P15058 · SPI1_VACCW

Function

function

Plays a role in mediating viral host range. May act to inhibit a caspase independent form of apoptosis to allow efficient virus replication in infected cells.

Features

Showing features for site.

135350100150200250300350
TypeIDPosition(s)Description
Site318-319Reactive bond

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentextracellular space
Cellular Componenthost cell cytoplasm
Molecular Functionserine-type endopeptidase inhibitor activity

Keywords

Protein family/group databases

Names & Taxonomy

Protein names

  • Recommended name
    Serine proteinase inhibitor 1
  • Short names
    Serp-1; Serpin-1

Gene names

    • Name
      OPG205
    • Synonyms
      SPI-1
    • ORF names
      B22R, B24R, C12L
    • Ordered locus names
      VACWR205

Organism names

Accessions

  • Primary accession
    P15058
  • Secondary accessions
    • Q76ZK3

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00000941361-353Serine proteinase inhibitor 1

Expression

Keywords

Structure

3D structure databases

Family & Domains

Sequence similarities

Belongs to the serpin family. Poxviruses subfamily.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    353
  • Mass (Da)
    40,466
  • Last updated
    1990-04-01 v1
  • Checksum
    331A58D188AF34C7
MDIFKELILKHTDENVLISPVSILSTLSILNHGAAGSTAEQLSKYIENMNENTPDDNNDMDVDIPYCATLATANKIYGSDSIEFHASFLQKIKDDFQTVNFNNANQTKELINEWVKTMTNGKINSLLTSPLSINTRMTVVSAVHFKAMWKYPFSKHLTYTDKFYISKNIVTSVDMMVSTENNLQYVHINELFGGFSIIDIPYEGNSSMVIILPDDIEGIYNIEKNITDEKFKKWCGMLSTKSIDLYMPKFKVEMTEPYNLVPILENLGLTNIFGYYADFSKMCNETITVEKFLHTTFIDVNEEYTEASAVTGVFMTNFSMVYRTKVYINHPFMYMIKDNTGRILFIGKYCYPQ

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
D11079
EMBL· GenBank· DDBJ
BAA01852.1
EMBL· GenBank· DDBJ
Genomic DNA
M24217
EMBL· GenBank· DDBJ
AAA48344.1
EMBL· GenBank· DDBJ
Genomic DNA
D00582
EMBL· GenBank· DDBJ
BAA00459.1
EMBL· GenBank· DDBJ
Genomic DNA
M23701
EMBL· GenBank· DDBJ
AAA69589.1
EMBL· GenBank· DDBJ
Genomic DNA
AY243312
EMBL· GenBank· DDBJ
AAO89484.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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