P13375 · G6PI1_GEOSE
- ProteinGlucose-6-phosphate isomerase 1
- Genepgi1
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids449 (go to sequence)
- Protein existenceInferred from homology
- Annotation score4/5
Function
function
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
Catalytic activity
- alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate
Pathway
Carbohydrate biosynthesis; gluconeogenesis.
Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4.
Features
Showing features for active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 290 | Proton donor | |||
Active site | 311 | ||||
Active site | 425 | ||||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | carbohydrate derivative binding | |
Molecular Function | glucose-6-phosphate isomerase activity | |
Molecular Function | monosaccharide binding | |
Biological Process | gluconeogenesis | |
Biological Process | glucose 6-phosphate metabolic process | |
Biological Process | glycolytic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameGlucose-6-phosphate isomerase 1
- EC number
- Short namesGPI 1
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Bacillati > Bacillota > Bacilli > Bacillales > Bacillaceae > Geobacillus
Accessions
- Primary accessionP13375
Subcellular Location
PTM/Processing
Features
Showing features for chain, modified residue.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000180591 | 1-449 | Glucose-6-phosphate isomerase 1 | ||
Modified residue | 38 | Phosphothreonine | |||
Keywords
- PTM
Interaction
Subunit
Homodimer.
Structure
Sequence
- Sequence statusComplete
- Length449
- Mass (Da)50,337
- Last updated1990-01-01 v1
- MD5 ChecksumC8E5B5C7D03D3E9EA84C36E0BC2BB00A
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
X16639 EMBL· GenBank· DDBJ | CAA34634.1 EMBL· GenBank· DDBJ | Genomic DNA |