P16218 · GUNH_ACET2
- ProteinEndoglucanase H
- GenecelH
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids900 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score4/5
Function
function
This enzyme catalyzes the endohydrolysis of 1,4-beta-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.
Catalytic activity
Features
Showing features for active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 131 | Proton donor | |||
Active site | 244 | Nucleophile | |||
Active site | 460 | Proton donor | |||
Active site | 565 | Nucleophile | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cell surface | |
Cellular Component | extracellular region | |
Molecular Function | beta-glucosidase activity | |
Molecular Function | cellulase activity | |
Biological Process | cellulose catabolic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Protein family/group databases
Names & Taxonomy
Protein names
- Recommended nameEndoglucanase H
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Bacillota > Clostridia > Eubacteriales > Oscillospiraceae > Acetivibrio
Accessions
- Primary accessionP16218
- Secondary accessions
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Phenotypes & Variants
Chemistry
PTM/Processing
Features
Showing features for signal, chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Signal | 1-44 | ||||
Chain | PRO_0000007854 | 45-900 | Endoglucanase H | ||
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain, region.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 45-298 | GH26 | |||
Region | 300-630 | Catalytic | |||
Region | 303-326 | Disordered | |||
Domain | 655-900 | CBM11 | |||
Domain | 827-900 | Dockerin | |||
Sequence similarities
In the N-terminal section; belongs to the glycosyl hydrolase 5 (cellulase A) family.
In the C-terminal section; belongs to the glycosyl hydrolase 26 family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Sequence processingThe displayed sequence is further processed into a mature form.
- Length900
- Mass (Da)102,416
- Last updated1990-04-01 v1
- Checksum973AFB1954FC246B
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
M31903 EMBL· GenBank· DDBJ | AAA23225.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CP000568 EMBL· GenBank· DDBJ | ABN52701.1 EMBL· GenBank· DDBJ | Genomic DNA |