B lymphocyte lineage-restricted expression of mb-1, a gene with CD3-like structural properties.Sakaguchi N., Kashiwamura S., Kimoto M., Thalmann P., Melchers F.View abstractCited forNUCLEOTIDE SEQUENCE [MRNA]StrainC57BL/6 X DBA/2JCategorySequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCEMBO J. 7:3457-3464 (1988)Cited in2
Structure of the murine mb-1 gene encoding a putative sIgM-associated molecule.Kashiwamura S., Koyama T., Matsuo T., Steinmetz M., Kimoto M., Sakaguchi N.View abstractCited forNUCLEOTIDE SEQUENCE [GENOMIC DNA]StrainBALB/cJTissueLiverCategorySequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCJ. Immunol. 145:337-343 (1990)Cited in1
Molecular cloning of the Ig-alpha subunit of the human B-cell antigen receptor complex.Flaswinkel H., Reth M.Cited forNUCLEOTIDE SEQUENCECategorySequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCImmunogenetics 36:266-269 (1992)Cited in2
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).The MGC Project TeamView abstractCited forNUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]StrainC57BL/6JTissueMammary glandCategorySequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCGenome Res. 14:2121-2127 (2004)Cited in99+99+
Heterogeneously initiated transcription from the pre-B- and B-cell- specific mb-1 promoter: analysis of the requirement for upstream factor- binding sites and initiation site sequences.Travis A., Hagman J., Grosschedl R.View abstractCited forNUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-15CategorySequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCMol. Cell. Biol. 11:5756-5766 (1991)Cited in1
Identification of the genes encoding the IgM-alpha and Ig-beta components of the IgM antigen receptor complex by amino-terminal sequencing.Hombach J., Lottspeich F., Reth M.View abstractCited forPROTEIN SEQUENCE OF 29-38CategorySequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCEur. J. Immunol. 20:2795-2799 (1990)Cited in1
IgM antigen receptor complex contains phosphoprotein products of B29 and mb-1 genes.Campbell K.S., Hager E.J., Friedrich R.J., Cambier J.C.View abstractCited forPROTEIN SEQUENCE OF 29-38CategorySequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCProc. Natl. Acad. Sci. U.S.A. 88:3982-3986 (1991)Cited in1
The MB-1/B29 heterodimer couples the B cell antigen receptor to multiple src family protein tyrosine kinases.Lin J., Justement L.B.View abstractCited forINTERACTION WITH BLKCategoryInteractionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCJ. Immunol. 149:1548-1555 (1992)Cited in3Mapped to72
B-cell antigen receptor motifs have redundant signalling capabilities and bind the tyrosine kinases PTK72, Lyn and Fyn.Law D.A., Chan V.W., Datta S.K., DeFranco A.L.View abstractCited forINTERACTION WITH LYN, PHOSPHORYLATIONCategoriesPTM / Processing, InteractionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCCurr. Biol. 3:645-657 (1993)Cited in3
Dual role of the tyrosine activation motif of the Ig-alpha protein during signal transduction via the B cell antigen receptor.Flaswinkel H., Reth M.View abstractCited forPHOSPHORYLATION AT TYR-182, MUTAGENESIS OF TYR-176; TYR-182 AND TYR-193CategoriesPTM / Processing, Phenotypes & VariantsSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCEMBO J. 13:83-89 (1994)Cited in1Mapped to72
Analysis of Ig-alpha-tyrosine kinase interaction reveals two levels of binding specificity and tyrosine phosphorylated Ig-alpha stimulation of Fyn activity.Clark M.R., Johnson S.A., Cambier J.C.View abstractCited forINTERACTION WITH FYN AND LYNCategoryInteractionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCEMBO J. 13:1911-1919 (1994)Cited in3
Activation of B- and T-cells by the cytoplasmic domains of the B-cell antigen receptor proteins Ig-alpha and Ig-beta.Taddie J.A., Hurley T.R., Hardwick B.S., Sefton B.M.View abstractCited forFUNCTIONCategoryFunctionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCJ. Biol. Chem. 269:13529-13535 (1994)Cited in2
Syk protein-tyrosine kinase is regulated by tyrosine-phosphorylated Ig alpha/Ig beta immunoreceptor tyrosine activation motif binding and autophosphorylation.Rowley R.B., Burkhardt A.L., Chao H.-G., Matsueda G.R., Bolen J.B.View abstractCited forINTERACTION WITH SYKCategoryInteractionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCJ. Biol. Chem. 270:11590-11594 (1995)Cited in2Mapped to70
