Control of O-glycan branch formation. Molecular cloning of human cDNA encoding a novel beta1,6-N-acetylglucosaminyltransferase forming core 2 and core 4.Schwientek T., Nomoto M., Levery S.B., Merkx G., van Kessel A.G., Bennett E.P., Hollingsworth M.A., Clausen H.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-1462068, Reactome: R-HSA-1462154PubMedEurope PMCJ. Biol. Chem. 274:4504-4512 (1999)Cited in1Mapped to18
Molecular cloning and expression of a novel beta-1, 6-N- acetylglucosaminyltransferase that forms core 2, core 4, and I branches.Yeh J.-C., Ong E., Fukuda M.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-1462068, Reactome: R-HSA-1462154, Reactome: R-HSA-1462167, Reactome: R-HSA-1462359PubMedEurope PMCJ. Biol. Chem. 274:3215-3221 (1999)Cited in1Mapped to21
Crystal structure at 1.95 A resolution of the breast tumour-specific antibody SM3 complexed with its peptide epitope reveals novel hypervariable loop recognition.Dokurno P., Bates P.A., Band H.A., Stewart L.M., Lally J.M., Burchell J.M., Taylor-Papadimitriou J., Snary D., Sternberg M.J., Freemont P.S.View abstractCategoriesStructureSourcePDB: 1SM3PubMedEurope PMCJ Mol Biol 284:713-728 (1998)Mapped to3
Molecular cloning of a human cDNA encoding beta-1,4-galactosyltransferase with 37% identity to mammalian UDP-Gal:GlcNAc beta-1,4- galactosyltransferase.Sato T., Furukawa K., Bakker H., van den Eijnden D.H., van Die I.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-1462085, Reactome: R-HSA-1967019PubMedEurope PMCProc. Natl. Acad. Sci. U.S.A. 95:472-477 (1998)Cited in1Mapped to19
Cloning of a human UDP-galactose:2-acetamido-2-deoxy-D-glucose 3beta- galactosyltransferase catalyzing the formation of type 1 chains.Kolbinger F., Streiff M.B., Katopodis A.G.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-1462068, Reactome: R-HSA-913642PubMedEurope PMCJ. Biol. Chem. 273:433-440 (1998)Cited in1Mapped to35
Localization of three human polypeptide GalNAc-transferases in HeLa cells suggests initiation of O-linked glycosylation throughout the Golgi apparatus.Roettger S., White J., Wandall H.H., Olivo J.-C., Stark A., Bennett E.P., Whitehouse C., Berger E.G., Clausen H., Nilsson T.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-913611, Reactome: R-HSA-913642PubMedEurope PMCJ. Cell Sci. 111:45-60 (1998)Cited in3Mapped to35
Substrate specificities of three members of the human UDP-N-acetyl-alpha- D-galactosamine:polypeptide N-acetylgalactosaminyltransferase family, GalNAc-T1, -T2, and -T3.Wandall H.H., Hassan H., Mirgorodskaya E., Kristensen A.K., Roepstorff P., Bennett E.P., Nielsen P.A., Hollingsworth M.A., Burchell J.[...], Clausen H.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-913611, Reactome: R-HSA-913642PubMedEurope PMCJ. Biol. Chem. 272:23503-23514 (1997)Cited in3Mapped to35
Molecular cloning and expression of human Gal beta 1,3GalNAc alpha 2,3- sialyltransferase (hST3Gal II).Kim Y.-J., Kim K.-S., Kim S.-H., Kim C.-H., Ko J.H., Choe I.-S., Tsuji S., Lee Y.-C.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-1462359, Reactome: R-HSA-1463483PubMedEurope PMCBiochem. Biophys. Res. Commun. 228:324-327 (1996)Cited in1Mapped to30
Characterization of two glycolipid: alpha 2-3sialyltransferases, SAT-3 (CMP-NeuAc:nLcOse4Cer alpha 2-3sialyltransferase) and SAT-4 (CMP- NeuAc:GgOse4Cer alpha 2-3sialyltransferase), from human colon carcinoma (Colo 205) cell line.Basu S.S., Basu M., Li Z., Basu S.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-1462359, Reactome: R-HSA-1463483PubMedEurope PMCBiochemistry 35:5166-5174 (1996)Cited in1Mapped to30
Molecular cloning and expression of cDNA encoding human macrophage c-type lectin: its unique carbohydrate binding specificity for Tn antigen.Suzuki N., Yamamoto K., Toyoshima S., Osawa T., Irimura T.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-8858449PubMedEurope PMCJ. Immunol. 156:128-135 (1996)Cited in1Mapped to18
Cloning and expression of human Gal beta 1,3(4)GlcNAc alpha 2,3- sialyltransferase.Kitagawa H., Paulson J.C.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-1462359, Reactome: R-HSA-1463483PubMedEurope PMCBiochem. Biophys. Res. Commun. 194:375-382 (1993)Cited in1Mapped to30
Reverse-engineering the anti-MUC1 antibody 139H2 by mass spectrometry- based de novo sequencing.Peng W., Giesbers K.C., Siborova M., Beugelink J.W., Pronker M.F., Schulte D., Hilkens J., Janssen B.J., Strijbis K., Snijder J.View abstractCategoriesStructureSourcePDB: 8P6IPubMedEurope PMCLife Sci Alliance 7:e202302366-e202302366 (2024)Mapped to1
