The yeast RAD50 gene encodes a predicted 153-kD protein containing a purine nucleotide-binding domain and two large heptad-repeat regions.Alani E., Subbiah S., Kleckner N.View abstractCited forNUCLEOTIDE SEQUENCE [GENOMIC DNA]StrainRE821CategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCGenetics 122:47-57 (1989)Cited in1
Sequence analysis of the 33 kb long region between ORC5 and SUI1 from the left arm of chromosome XIV from Saccharomyces cerevisiae.Sen-Gupta M., Gueldener U., Beinhauer J.D., Fiedler T.A., Hegemann J.H.View abstractCited forNUCLEOTIDE SEQUENCE [GENOMIC DNA]StrainATCC 96604 / S288c / FY1679CategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCYeast 13:849-860 (1997)Cited in18
The nucleotide sequence of Saccharomyces cerevisiae chromosome XIV and its evolutionary implications.Philippsen P., Kleine K., Poehlmann R., Duesterhoeft A., Hamberg K., Hegemann J.H., Obermaier B., Urrestarazu L.A., Aert R.[...], Hani J.View abstractCited forNUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]StrainATCC 204508 / S288cCategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCNature 387:93-98 (1997)Cited in99+
The reference genome sequence of Saccharomyces cerevisiae: Then and now.Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R., Costanzo M.C., Dwight S.S., Hitz B.C., Karra K.[...], Cherry J.M.View abstractCited forGENOME REANNOTATIONStrainATCC 204508 / S288cCategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCG3 (Bethesda) 4:389-398 (2014)Cited in99+
Complex formation and functional versatility of Mre11 of budding yeast in recombination.Usui T., Ohta T., Oshiumi H., Tomizawa J., Ogawa H., Ogawa T.View abstractCited forIDENTIFICATION IN THE MRE11 COMPLEX, SUBCELLULAR LOCATIONCategoriesInteraction, Subcellular LocationSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCCell 95:705-716 (1998)Cited in3
Global analysis of protein expression in yeast.Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S.View abstractCited forLEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS]CategoriesExpressionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCNature 425:737-741 (2003)Cited in99+
A multidimensional chromatography technology for in-depth phosphoproteome analysis.Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.View abstractCited forPHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-469 AND THR-568, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]CategoriesPTM / Processing, SequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCMol. Cell. Proteomics 7:1389-1396 (2008)Cited in99+
Mre11 ATLD17/18 mutation retains Tel1/ATM activity but blocks DNA double- strand break repair.Limbo O., Moiani D., Kertokalio A., Wyman C., Tainer J.A., Russell P.View abstractCited forINTERACTION WITH MRE11CategoriesInteractionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCNucleic Acids Res. 40:11435-11449 (2012)Cited in5Mapped to3
Structural mechanism of ATP-dependent DNA binding and DNA end bridging by eukaryotic Rad50.Seifert F.U., Lammens K., Stoehr G., Kessler B., Hopfner K.P.View abstractCited forFUNCTION, MUTAGENESIS OF LYS-60; ARG-1201 AND SER-1205CategoriesFunction, Phenotypes & VariantsSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCEMBO J. 35:759-772 (2016)Cited in3Mapped to2
Eukaryotic Rad50 functions as a rod-shaped dimer.Park Y.B., Hohl M., Padjasek M., Jeong E., Jin K.S., Krezel A., Petrini J.H., Cho Y.View abstractCited forFUNCTION, MUTAGENESIS OF 685-SER--TYR-688CategoriesFunction, Phenotypes & VariantsSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCNat. Struct. Mol. Biol. 24:248-257 (2017)Cited in2
MRE11-RAD50-NBS1 promotes Fanconi Anemia R-loop suppression at transcription-replication conflicts.Chang E.Y., Tsai S., Aristizabal M.J., Wells J.P., Coulombe Y., Busatto F.F., Chan Y.A., Kumar A., Dan Zhu Y.[...], Stirling P.C.View abstractCited forFUNCTIONCategoriesFunctionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCNat. Commun. 10:4265-4265 (2019)Cited in6
Mre11-Rad50 oligomerization promotes DNA double-strand break repair.Kissling V.M., Reginato G., Bianco E., Kasaciunaite K., Tilma J., Cereghetti G., Schindler N., Lee S.S., Guerois R.[...], Peter M.View abstractCited forIDENTIFICATION IN THE MRE11 COMPLEX, SUBUNITCategoriesInteractionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCNat. Commun. 13:2374-2374 (2022)Cited in3
