P12399 · CTL2A_MOUSE
- ProteinProtein CTLA-2-alpha
- GeneCtla2a
- StatusUniProtKB reviewed (Swiss-Prot)
- Organism
- Amino acids137 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score4/5
Function
function
Not known, expressed in activated T-cell.
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | dendrite | |
Cellular Component | extracellular region | |
Biological Process | negative regulation of inflammatory response | |
Biological Process | negative regulation of protein processing | |
Biological Process | regulation of regulatory T cell differentiation |
Protein family/group databases
Names & Taxonomy
Protein names
- Recommended nameProtein CTLA-2-alpha
- Alternative names
Gene names
Organism names
- Organism
- Strains
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus
Accessions
- Primary accessionP12399
- Secondary accessions
Proteomes
Organism-specific databases
Subcellular Location
PTM/Processing
Features
Showing features for signal, chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-27 | |||||
Sequence: MMVSICEQKLQHFSAVFLLILCLGMMS | ||||||
Chain | PRO_0000026485 | 28-137 | Protein CTLA-2-alpha | |||
Sequence: AAPPPDPSLDNEWKEWKTKFAKAYNLNEERHRRLVWEENKKKIEAHNADYEQGKTSFYMGLNQFSDLTPEEFKTNCYGNSLNRGEMAPDLPEYEDLGKNSYLTPGRAQPE |
Proteomic databases
PTM databases
Expression
Gene expression databases
Structure
Family & Domains
Features
Showing features for repeat, region.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Repeat | 39-41 | 1 | ||||
Sequence: EWK | ||||||
Region | 39-44 | 2 X 3 AA tandem repeats of E-W-K | ||||
Sequence: EWKEWK | ||||||
Repeat | 42-44 | 2 | ||||
Sequence: EWK | ||||||
Region | 114-137 | Disordered | ||||
Sequence: APDLPEYEDLGKNSYLTPGRAQPE |
Sequence similarities
To the propeptide regions of cysteine proteases.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Sequence processingThe displayed sequence is further processed into a mature form.
- Length137
- Mass (Da)15,883
- Last updated2007-07-10 v2
- ChecksumE494B682057C35C9
Computationally mapped potential isoform sequences
There is 1 potential isoform mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A286YCS9 | A0A286YCS9_MOUSE | Ctla2a | 38 |
Sequence caution
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
X15591 EMBL· GenBank· DDBJ | CAA33614.1 EMBL· GenBank· DDBJ | mRNA | Different initiation | |
AY034577 EMBL· GenBank· DDBJ | AAK58453.1 EMBL· GenBank· DDBJ | mRNA | ||
AY034580 EMBL· GenBank· DDBJ | AAK58456.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AK005471 EMBL· GenBank· DDBJ | BAB24061.2 EMBL· GenBank· DDBJ | mRNA | ||
AK167433 EMBL· GenBank· DDBJ | BAE39520.1 EMBL· GenBank· DDBJ | mRNA | ||
AK167664 EMBL· GenBank· DDBJ | BAE39714.1 EMBL· GenBank· DDBJ | mRNA | ||
BC028437 EMBL· GenBank· DDBJ | AAH28437.1 EMBL· GenBank· DDBJ | mRNA |