annexin overexpression promoted external blebs enriched in Ca2+ and correlated with a reduction of intracellular Ca2+ at the injury site. Annexin A6 overexpression reduced membrane injury consistent with enhanced repair. Treatment with recombinant annexin A6 protected against acute muscle injury in vitro and in vivo.
AnxA6 contributing to the fine-tuning of hepatic glucose metabolism with potential consequences for the systemic control of glucose in health and disease.
Annexin A6-deficient mice showed increased sensitivity to mechanical stimuli overexpression of annexin A6 in sensory neurons attenuated mechanical pain in a mouse model of osteoarthritis
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