Isolation and characterization of expressible cDNA clones encoding the M1 and M2 subunits of mouse ribonucleotide reductase.Thelander L., Berg P.View abstractCited forNUCLEOTIDE SEQUENCE [MRNA]CategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCMol. Cell. Biol. 6:3433-3442 (1986)Cited in1Mapped to8
Molecular cloning and expression of the functional gene encoding the M2 subunit of mouse ribonucleotide reductase: a new dominant marker gene.Thelander M., Thelander L.View abstractCited forNUCLEOTIDE SEQUENCE [GENOMIC DNA]CategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCEMBO J. 8:2475-2479 (1989)Cited in1Mapped to3
The transcriptional landscape of the mammalian genome.Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B.[...], Hayashizaki Y.View abstractCited forNUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]StrainC57BL/6J, DBA/2J, NODTissueEye, Kidney, Liver, ThymusCategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCScience 309:1559-1563 (2005)Cited in99+16Mapped to99+
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).The MGC Project TeamView abstractCited forNUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]StrainC57BL/6JTissueBrainCategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCGenome Res. 14:2121-2127 (2004)Cited in99+99+
Large-scale phosphorylation analysis of mouse liver.Villen J., Beausoleil S.A., Gerber S.A., Gygi S.P.View abstractCited forPHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-20, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]TissueLiverCategoriesPTM / Processing, SequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCProc. Natl. Acad. Sci. U.S.A. 104:1488-1493 (2007)Cited in99+99+Mapped to1
Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry.Sweet S.M., Bailey C.M., Cunningham D.L., Heath J.K., Cooper H.J.View abstractCited forPHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-20, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]TissueEmbryonic fibroblastCategoriesPTM / Processing, SequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCMol. Cell. Proteomics 8:904-912 (2009)Cited in99+99+
A tissue-specific atlas of mouse protein phosphorylation and expression.Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R., Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.View abstractCited forPHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-20 AND THR-33, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]TissueBrown adipose tissue, Kidney, Lung, Spleen, TestisCategoriesPTM / Processing, SequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCCell 143:1174-1189 (2010)Cited in99+99+Mapped to6
The three-dimensional structure of mammalian ribonucleotide reductase protein R2 reveals a more-accessible iron-radical site than Escherichia coli R2.Kauppi B., Nielsen B.B., Ramaswamy S., Larsen I.K., Thelander M., Thelander L., Eklund H.View abstractCited forX-RAY CRYSTALLOGRAPHY (2.3 ANGSTROMS) OF 65-352CategoriesStructureSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCJ. Mol. Biol. 262:706-720 (1996)Cited in1Mapped to3
Cobalt substitution of mouse R2 ribonucleotide reductase as a model for the reactive diferrous state. Spectroscopic and structural evidence for a ferromagnetically coupled dinuclear cobalt cluster.Strand K.R., Karlsen S., Andersson K.K.View abstractCited forX-RAY CRYSTALLOGRAPHY (2.2 ANGSTROMS) OF 65-352CategoriesStructureSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCJ. Biol. Chem. 277:34229-34238 (2002)Cited in1Mapped to1
NMR structure of an inhibitory R2 C-terminal peptide bound to mouse ribonucleotide reductase R1 subunit.Fisher A.L., Laub P.B., Cooperman B.S.View abstractCited forSTRUCTURE BY NMR OF 384-390CategoriesStructureSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCNat. Struct. Biol. 2:951-955 (1995)Cited in1
Mapping of the ribonucleotide reductase genes (Rrm1, Rrm2) in the rat.Klinga-Levan K., Helou K., Issa R., Szpirer C., Szpirer J., Levan G.CategoriesFunctionSourceMGI: 98181PubMedEurope PMCMamm Genome 8:47-49 (1997)Mapped to9
Genetic regulation of cholesterol homeostasis: chromosomal organization of candidate genes.Welch C.L., Xia Y.R., Shechter I., Farese R., Mehrabian M., Mehdizadeh S., Warden C.H., Lusis A.J.View abstractCategoriesSequencesSourceMGI: 98181PubMedEurope PMCJ Lipid Res 37:1406-1421 (1996)Mapped to99+
