P13065 · PHSL_DESBA

Function

Miscellaneous

Perhaps the leader of the small subunit serves as a transport vehicle for both subunits.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
Fe cation (UniProtKB | Rhea| CHEBI:24875 )
Note: Binds 2 irons ions. Iron 1 has 3 cyanide and carbon monoxide ligands. Iron 2 has 3 water ligands.
Ni2+ (UniProtKB | Rhea| CHEBI:49786 )
Note: Binds 1 nickel ion per subunit.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site52Fe cation 2 (UniProtKB | ChEBI)
Binding site71Ni2+ (UniProtKB | ChEBI)
Binding site74Fe cation 1 (UniProtKB | ChEBI)
Binding site74Ni2+ (UniProtKB | ChEBI)
Binding site445Fe cation 2 (UniProtKB | ChEBI)
Binding site493Ni2+ (UniProtKB | ChEBI)
Binding site496Fe cation 1 (UniProtKB | ChEBI)
Binding site496Ni2+ (UniProtKB | ChEBI)
Binding site499Fe cation 2 (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentperiplasmic space
Molecular Functionferredoxin hydrogenase activity
Molecular Functionhydrogenase (acceptor) activity
Molecular Functionnickel cation binding

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Periplasmic [NiFeSe] hydrogenase large subunit
  • EC number
  • Alternative names
    • NiFeSe hydrogenlyase large chain

Organism names

Accessions

  • Primary accession
    P13065

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for initiator methionine, chain.

Type
IDPosition(s)Description
Initiator methionine1Removed
ChainPRO_00001997042-514Periplasmic [NiFeSe] hydrogenase large subunit

Interaction

Subunit

Heterodimer of a large and a small subunit.

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    514
  • Mass (Da)
    56,862
  • Last updated
    2008-02-26 v3
  • Checksum
    AC920132081C1ADC
MSQAATPAADGKVKISIDPLTRVEGHLKIEVEVKDGKVVDAKCSGGMFRGFEQILRGRDPRDSSQIVQRICGVCPTAHCTASVMAQDDAFGVKVTTNGRITRNLIFGANYLQSHILHFYHLAALDYVKGPDVSPFVPRYANADLLTDRIKDGAKADATNTYGLNQYLKALEIRRICHEMVAMFGGRMPHVQGMVVGGATEIPTADKVAEYAARFKEVQKFVIEEYLPLIYTLGSVYTDLFETGIGWKNVIAFGVFPEDDDYKTFLLKPGVYIDGKDEEFDSKLVKEYVGHSFFDHSAPGGLHYSVGETNPNPDKPGAYSFVKAPRYKDKPCEVGPLARMWVQNPELSPVGQKLLKELYGIEAKKFRDLGDKAFSIMGRHVLVAEETWLTAVAVEKWLKQVQPGAETYVKSEIPDAAEGTGFTEAPRGALLHYLKIKDKKIENYQIVSATLWNANPRDDMGQRGPIEEALIGVPVPDIKNPVNVGRLVRSYDPULGCAVHVLHAETGEEHVVNID

Features

Showing features for non-standard residue.

TypeIDPosition(s)Description
Non-standard residue493Selenocysteine

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
M18271
EMBL· GenBank· DDBJ
AAA23375.2
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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