P13043 · GVPD1_HALSA

Function

function

Causes a decrease in the amount of GvpE protein (By similarity).
The 5'-region of its promoter or mRNA has a repressive function on downstream genes (PubMed:7651141).
Gas vesicles are hollow, gas filled proteinaceous nanostructures found in several microbial planktonic microorganisms. They allow positioning of halobacteria at the optimal depth for growth in the poorly aerated, shallow brine pools of their habitat (PubMed:33711860).
Expression of a 9.5 kb p-vac DNA fragment containing 2 divergently transcribed regions (gvpD-gvpE-gvpF-gvpG-gvpH-gvpI-gvpJ-gvpK-gvpL-gvpM and gvpA-gvpC-gvpN-gvpO) allows H.volcanii to produce gas vesicles (PubMed:1404376, PubMed:7651141).
A similar region restores gas vesicle production in H.halobium without the p-vac locus, but it still has the c-vac locus (PubMed:1398080, PubMed:8002589).

Miscellaneous

Encoded in a 14-gene plasmid locus called p-vac which produces predominantly short, spindle-shaped gas vesicles during all stages of growth.

Features

Showing features for binding site.

153650100150200250300350400450500
TypeIDPosition(s)Description
Binding site39-46ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Protein GvpD1

Gene names

    • Name
      gvpD11
    • Synonyms
      gvpD
      , p-gvpD
    • Ordered locus names
      VNG_5029G
    • Name
      gvpD1
    • Ordered locus names
      VNG_6028G

Encoded on

  • Plasmid pNRC100
  • Plasmid pNRC200
  • Plasmid pHH1

Organism names

Accessions

  • Primary accession
    P13043
  • Secondary accessions
    • Q9HI19

Proteomes

    • Identifier
    • Component
      Plasmid pNRC100, Plasmid pNRC200

Subcellular Location

Cytoplasm
Note: Probably not part of the mature gas vesicle.

Keywords

Phenotypes & Variants

Disruption phenotype

Partially gas vesicle-deficient (PubMed:1956294, PubMed:2552415, PubMed:8002589).
A double gvpD1-gvpE1 deletion is partially gas vesicle-deficient, still transcribes gvpA1 (PubMed:7651141).

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00001826751-536Protein GvpD1

Expression

Induction

Transcribed divergently from the gvpA gene (PubMed:1864501).
Maximally transcribed in late log phase, probably part of a gvpD1-gvpE1 operon (PubMed:1956294, PubMed:7651141).
Gas vesicles appear earlier when grown in static culture, possibly due to O2-limitation (PubMed:33711860).

Interaction

Subunit

Interacts with GvpE.

Family & Domains

Features

Showing features for region, compositional bias.

TypeIDPosition(s)Description
Region352-413Disordered
Compositional bias366-382Polar residues

Sequence similarities

Belongs to the gas vesicle GvpD family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    536
  • Mass (Da)
    59,342
  • Last updated
    1990-01-01 v1
  • Checksum
    3FC4E4F8F129F9CD
MSSPNLAHPPTDYTGIVLFPRELSQFFMGDAGETLLINGAPGTGKTLFTIRGLDVLDRDSDVLYVSTRVDQETVHEMYFADHSSLDTTAILDLFQDPFELPLDVDVPFEKLDLDSLLEWIQEINAATTQLTIAFDSWELIYEYLAVRHDDPPDIKTVTNQLAVLAREENIRLMLVTETAAPSSLEYIVDGVVTLQVKEDDRGRTRRDLRLDKLRGVRIGNRLQPFTLADGQFQVITPVELLTIQTGTGNGTWDPLANSKAKFSTGIRDLDRILSGGYNRGSVVHLDLGPDLSRDAWSVLTLPTIRNFLSQEMGVAVVPPREGSPGLLHNDLNTVLSSQVFDTYCHVFETYAGPSDSADRYDQPDSTESFSEMATTTPPDDAPTATHETDGADDGSRSTDGVTGSDQPHPIDEDFESPIEGGQLAYEPYMAYVEQVREESEDPLLHVISMDTAQEAFETRLGDFANYVALHNDLTLLITKQGTELRTRADRVADMHFRLERSGDAIILYGENPLTPLLGIGISQSESIPKITLTEMV

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias366-382Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
X15374
EMBL· GenBank· DDBJ
CAA33435.1
EMBL· GenBank· DDBJ
Genomic DNA
M58557
EMBL· GenBank· DDBJ
AAA98195.1
EMBL· GenBank· DDBJ
Genomic DNA
X55648
EMBL· GenBank· DDBJ
CAA39171.1
EMBL· GenBank· DDBJ
Genomic DNA
AF016485
EMBL· GenBank· DDBJ
AAC82808.1
EMBL· GenBank· DDBJ
Genomic DNA
AE004438
EMBL· GenBank· DDBJ
AAG20725.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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