Cloning of a third mammalian Na+-Ca2+ exchanger, NCX3.Nicoll D.A., Quednau B.D., Qui Z., Xia Y.-R., Lusis A.J., Philipson K.D.View abstractCategoriesSequencesSourceMGI: 98181PubMedEurope PMCJ. Biol. Chem. 271:24914-24921 (1996)Cited in3Mapped to99+
A novel family of Cys-Cys, His-Cys zinc finger transcription factors expressed in developing nervous system and pituitary gland.Jiang Y., Yu V.C., Buchholz F., O'Connell S., Rhodes S.J., Candeloro C., Xia Y.-R., Lusis A.J., Rosenfeld M.G.View abstractCategoriesSequencesSourceMGI: 98181PubMedEurope PMCJ. Biol. Chem. 271:10723-10730 (1996)Cited in1Mapped to56
A link between ferritin gene expression and ribonucleotide reductase R2 protein, as demonstrated by retroviral vector mediated stable expression of R2 cDNA.Fan H., Villegas C., Wright J.A.View abstractCategoriesSequencesSourceMGI: 98181PubMedEurope PMCFEBS Lett 382:145-148 (1996)Mapped to9
Linkage mapping of 40 randomly isolated liver cDNA clones in the mouse.Warden C.H., Mehrabian M., He K.Y., Yoon M.Y., Diep A., Xia Y.R., Wen P.Z., Svenson K.L., Sparkes R.S., Lusis A.J.View abstractCategoriesSequencesSourceMGI: 98181PubMedEurope PMCGenomics 18:295-307 (1993)Mapped to99+
1H NMR studies of mouse ribonucleotide reductase: the R2 protein carboxyl- terminal tail, essential for subunit interaction, is highly flexible but becomes rigid in the presence of protein R1.Lycksell P.O., Ingemarson R., Davis R., Graslund A., Thelander L.View abstractCategoriesStructureSourceMGI: 98181PubMedEurope PMCBiochemistry 33:2838-2842 (1994)Mapped to9
Refinement of the DNA marker maps of mouse chromosome 12.Khan F., Clarke V., D'Eustachio P.View abstractCategoriesSequencesSourceMGI: 98181PubMedEurope PMCGenomics 21:128-137 (1994)Mapped to47
Genetic determinants of micronucleus formation in vivo.Adams D.J., Barlas B., McIntyre R.E., Salguero I., van der Weyden L., Barros A., Vicente J.R., Karimpour N., Haider A.[...], White J.K.View abstractSourceMGI: 98181PubMedEurope PMCNature 627:130-136 (2024)Mapped to99+
Identification of RRM2 as a key ferroptosis-related gene in sepsis.He S., He Y., Deng L., Guo Y., Wang X., Wang Q., Luo L., Liu Q.View abstractAnnotationIdentification of RRM2 as a key ferroptosis-related gene in sepsis.SourceGeneRif: 20135PubMedEurope PMCInflamm Res 73:459-473 (2024)Mapped to2
Targeting of RRM2 suppresses DNA damage response and activates apoptosis in atypical teratoid rhabdoid tumor.Giang L.H., Wu K.S., Lee W.C., Chu S.S., Do A.D., Changou C.A., Tran H.M., Hsieh T.H., Chen H.H.[...], Chang C.C.View abstractAnnotationTargeting of RRM2 suppresses DNA damage response and activates apoptosis in atypical teratoid rhabdoid tumor.SourceGeneRif: 20135PubMedEurope PMCJ Exp Clin Cancer Res 42:346-346 (2023)Mapped to2
Inhibition of RRM2 radiosensitizes glioblastoma and uncovers synthetic lethality in combination with targeting CHK1.Corrales-Guerrero S., Cui T., Castro-Aceituno V., Yang L., Nair S., Feng H., Venere M., Yoon S., DeWees T.[...], Williams T.M.View abstractAnnotationInhibition of RRM2 radiosensitizes glioblastoma and uncovers synthetic lethality in combination with targeting CHK1.SourceGeneRif: 20135PubMedEurope PMCCancer Lett 570:216308-216308 (2023)Mapped to4
Yap is essential for uterine decidualization through Rrm2/GSH/ROS pathway in response to Bmp2.Yu H.F., Yang Z.Q., Xu M.Y., Huang J.C., Yue Z.P., Guo B.View abstractCategoriesFunctionSourceMGI: 98181PubMedEurope PMCInt J Biol Sci 18:2261-2276 (2022)Mapped to13
RRM2 Alleviates Doxorubicin-Induced Cardiotoxicity through the AKT/mTOR Signaling Pathway.Jiao Y., Li Y., Zhang J., Zhang S., Zha Y., Wang J.View abstractAnnotationRRM2 Alleviates Doxorubicin-Induced Cardiotoxicity through the AKT/mTOR Signaling Pathway.CategoriesFunction, ExpressionSourceGeneRif: 20135PubMedEurope PMCBiomolecules 12:299-299 (2022)Mapped to2
Molecular Profiling Reveals Involvement of ESCO2 in Intermediate Progenitor Cell Maintenance in the Developing Mouse Cortex.Ulmke P.A., Sakib M.S., Ditte P., Sokpor G., Kerimoglu C., Pham L., Xie Y., Mao X., Rosenbusch J.[...], Tuoc T.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 98181PubMedEurope PMCStem Cell Reports 16:968-984 (2021)Mapped to99+