glp-1 and lin-12, genes implicated in distinct cell-cell interactions in C. elegans, encode similar transmembrane proteins.Yochem J., Greenwald I.View abstractCited forNUCLEOTIDE SEQUENCE [GENOMIC DNA]StrainBristol N2CategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCCell 58:553-563 (1989)Cited in1
2.2 Mb of contiguous nucleotide sequence from chromosome III of C. elegans.Wilson R., Ainscough R., Anderson K., Baynes C., Berks M., Bonfield J., Burton J., Connell M., Copsey T.[...], Wohldman P.View abstractCited forNUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]StrainBristol N2CategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCNature 368:32-38 (1994)Cited in99+4
Genome sequence of the nematode C. elegans: a platform for investigating biology.The C. elegans sequencing consortiumView abstractCited forNUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]StrainBristol N2CategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCScience 282:2012-2018 (1998)Cited in99+99+
Carboxy-terminal truncation activates glp-1 protein to specify vulval fates in Caenorhabditis elegans.Mango S.E., Maine E.M., Kimble J.View abstractCited forDELETION OF 1174-1295SourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCNature 352:811-815 (1991)Cited in1
Control of cell fate in C. elegans by a GLP-1 peptide consisting primarily of ankyrin repeats.Roehl H., Kimble J.View abstractCited forCHARACTERIZATION OF FUNCTION OF THE ANKYRIN REPEATSCategoriesFunction, Family & DomainsSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCNature 364:632-635 (1993)Cited in1
The maternal genes apx-1 and glp-1 and establishment of dorsal-ventral polarity in the early C. elegans embryo.Mello C.C., Draper B.W., Priess J.R.View abstractCited forFUNCTIONCategoriesFunctionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCCell 77:95-106 (1994)Cited in2Mapped to2
lag-2 may encode a signaling ligand for the GLP-1 and LIN-12 receptors of C. elegans.Henderson S.T., Gao D., Lambie E.J., Kimble J.View abstractCited forFUNCTION, SUBCELLULAR LOCATION, TISSUE SPECIFICITYCategoriesFunction, Expression, Subcellular LocationSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCDevelopment 120:2913-2924 (1994)Cited in2
Facilitation of lin-12-mediated signalling by sel-12, a Caenorhabditis elegans S182 Alzheimer's disease gene.Levitan D., Greenwald I.View abstractCited forFUNCTION, PROTEOLYTIC PROCESSINGCategoriesFunction, PTM / ProcessingSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCNature 377:351-354 (1995)Cited in3
Roles of the RAM and ANK domains in signaling by the C. elegans GLP-1 receptor.Roehl H., Bosenberg M., Blelloch R., Kimble J.View abstractCited forFUNCTION, INTERACTION WITH LAG-1, SUBCELLULAR LOCATIONCategoriesFunction, Interaction, Subcellular LocationSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCEMBO J. 15:7002-7012 (1996)Cited in2
Evidence for functional and physical association between Caenorhabditis elegans SEL-10, a Cdc4p-related protein, and SEL-12 presenilin.Wu G., Hubbard E.J.A., Kitajewski J.K., Greenwald I.View abstractCited forINTERACTION WITH SEL-10CategoriesInteractionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCProc. Natl. Acad. Sci. U.S.A. 95:15787-15791 (1998)Cited in3
SEL-8, a nuclear protein required for LIN-12 and GLP-1 signaling in Caenorhabditis elegans.Doyle T.G., Wen C., Greenwald I.View abstractCited forFUNCTIONCategoriesFunctionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCProc. Natl. Acad. Sci. U.S.A. 97:7877-7881 (2000)Cited in2
Evidence for functional redundancy between C. elegans ADAM proteins SUP- 17/Kuzbanian and ADM-4/TACE.Jarriault S., Greenwald I.View abstractCited forFUNCTION, PROTEOLYTIC PROCESSINGCategoriesFunction, PTM / ProcessingSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCDev. Biol. 287:1-10 (2005)Cited in4
LIP-1 phosphatase controls the extent of germline proliferation in Caenorhabditis elegans.Lee M.H., Hook B., Lamont L.B., Wickens M., Kimble J.View abstractCited forFUNCTION, MUTAGENESIS OF GLY-1043CategoriesFunction, Phenotypes & VariantsSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCEMBO J. 25:88-96 (2006)Cited in6