Structure-Guided Approach for the Development of MUC1-Glycopeptide-Based Cancer Vaccines with Predictable Responses.Bermejo I.A., Guerreiro A., Eguskiza A., Martinez-Saez N., Lazaris F.S., Asin A., Somovilla V.J., Companon I., Raju T.K.[...], Corzana F.View abstractCategoriesStructureSourcePDB: 8AXHPubMedEurope PMCJACS Au 4:150-163 (2024)Mapped to1
Synthesis, conformational analysis and <i>in vivo</i> assays of an anti- cancer vaccine that features an unnatural antigen based on an sp<sup>2</sup>-iminosugar fragment.Bermejo I.A., Navo C.D., Castro-Lopez J., Guerreiro A., Jimenez-Moreno E., Sanchez Fernandez E.M., Garcia-Martin F., Hinou H., Nishimura S.I.[...], Corzana F.View abstractCategoriesStructureSourcePDB: 6TGGPubMedEurope PMCChem Sci 11:3996-4006 (2020)Mapped to1
Mapping the O-glycoproteome using site-specific extraction of O-linked glycopeptides (EXoO).Yang W., Ao M., Hu Y., Li Q.K., Zhang H.View abstractCategoriesPTM / ProcessingSourcePRO: PR:000055512, PRO: PR:000055513, PRO: PR:000055514, PRO: PR:000055515, PRO: PR:000055516, PRO: PR:000055517, PRO: PR:000055518, PRO: PR:000055519, PRO: PR:000055520, PRO: PR:000055521PubMedEurope PMCMol Syst Biol 14:e8486-e8486 (2018)Mapped to99+
Water Sculpts the Distinctive Shapes and Dynamics of the Tumor-Associated Carbohydrate Tn Antigens: Implications for Their Molecular Recognition.Bermejo I.A., Usabiaga I., Companon I., Castro-Lopez J., Insausti A., Fernandez J.A., Avenoza A., Busto J.H., Jimenez-Barbero J.[...], Corzana F.View abstractCategoriesStructureSourcePDB: 6FZQ, PDB: 6FZRPubMedEurope PMCJ Am Chem Soc 140:9952-9960 (2018)Mapped to1
Glycosylation of MUC1 influences the binding of a therapeutic antibody by altering the conformational equilibrium of the antigen.Movahedin M., Brooks T.M., Supekar N.T., Gokanapudi N., Boons G.J., Brooks C.L.View abstractCategoriesStructureSourcePDB: 5T6P, PDB: 5T78PubMedEurope PMCGlycobiology 27:677-687 (2017)Mapped to1
Hyperostosis-hyperphosphatemia syndrome (HHS): report of two cases with a recurrent mutation and review of the literature.Ghafouri-Fard S., Abbasi F., Azizi F., Javaheri M., Mehdizadeh M., Setoodeh A.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-913611PubMedEurope PMCJ Pediatr Endocrinol Metab 28:231-235 (2015)Mapped to19
STAT3 Target Genes Relevant to Human Cancers.Carpenter R.L., Lo H.W.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-6793976PubMedEurope PMCCancers (Basel) 6:897-925 (2014)Mapped to62
The mammalian-membrane two-hybrid assay (MaMTH) for probing membrane- protein interactions in human cells.Petschnigg J., Groisman B., Kotlyar M., Taipale M., Zheng Y., Kurat C.F., Sayad A., Sierra J.R., Mattiazzi Usaj M.[...], Stagljar I.View abstractCategoriesInteractionSourceIntAct: P15941PubMedEurope PMCNat Methods 11:585-592 (2014)Mapped to99+
The Cosmc connection to the Tn antigen in cancer.Ju T., Aryal R.P., Kudelka M.R., Wang Y., Cummings R.D.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-1462359, Reactome: R-HSA-913642PubMedEurope PMCCancer Biomark 14:63-81 (2014)Mapped to20
The B cell antigen CD75 is a cell surface sialyltransferase.Stamenkovic I., Asheim H.C., Deggerdal A., Blomhoff H.K., Smeland E.B., Funderud S.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-1463526, Reactome: R-HSA-913642PubMedEurope PMCJ. Exp. Med. 172:641-643 (1990)Cited in1Mapped to18
Tumor-associated Neu5Ac-Tn and Neu5Gc-Tn antigens bind to C-type lectin CLEC10A (CD301, MGL).Mortezai N., Behnken H.N., Kurze A.K., Ludewig P., Buck F., Meyer B., Wagener C.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-8858449PubMedEurope PMCGlycobiology 23:844-852 (2013)Mapped to19
Cooperative interaction of MUC1 with the HGF/c-Met pathway during hepatocarcinogenesis.Bozkaya G., Korhan P., Cokaklı M., Erdal E., Sagol O., Karademir S., Korch C., Atabey N.View abstractCategoriesInteractionSourceIntAct: P15941PubMedEurope PMCMol Cancer 11:64-64 (2012)Mapped to25
The MUC1 extracellular domain subunit is found in nuclear speckles and associates with spliceosomes.Kumar P., Kumar P., Lindberg L., Thirkill T.L., Ji J.W., Martsching L., Douglas G.C.View abstractCategoriesInteractionSourceIntAct: P15941PubMedEurope PMCPLoS One 7:e42712-e42712 (2012)Mapped to4