
    2005-08-30 v3
  • Checksum
    0973CE89B30ABF61
MPPQKENHRTLNKMKTNLFLFLIFSLLLSLSSAEQCGRQAGGALCPNGLCCSEFGWCGNTEPYCKQPGCQSQCTPGGTPPGPTGDLSGIISSSQFDDMLKHRNDAACPARGFYTYNAFITAAKSFPGFGTTGDTATRKKEVAAFFGQTSHETTGGWATAPDGPYSWGYCFKQEQNPASDYCEPSATWPCASGKRYYGRGPMQLSWNYNYGLCGRAIGVDLLNNPDLVANDAVIAFKAAIWFWMTAQPPKPSCHAVIAGQWQPSDADRAAGRLPGYGVITNIINGGLECGRGQDGRVADRIGFYQRYCNIFGVNPGGNLDCYNQRSFVNGLLEAAI

Sequence caution

The sequence AAK96819.1 differs from that shown. Reason: Erroneous initiation Truncated N-terminus.
The sequence BAB03157.1 differs from that shown. Reason: Erroneous initiation Truncated N-terminus.

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
M38240
EMBL· GenBank· DDBJ
AAA32769.1
EMBL· GenBank· DDBJ
Genomic DNA
AB023448
EMBL· GenBank· DDBJ
BAA82810.1
EMBL· GenBank· DDBJ
Genomic DNA
AB023449
EMBL· GenBank· DDBJ
BAA82811.1
EMBL· GenBank· DDBJ
Genomic DNA
AB023450
EMBL· GenBank· DDBJ
BAA82812.1
EMBL· GenBank· DDBJ
Genomic DNA
AB023451
EMBL· GenBank· DDBJ
BAA82813.1
EMBL· GenBank· DDBJ
Genomic DNA
AB023452
EMBL· GenBank· DDBJ
BAA82814.1
EMBL· GenBank· DDBJ
Genomic DNA
AB023453
EMBL· GenBank· DDBJ
BAA82815.1
EMBL· GenBank· DDBJ
Genomic DNA
AB023454
EMBL· GenBank· DDBJ
BAA82816.1
EMBL· GenBank· DDBJ
Genomic DNA
AB023455
EMBL· GenBank· DDBJ
BAA82817.1
EMBL· GenBank· DDBJ
Genomic DNA
AB023456
EMBL· GenBank· DDBJ
BAA82818.1
EMBL· GenBank· DDBJ
Genomic DNA
AB023457
EMBL· GenBank· DDBJ
BAA82819.1
EMBL· GenBank· DDBJ
Genomic DNA
AB023458
EMBL· GenBank· DDBJ
BAA82820.1
EMBL· GenBank· DDBJ
Genomic DNA
AB023459
EMBL· GenBank· DDBJ
BAA82821.1
EMBL· GenBank· DDBJ
Genomic DNA
AB023460
EMBL· GenBank· DDBJ
BAA82822.1
EMBL· GenBank· DDBJ
Genomic DNA
AB023461
EMBL· GenBank· DDBJ
BAA82823.1
EMBL· GenBank· DDBJ
Genomic DNA
AB023462
EMBL· GenBank· DDBJ
BAA82824.1
EMBL· GenBank· DDBJ
Genomic DNA
AB023463
EMBL· GenBank· DDBJ
BAA82825.1
EMBL· GenBank· DDBJ
Genomic DNA
AP002047
EMBL· GenBank· DDBJ
BAB03157.1
EMBL· GenBank· DDBJ
Genomic DNA Different initiation
AC069474
EMBL· GenBank· DDBJ
AAG51023.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002686
EMBL· GenBank· DDBJ
AEE75203.1
EMBL· GenBank· DDBJ
Genomic DNA
AY054628
EMBL· GenBank· DDBJ
AAK96819.1
EMBL· GenBank· DDBJ
mRNA Different initiation
AY081519
EMBL· GenBank· DDBJ
AAM10081.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

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