The many interfaces of Mre11.Haber J.E.AnnotationReviewsCategoriesFunctionSourceSGD: S000005194PubMedEurope PMCCell 95:583-586 (1998)Mapped to3
Homologous recombination is required for the viability of rad27 mutants.Symington L.S.View abstractAnnotationGenetic Interactions|Strains/Constructs|Mutants/Phenotypes|Primary Literature|Function/ProcessCategoriesFunction, Phenotypes & VariantsSourceSGD: S000005194PubMedEurope PMCNucleic Acids Res 26:5589-5595 (1998)Mapped to9
Identification of genes involved in repair of DNA double-strand breaks in mammalian cells.Jeggo P.A.View abstractAnnotationS000005194CategoriesFunctionSourceSGD: S000005194PubMedEurope PMCRadiat Res 150:S80-91 (1998)Mapped to7
The 3' to 5' exonuclease activity of Mre 11 facilitates repair of DNA double-strand breaks.Paull T.T., Gellert M.View abstractAnnotationProtein-protein Interactions|Non-Fungal Related Genes/Proteins|Primary Literature|Function/ProcessCategoriesFunctionSourceSGD: S000005194PubMedEurope PMCMol. Cell 1:969-979 (1998)Cited in3Mapped to1
The RAD52 recombinational repair pathway is essential in pol30 (PCNA) mutants that accumulate small single-stranded DNA fragments during DNA synthesis.Merrill B.J., Holm C.View abstractAnnotationGenetic Interactions|Strains/Constructs|Mutants/Phenotypes|Primary Literature|Function/ProcessCategoriesFunction, Phenotypes & VariantsSourceSGD: S000005194PubMedEurope PMCGenetics 148:611-624 (1998)Mapped to10
Mutations in the MRE11, RAD50, XRS2, and MRE2 genes alter chromatin configuration at meiotic DNA double-stranded break sites in premeiotic and meiotic cells.Ohta K., Nicolas A., Furuse M., Nabetani A., Ogawa H., Shibata T.View abstractAnnotationGenetic Interactions|Strains/Constructs|Mutants/Phenotypes|Protein-Nucleic Acid Interactions|Primary Literature|Function/ProcessCategoriesFunction, Phenotypes & VariantsSourceSGD: S000005194PubMedEurope PMCProc Natl Acad Sci U S A 95:646-651 (1998)Mapped to4
Alteration of telomeric sequences and senescence caused by mutations in RAD50 of Saccharomyces cerevisiae.Kironmai K.M., Muniyappa K.View abstractAnnotationStrains/Constructs|Mutants/Phenotypes|Substrates/Ligands/Cofactors|Primary Literature|Function/ProcessCategoriesFunction, Phenotypes & VariantsSourceSGD: S000005194PubMedEurope PMCGenes Cells 2:443-455 (1997)Mapped to1
Meiotic chromosomes: it takes two to tango.Roeder G.S.AnnotationPrimary LiteratureCategoriesFunctionSourceSGD: S000005194PubMedEurope PMCGenes Dev 11:2600-2621 (1997)Mapped to20
A general method for identifying recessive diploid-specific mutations in Saccharomyces cerevisiae, its application to the isolation of mutants blocked at intermediate stages of meiotic prophase and characterization of a new gene SAE2.McKee A.H.Z., Kleckner N.View abstractAnnotationMutants/Phenotypes|Techniques and Reagents|Fungal Related Genes/Proteins|Primary LiteratureCategoriesPhenotypes & VariantsSourceSGD: S000005194PubMedEurope PMCGenetics 146:797-816 (1997)Cited in1Mapped to3
The RAD52 epistasis group in mammalian double strand break repair.Petrini J.H., Bressan D.A., Yao M.S.View abstractAnnotationReviews|Non-Fungal Related Genes/ProteinsCategoriesFunctionSourceSGD: S000005194PubMedEurope PMCSemin Immunol 9:181-188 (1997)Mapped to7
A super new twist on the initiation of meiotic recombination.Haber J.E.AnnotationReviewsCategoriesFunction, SequencesSourceSGD: S000005194PubMedEurope PMCCell 89:163-166 (1997)Mapped to2
Meiotic cells monitor the status of the interhomolog recombination complex.Xu L., Weiner B.M., Kleckner N.View abstractAnnotationGenetic Interactions|Mutants/Phenotypes|Primary Literature|Function/ProcessCategoriesFunctionSourceSGD: S000005194PubMedEurope PMCGenes Dev 11:106-118 (1997)Mapped to5
Mouse RAD50 has limited epitopic homology to p53 and is expressed in the adult myocardium.Kim K.K., Daud A.I., Wong S.C., Pajak L., Tsai S.-C., Wang H., Henzel W.J., Field L.J.View abstractAnnotationCross-species Expression|Strains/Constructs|Non-Fungal Related Genes/Proteins|Primary LiteratureCategoriesSequencesSourceSGD: S000005194PubMedEurope PMCJ. Biol. Chem. 271:29255-29264 (1996)Cited in1Mapped to7