Reconstitution of the B cell antigen receptor signaling components in COS cells.Saouaf S.J., Kut S.A., Fargnoli J., Rowley R.B., Bolen J.B., Mahajan S.View abstractCited forINTERACTION WITH BLK, PHOSPHORYLATION AT TYR-182 AND TYR-193CategoriesPTM / Processing, InteractionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCJ. Biol. Chem. 270:27072-27078 (1995)Cited in3Mapped to73
The two membrane isoforms of human IgE assemble into functionally distinct B cell antigen receptors.Batista F.D., Anand S., Presani G., Efremov D.G., Burrone O.R.View abstractCited forSUBUNITCategoryInteractionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCJ. Exp. Med. 184:2197-2205 (1996)Cited in3
A tyrosine-based signal present in Ig alpha mediates B cell receptor constitutive internalization.Cassard S., Salamero J., Hanau D., Spehner D., Davoust J., Fridman W.H., Bonnerot C.View abstractCited forFUNCTION, MUTAGENESIS OF TYR-182 AND TYR-193CategoriesFunction, Phenotypes & VariantsSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCJ. Immunol. 160:1767-1773 (1998)Cited in1
A negative regulatory role for Ig-alpha during B cell development.Torres R.M., Hafen K.View abstractCited forFUNCTIONCategoryFunctionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCImmunity 11:527-536 (1999)Cited in1Mapped to1
A role for lipid rafts in B cell antigen receptor signaling and antigen targeting.Cheng P.C., Dykstra M.L., Mitchell R.N., Pierce S.K.View abstractCited forSUBCELLULAR LOCATIONCategorySubcellular LocationSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCJ. Exp. Med. 190:1549-1560 (1999)Cited in2Mapped to1
Ig alpha and Ig beta are required for efficient trafficking to late endosomes and to enhance antigen presentation.Siemasko K., Eisfelder B.J., Stebbins C., Kabak S., Sant A.J., Song W., Clark M.R.View abstractCited forFUNCTIONCategoryFunctionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCJ. Immunol. 162:6518-6525 (1999)Cited in2
Association of SLP-65/BLNK with the B cell antigen receptor through a non- ITAM tyrosine of Ig-alpha.Engels N., Wollscheid B., Wienands J.View abstractCited forINTERACTION WITH BLNK, PHOSPHORYLATION AT TYR-204, MUTAGENESIS OF TYR-204CategoriesPTM / Processing, Interaction, Phenotypes & VariantsSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCEur. J. Immunol. 31:2126-2134 (2001)Cited in2Mapped to72
Interference with immunoglobulin (Ig)alpha immunoreceptor tyrosine-based activation motif (ITAM) phosphorylation modulates or blocks B cell development, depending on the availability of an Igbeta cytoplasmic tail.Kraus M., Pao L.I., Reichlin A., Hu Y., Canono B., Cambier J.C., Nussenzweig M.C., Rajewsky K.View abstractCited forFUNCTION, MUTAGENESIS OF TYR-182 AND TYR-193CategoriesFunction, Phenotypes & VariantsSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCJ. Exp. Med. 194:455-469 (2001)Cited in1Mapped to3
Translocation of the B cell antigen receptor into lipid rafts reveals a novel step in signaling.Cheng P.C., Brown B.K., Song W., Pierce S.K.View abstractCited forSUBCELLULAR LOCATIONCategorySubcellular LocationSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCJ. Immunol. 166:3693-3701 (2001)Cited in2Mapped to1
Cooperative interaction of Ig(alpha) and Ig(beta) of the BCR regulates the kinetics and specificity of antigen targeting.Li C., Siemasko K., Clark M.R., Song W.View abstractCited forFUNCTIONCategoryFunctionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCInt. Immunol. 14:1179-1191 (2002)Cited in2
Receptor-facilitated antigen presentation requires the recruitment of B cell linker protein to Igalpha.Siemasko K., Skaggs B.J., Kabak S., Williamson E., Brown B.K., Song W., Clark M.R.View abstractCited forFUNCTION, INTERACTION WITH BLNK, MUTAGENESIS OF TYR-176 AND TYR-204CategoriesFunction, Interaction, Phenotypes & VariantsSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCJ. Immunol. 168:2127-2138 (2002)Cited in2Mapped to2
B cell progenitors are arrested in maturation but have intact VDJ recombination in the absence of Ig-alpha and Ig-beta.Pelanda R., Braun U., Hobeika E., Nussenzweig M.C., Reth M.View abstractCited forFUNCTION, DISRUPTION PHENOTYPECategoriesFunction, Phenotypes & VariantsSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCJ. Immunol. 169:865-872 (2002)Cited in2Mapped to2