P11228 · SOMA_ANAPL

Function

function

Growth hormone plays an important role in growth control.

Features

Showing features for binding site.

121620406080100120140160180200
TypeIDPosition(s)Description
Binding site46Zn2+ (UniProtKB | ChEBI)
Binding site198Zn2+ (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentextracellular space
Molecular Functioncysteine-type endopeptidase activity involved in apoptotic process
Molecular Functiongrowth factor activity
Molecular Functiongrowth hormone receptor binding
Molecular Functionhormone activity
Molecular Functionmetal ion binding
Biological Processanimal organ development
Biological Processgrowth hormone receptor signaling pathway
Biological Processnegative regulation of apoptotic process
Biological Processnegative regulation of gene expression
Biological Processoviduct epithelium development
Biological Processpositive regulation of gene expression
Biological Processpositive regulation of growth
Biological Processpositive regulation of receptor signaling pathway via JAK-STAT
Biological Processpositive regulation of tyrosine phosphorylation of STAT protein
Biological Processresponse to nutrient levels

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Somatotropin
  • Alternative names
    • Growth hormone

Gene names

    • Name
      GH

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Archelosauria > Archosauria > Dinosauria > Saurischia > Theropoda > Coelurosauria > Aves > Neognathae > Galloanserae > Anseriformes > Anatidae > Anatinae > Anas

Accessions

  • Primary accession
    P11228

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for signal, chain, disulfide bond.

Type
IDPosition(s)Description
Signal1-25
ChainPRO_000003300326-216Somatotropin
Disulfide bond78↔189
Disulfide bond206↔214

Keywords

Structure

Family & Domains

Sequence similarities

Belongs to the somatotropin/prolactin family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    216
  • Mass (Da)
    24,896
  • Last updated
    1989-07-01 v1
  • Checksum
    3A10C0AC18BB30F0
MAPGSWFSPLFITVITLGLQWPQEAATFPAMPLSNLFANAVLRAQHLHLLAAETYKEFERSYIPEDQRHTNKNSQAFCYSETIPAPTGKDDAQQKSDMELLRFSLVLIQSWLTPVQYLSKVFTNNLVFGTSDRVFEKLKDLEEGIQALMRELEDRSPRGPQLLKPTYDKFDIHLRNEDALLKNYGLLSCFKKDLHKVETYLKVMKCRRFGESNCTI

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
X07079
EMBL· GenBank· DDBJ
CAA30113.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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