P0DXF8 · FAPF_PSEFL

  • Protein
    Probable fibril transporter FapF
  • Gene
    fapF
  • Status
    UniProtKB reviewed (Swiss-Prot)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

function

Probably transports fibril components across the outer membrane (Probable) (PubMed:23504942).
Upon overexpression of the endogenous six-gene locus (fapA-fapF) in situ cells form large clumps during liquid growth, make large amounts of biofilm and produce amyloid fibrils (PubMed:23504942, PubMed:26500638).
Expression of the 6 gene operon in E.coli strain BL21(DE3) induces flocculation and biofilm formation with copious extracellular fibrils (PubMed:20572935).

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Probable fibril transporter FapF

Gene names

    • Name
      fapF
    • ORF names
      HZ99_04105
      , PSUK4_00060

Organism names

  • Taxonomic identifier
  • Strain
    • UK4
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Pseudomonadales > Pseudomonadaceae > Pseudomonas

Accessions

  • Primary accession
    P0DXF8

Subcellular Location

Cell outer membrane

Keywords

Phenotypes & Variants

Disruption phenotype

Deletion of just fapF in an overexpressing strain yields cells without amyloid fibrils (PubMed:26500638).
Deletion of the entire fapA-fapF six-gene locus shows no visible growth phenotype (PubMed:23504942, PubMed:26500638).

PTM/Processing

Features

Showing features for signal, chain.

Type
IDPosition(s)Description
Signal1-24
ChainPRO_000046151825-430Probable fibril transporter FapF

Family & Domains

Features

Showing features for coiled coil.

TypeIDPosition(s)Description
Coiled coil30-64

Sequence similarities

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    430
  • Mass (Da)
    46,467
  • Last updated
    2024-11-27 v1
  • Checksum
    E364465EB59EA9D0
MHRSLSLRAVVCLSTLLPASLLYAAPDVDIETLKQELLELKQRYEAQQKALAVLEQRVRQVEDQPATPAPKRLAKSPADFKQSGSTVAASSGTGGATGGSSYGQSLKDDSEPAQSVSNLYNEASGFFGNGKFSFETGITYARYDARQLTLNGFLALDSIFLGNINLDRIKADNWTLDLTGRYNLDNRWQFDVNVPVVYRESTYQSGGASGGDPQATSEESVSRDPTIGDVNFGIAYKFLDESATMPDAVVSVRVKAPTGKEPFGIKLVRSTANDNLYVPESLPTGNGVWSITPGLSLVKTFDPAVLFGSVSYTHNLEDSFDDISSDVNQKVGGKVRLGDSFQFGVGVAFALNERMSMSFSVSDLIQRKSKLKPDGGGWQSIVSSDANAGYFNVGMTIAASENLTIVPNLAIGMTDDAPDFTFSLKFPYYF

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
ACOQ01000001
EMBL· GenBank· DDBJ
EEP64554.1
EMBL· GenBank· DDBJ
Genomic DNA
CP008896
EMBL· GenBank· DDBJ
AIG01394.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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