P11927 · KAR1_YEAST

Function

function

KAR1 is required for function of both intranuclear and extranuclear microtubules. KAR1 helps localize CDC31 to the spindle pole body (SPB), CDC31 then initiates SPB duplication via interaction with a downstream effector.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentendoplasmic reticulum
Cellular Componenthalf bridge of spindle pole body
Cellular Componentmicrotubule
Biological Processcell division
Biological Processkaryogamy involved in conjugation with cellular fusion
Biological Processspindle pole body duplication

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Cell division control protein KAR1

Gene names

    • Name
      KAR1
    • ORF names
      N1611
    • Ordered locus names
      YNL188W

Organism names

Accessions

  • Primary accession
    P11927
  • Secondary accessions
    • D6W0Z9
    • E9P8Y4

Proteomes

Organism-specific databases

PTM/Processing

Features

Showing features for chain, modified residue.

TypeIDPosition(s)Description
ChainPRO_00000842951-433Cell division control protein KAR1
Modified residue233Phosphothreonine

Keywords

Proteomic databases

PTM databases

Interaction

Subunit

Interacts with SPC72.

Protein-protein interaction databases

Miscellaneous

Family & Domains

Features

Showing features for compositional bias, region.

TypeIDPosition(s)Description
Compositional bias1-17Polar residues
Region1-38Disordered
Region69-101Disordered
Region207-227Disordered

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    433
  • Mass (Da)
    50,653
  • Last updated
    1996-10-01 v2
  • Checksum
    D65331B3B2B068E4
MNVTSPKDGNHSFSKKNRFNTNKPRFHKLNEQAQSINLPEDRDSIVSSNTTSIMTDDAFDYNEGIASRTKNINSDSDRSNDTIKQNNYNKRETGYNPFYNGSGINQRYTQFRKREFEPTLAENKAEEYISDEDNVKIDEDNIENELQFTPKIKEASILRSSLLGQRNVLNTRNPKSKESHIKVKPIINNKSSSQRKSSAALRKQLGKPLPLPYLNSPNSDSTPTLQRKEEVFTDEVLQKKRELIESKWHRLLFHDKKMVEKKLESLREYERKRMPPRGTDVSSSEQDNSFKISTPTKSYVSLEQKPLPNLSAMNNFNDVTDNKEKEETNNNILKFQAQRDPLQILQSEIEMHTKKLDTIIELLKDDTDSKEKRKVVTNDNAAPEQMVNKGWRKNVMMIYKKSGNIMKKYREYFLWTICILILLYCNIYVYYRF

Features

Showing features for compositional bias, sequence conflict.

TypeIDPosition(s)Description
Compositional bias1-17Polar residues
Sequence conflict95in Ref. 4; AAT92901
Sequence conflict199in Ref. 1; AAA34716

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
M15683
EMBL· GenBank· DDBJ
AAA34716.1
EMBL· GenBank· DDBJ
Genomic DNA
Z71464
EMBL· GenBank· DDBJ
CAA96082.1
EMBL· GenBank· DDBJ
Genomic DNA
AY692882
EMBL· GenBank· DDBJ
AAT92901.1
EMBL· GenBank· DDBJ
Genomic DNA
BK006947
EMBL· GenBank· DDBJ
DAA10365.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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