Notch signalling is required for both dauer maintenance and recovery in C. elegans.Ouellet J., Li S., Roy R.View abstractCited forFUNCTION, SUBCELLULAR LOCATION, DEVELOPMENTAL STAGE, MUTAGENESIS OF ARG-974CategoriesFunction, Expression, Phenotypes & Variants, Subcellular LocationSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCDevelopment 135:2583-2592 (2008)Cited in3Mapped to23
The canonical Notch signaling pathway: unfolding the activation mechanism.Kopan R., Ilagan M.X.View abstractCited forREVIEW OF FUNCTIONCategoriesFunctionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCCell 137:216-233 (2009)Cited in1
MSP and GLP-1/Notch signaling coordinately regulate actomyosin-dependent cytoplasmic streaming and oocyte growth in C. elegans.Nadarajan S., Govindan J.A., McGovern M., Hubbard E.J., Greenstein D.View abstractCited forFUNCTION, DISRUPTION PHENOTYPE, MUTAGENESIS OF ALA-1034CategoriesFunction, Phenotypes & VariantsSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCDevelopment 136:2223-2234 (2009)Cited in3
Autophagy and lipid metabolism coordinately modulate life span in germline-less C. elegans.Lapierre L.R., Gelino S., Melendez A., Hansen M.View abstractCited forFUNCTION, MUTAGENESIS OF ARG-974CategoriesFunction, Phenotypes & VariantsSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCCurr. Biol. 21:1507-1514 (2011)Cited in2Mapped to13
The Ras-ERK MAPK regulatory network controls dedifferentiation in Caenorhabditis elegans germline.Cha D.S., Datla U.S., Hollis S.E., Kimble J., Lee M.H.View abstractCited forMUTAGENESIS OF GLY-1043CategoriesPhenotypes & VariantsSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCBiochim. Biophys. Acta 1823:1847-1855 (2012)Cited in6
S6K links cell fate, cell cycle and nutrient response in C. elegans germline stem/progenitor cells.Korta D.Z., Tuck S., Hubbard E.J.View abstractCited forFUNCTION, DISRUPTION PHENOTYPE, MUTAGENESIS OF GLY-529 AND ARG-974CategoriesFunction, Phenotypes & VariantsSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCDevelopment 139:859-870 (2012)Cited in4
Germline signaling mediates the synergistically prolonged longevity produced by double mutations in daf-2 and rsks-1 in C. elegans.Chen D., Li P.W., Goldstein B.A., Cai W., Thomas E.L., Chen F., Hubbard A.E., Melov S., Kapahi P.View abstractCited forFUNCTION, DISRUPTION PHENOTYPE, MUTAGENESIS OF LEU-929CategoriesFunction, Phenotypes & VariantsSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCCell Rep. 5:1600-1610 (2013)Cited in3
Small nucleoli are a cellular hallmark of longevity.Tiku V., Jain C., Raz Y., Nakamura S., Heestand B., Liu W., Spaeth M., Suchiman H.E.D., Mueller R.U.[...], Antebi A.View abstractCited forFUNCTION, MUTAGENESIS OF ARG-974CategoriesFunction, Phenotypes & VariantsSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCNat. Commun. 8:16083-16083 (2016)Cited in5Mapped to14
GLP-1 Notch-LAG-1 CSL control of the germline stem cell fate is mediated by transcriptional targets lst-1 and sygl-1.Chen J., Mohammad A., Pazdernik N., Huang H., Bowman B., Tycksen E., Schedl T.View abstractCited forFUNCTIONCategoriesFunctionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCPLoS Genet. 16:e1008650-e1008650 (2020)Cited in2Mapped to3
Complexity of developmental control: analysis of embryonic cell lineage specification in Caenorhabditis elegans using pes-1 as an early marker.Molin L., Schnabel H., Kaletta T., Feichtinger R., Hope I.A., Schnabel R.View abstractCategoriesPhenotypes & VariantsSourceWormBase: WBGene00001609PubMedEurope PMCGenetics 151:131-141 (1999)Cited in1Mapped to26
Genetic regulation of entry into meiosis in Caenorhabditis elegans.Kadyk L.C., Kimble J.View abstractCategoriesExpressionSourceWormBase: WBGene00001609PubMedEurope PMCDevelopment 125:1803-1813 (1998)Cited in1Mapped to3
Functional domains of LAG-2, a putative signaling ligand for LIN-12 and GLP-1 receptors in Caenorhabditis elegans.Henderson S.T., Gao D., Christensen S., Kimble J.View abstractCategoriesExpressionSourceWormBase: WBGene00001609, WormBase: WBGene00001609PubMedEurope PMCMol. Biol. Cell 8:1751-1762 (1997)Cited in1Mapped to1