P11612 · PPY_DROME
- ProteinSerine/threonine-protein phosphatase PP-Y
- GenePpY-55A
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids314 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score3/5
Function
Catalytic activity
- O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate
Cofactor
Note: Binds 2 manganese ions per subunit.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 60 | Mn2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 62 | Mn2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 88 | Mn2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 88 | Mn2+ 2 (UniProtKB | ChEBI) | |||
Binding site | 120 | Mn2+ 2 (UniProtKB | ChEBI) | |||
Active site | 121 | Proton donor | |||
Binding site | 169 | Mn2+ 2 (UniProtKB | ChEBI) | |||
Binding site | 244 | Mn2+ 2 (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Cellular Component | nucleus | |
Molecular Function | metal ion binding | |
Molecular Function | myosin phosphatase activity | |
Molecular Function | protein serine/threonine phosphatase activity |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameSerine/threonine-protein phosphatase PP-Y
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Diptera > Brachycera > Muscomorpha > Ephydroidea > Drosophilidae > Drosophila > Sophophora
Accessions
- Primary accessionP11612
- Secondary accessions
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000058889 | 1-314 | Serine/threonine-protein phosphatase PP-Y | ||
Proteomic databases
Expression
Gene expression databases
Structure
Sequence
- Sequence statusComplete
- Length314
- Mass (Da)35,980
- Last updated2005-08-30 v2
- Checksum6078CB66571261F0
Computationally mapped potential isoform sequences
There is 1 potential isoform mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A0B4LFR7 | A0A0B4LFR7_DROME | PpY-55A | 314 |
Features
Showing features for sequence conflict.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Sequence conflict | 66 | in Ref. 6; AAB22467 | |||
Sequence conflict | 123 | in Ref. 1 and 2 | |||
Sequence conflict | 147 | in Ref. 1 and 2 | |||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
Y07510 EMBL· GenBank· DDBJ | CAA68808.1 EMBL· GenBank· DDBJ | mRNA | ||
AE013599 EMBL· GenBank· DDBJ | AAF57771.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AY075165 EMBL· GenBank· DDBJ | AAL68035.1 EMBL· GenBank· DDBJ | mRNA | ||
S40001 EMBL· GenBank· DDBJ | AAB22467.1 EMBL· GenBank· DDBJ | Genomic DNA |