P14742 · GFA1_YEAST

Function

function

Involved in amino sugar synthesis (formation of chitin, supplies the amino sugars of asparagine-linked oligosaccharides of glycoproteins).

Miscellaneous

Present with 14300 molecules/cell in log phase SD medium.

Catalytic activity

Pathway

Nucleotide-sugar biosynthesis; UDP-N-acetyl-alpha-D-glucosamine biosynthesis; alpha-D-glucosamine 6-phosphate from D-fructose 6-phosphate: step 1/1.

Features

Showing features for active site.

TypeIDPosition(s)Description
Active site2For GATase activity

GO annotations

AspectTerm
Molecular Functioncarbohydrate derivative binding
Molecular Functionglutamine-fructose-6-phosphate transaminase (isomerizing) activity
Biological Processchitin biosynthetic process
Biological Processfructose 6-phosphate metabolic process
Biological Processglutamine metabolic process
Biological Processprotein N-linked glycosylation
Biological ProcessUDP-N-acetylglucosamine biosynthetic process
Biological ProcessUDP-N-acetylglucosamine metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Glutamine--fructose-6-phosphate aminotransferase [isomerizing]
  • EC number
  • Short names
    GFAT
  • Alternative names
    • D-fructose-6-phosphate amidotransferase
    • Hexosephosphate aminotransferase

Gene names

    • Name
      GFA1
    • ORF names
      YKL457
    • Ordered locus names
      YKL104C

Organism names

Accessions

  • Primary accession
    P14742
  • Secondary accessions
    • D6VXI4

Proteomes

Organism-specific databases

PTM/Processing

Features

Showing features for initiator methionine, chain, modified residue.

TypeIDPosition(s)Description
Initiator methionine1Removed
ChainPRO_00001352892-717Glutamine--fructose-6-phosphate aminotransferase [isomerizing]
Modified residue253Phosphoserine
Modified residue334Phosphothreonine
Modified residue336Phosphoserine

Keywords

Proteomic databases

PTM databases

Expression

Induction

The activity of this enzyme increases in presence of mating pheromone (transcriptional regulation).

Interaction

Protein-protein interaction databases

Miscellaneous

Structure

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain2-318Glutamine amidotransferase type-2
Domain390-529SIS 1
Domain562-707SIS 2

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    717
  • Mass (Da)
    80,047
  • Last updated
    2007-01-23 v4
  • Checksum
    27E5F0D24BDC451A
MCGIFGYCNYLVERSRGEIIDTLVDGLQRLEYRGYDSTGIAIDGDEADSTFIYKQIGKVSALKEEITKQNPNRDVTFVSHCGIAHTRWATHGRPEQVNCHPQRSDPEDQFVVVHNGIITNFRELKTLLINKGYKFESDTDTECIAKLYLHLYNTNLQNGHDLDFHELTKLVLLELEGSYGLLCKSCHYPNEVIATRKGSPLLIGVKSEKKLKVDFVDVEFPEENAGQPEIPLKSNNKSFGLGPKKAREFEAGSQNANLLPIAANEFNLRHSQSRAFLSEDGSPTPVEFFVSSDAASVVKHTKKVLFLEDDDLAHIYDGELHIHRSRREVGASMTRSIQTLEMELAQIMKGPYDHFMQKEIYEQPESTFNTMRGRIDYENNKVILGGLKAWLPVVRRARRLIMIACGTSYHSCLATRAIFEELSDIPVSVELASDFLDRKCPVFRDDVCVFVSQSGETADTMLALNYCLERGALTVGIVNSVGSSISRVTHCGVHINAGPEIGVASTKAYTSQYIALVMFALSLSDDRVSKIDRRIEIIQGLKLIPGQIKQVLKLEPRIKKLCATELKDQKSLLLLGRGYQFAAALEGALKIKEISYMHSEGVLAGELKHGVLALVDENLPIIAFGTRDSLFPKVVSSIEQVTARKGHPIIICNENDEVWAQKSKSIDLQTLEVPQTVDCLQGLINIIPLQLMSYWLAVNKGIDVDFPRNLAKSVTVE

Features

Showing features for sequence conflict.

TypeIDPosition(s)Description
Sequence conflict453-454in Ref. 1; AAA34643
Sequence conflict534in Ref. 1; AAA34643

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
J04719
EMBL· GenBank· DDBJ
AAA34643.1
EMBL· GenBank· DDBJ
Genomic DNA
X71133
EMBL· GenBank· DDBJ
CAA50453.1
EMBL· GenBank· DDBJ
Genomic DNA
Z28104
EMBL· GenBank· DDBJ
CAA81944.1
EMBL· GenBank· DDBJ
Genomic DNA
BK006944
EMBL· GenBank· DDBJ
DAA09054.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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