P12399 · CTL2A_MOUSE

  • Protein
    Protein CTLA-2-alpha
  • Gene
    Ctla2a
  • Status
    UniProtKB reviewed (Swiss-Prot)
  • Amino acids
  • Protein existence
    Evidence at transcript level
  • Annotation score
    4/5

Function

function

Not known, expressed in activated T-cell.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentdendrite
Cellular Componentextracellular region
Biological Processnegative regulation of inflammatory response
Biological Processnegative regulation of protein processing
Biological Processregulation of regulatory T cell differentiation

Protein family/group databases

Names & Taxonomy

Protein names

  • Recommended name
    Protein CTLA-2-alpha
  • Alternative names
    • Cytotoxic T-lymphocyte-associated protein 2-alpha

Gene names

    • Name
      Ctla2a

Organism names

  • Taxonomic identifier
  • Strains
    • C57BL/10-BR
    • 129/SvEvTacfBr
    • C57BL/6J
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus

Accessions

  • Primary accession
    P12399
  • Secondary accessions
    • Q91V07

Proteomes

Organism-specific databases

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for signal, chain.

TypeIDPosition(s)Description
Signal1-27
ChainPRO_000002648528-137Protein CTLA-2-alpha

Proteomic databases

PTM databases

Expression

Gene expression databases

Interaction

Protein-protein interaction databases

Miscellaneous

Structure

Family & Domains

Features

Showing features for repeat, region.

TypeIDPosition(s)Description
Repeat39-411
Region39-442 X 3 AA tandem repeats of E-W-K
Repeat42-442
Region114-137Disordered

Sequence similarities

To the propeptide regions of cysteine proteases.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    137
  • Mass (Da)
    15,883
  • Last updated
    2007-07-10 v2
  • Checksum
    E494B682057C35C9
MMVSICEQKLQHFSAVFLLILCLGMMSAAPPPDPSLDNEWKEWKTKFAKAYNLNEERHRRLVWEENKKKIEAHNADYEQGKTSFYMGLNQFSDLTPEEFKTNCYGNSLNRGEMAPDLPEYEDLGKNSYLTPGRAQPE

Computationally mapped potential isoform sequences

There is 1 potential isoform mapped to this entry

View all
EntryEntry nameGene nameLength
A0A286YCS9A0A286YCS9_MOUSECtla2a38

Sequence caution

The sequence CAA33614.1 differs from that shown. Reason: Erroneous initiation

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
X15591
EMBL· GenBank· DDBJ
CAA33614.1
EMBL· GenBank· DDBJ
mRNA Different initiation
AY034577
EMBL· GenBank· DDBJ
AAK58453.1
EMBL· GenBank· DDBJ
mRNA
AY034580
EMBL· GenBank· DDBJ
AAK58456.1
EMBL· GenBank· DDBJ
Genomic DNA
AK005471
EMBL· GenBank· DDBJ
BAB24061.2
EMBL· GenBank· DDBJ
mRNA
AK167433
EMBL· GenBank· DDBJ
BAE39520.1
EMBL· GenBank· DDBJ
mRNA
AK167664
EMBL· GenBank· DDBJ
BAE39714.1
EMBL· GenBank· DDBJ
mRNA
BC028437
EMBL· GenBank· DDBJ
AAH28437.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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